Search Results - "Liebe, Thomas"
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Association of the delayed changes in glutamate levels and functional connectivity with the immediate network effects of S-ketamine
Published in Translational psychiatry (16-02-2023)“…Ketamine shows rapid antidepressant effects peaking 24 h after administration. The antidepressant effects may occur through changes in glutamatergic metabolite…”
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CHIASM, the human brain albinism and achiasma MRI dataset
Published in Scientific data (26-11-2021)“…We describe a collection of T1-, diffusion- and functional T2*-weighted magnetic resonance imaging data from human individuals with albinism and achiasma. This…”
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Glutamate in Salience Network Predicts BOLD Response in Default Mode Network During Salience Processing
Published in Frontiers in behavioral neuroscience (02-10-2019)“…Brain investigations identified salience network (SN) comprising the dorsal Anterior Cingulate Cortex (dACC) and the Anterior Insula (AI). Magnetic resonance…”
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Ketamine influences the locus coeruleus norepinephrine network, with a dependency on norepinephrine transporter genotype – a placebo controlled fMRI study
Published in NeuroImage clinical (01-01-2018)“…Ketamine is receiving increasing attention as a rapid-onset antidepressant in patients suffering from major depressive disorder (MDD) with treatment resistance…”
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In vivo tractography of human locus coeruleus—relation to 7T resting state fMRI, psychological measures and single subject validity
Published in Molecular psychiatry (01-12-2022)“…The locus coeruleus (LC) in the brainstem as the main regulator of brain noradrenaline gains increasing attention because of its involvement in neurologic and…”
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In vivo anatomical mapping of human locus coeruleus functional connectivity at 3 T MRI
Published in Human brain mapping (01-06-2020)“…The locus coeruleus (LC) is involved in numerous crucial brain functions and several disorders like depression and Alzheimer's disease. Recently, the LC…”
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Investigation of the functional pathogenesis of mild cognitive impairment by localisation‐based locus coeruleus resting‐state fMRI
Published in Human brain mapping (15-12-2022)“…Dementia as one of the most prevalent diseases urges for a better understanding of the central mechanisms responsible for clinical symptoms, and necessitates…”
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Subanesthetic Ketamine Suppresses Locus Coeruleus-Mediated Alertness Effects: A 7T fMRI Study
Published in The international journal of neuropsychopharmacology (01-06-2024)“…Background: The NMDA antagonist S-ketamine is gaining increasing use as a rapid-acting antidepressant, although its exact mechanisms of action are still…”
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Emotion processing and regulation in major depressive disorder: A 7T resting‐state fMRI study
Published in Human brain mapping (15-02-2021)“…Dysfunctions in bottom‐up emotion processing (EP), as well as top‐down emotion regulation (ER) are prominent features in pathophysiology of major depressive…”
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Subanesthetic Ketamine Suppresses Locus Coeruleus-Mediated Alertness Effects: A 7T fMRI Study
Published in The international journal of neuropsychopharmacology (01-06-2024)“…The NMDA antagonist S-ketamine is gaining increasing use as a rapid-acting antidepressant, although its exact mechanisms of action are still unknown. In this…”
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Ketamine-induced changes in plasma brain-derived neurotrophic factor (BDNF) levels are associated with the resting-state functional connectivity of the prefrontal cortex
Published in The world journal of biological psychiatry (20-10-2020)“…Synaptic plasticity and brain-derived neurotrophic factor (BDNF) signalling are proposed to play key roles in antidepressant drug action. Ketamine, an…”
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Factors Influencing the Cardiovascular Response to Subanesthetic Ketamine: A Randomized, Placebo-Controlled Trial
Published in The international journal of neuropsychopharmacology (01-11-2017)“…Abstract Background The increasing use of ketamine as a potential rapid-onset antidepressant necessitates a better understanding of its effects on blood…”
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Chiasmal malformations dataset: a unique neuroimaging testbed
Published in Journal of vision (Charlottesville, Va.) (27-09-2021)Get full text
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Neuronal glutamatergic changes and peripheral markers of cytoskeleton dynamics change synchronically 24 h after sub-anaesthetic dose of ketamine in healthy subjects
Published in Behavioural brain research (01-02-2019)“…•PgACC glutamatergic and peripheral Acet-Tub/TRF changes are neg. correlated 24h after ketamine infusion in healthy subjects.•Gender has influence on basal…”
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Delayed increase of thrombocyte levels after a single sub-anesthetic dose of ketamine – A randomized trial
Published in European neuropsychopharmacology (01-06-2018)“…Recently, ketamine has been investigated as a potential antidepressant option for treatment resistant depression. Unlike traditional drugs, it yields immediate…”
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Magnetic measurements on the Norwegian continental margin between 68° and 70° N
Published in Deutsche Hydrographische Zeitschrift (01-05-1988)Get full text
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