Search Results - "Lieb, W."

The combined effects of alcohol consumption and body mass index on hepatic steatosis in a general population sample of European men and women by Lau, K., Baumeister, S. E., Lieb, W., Meffert, P. J., Lerch, M. M., Mayerle, J., Völzke, H.

“…Summary Background Research on the association between alcohol consumption and hepatic steatosis revealed conflictive results. Aim To investigate the…”
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Smoking Modifies the Genetic Risk for Early-Onset Periodontitis by Freitag-Wolf, S., Munz, M., Wiehe, R., Junge, O., Graetz, C., Jockel-Schneider, Y., Staufenbiel, I., Bruckmann, C., Lieb, W., Franke, A., Loos, B.G., Jepsen, S., Dommisch, H., Schaefer, A.S.

“…Periodontitis has low-prevalence, highly severe disease manifestations with an early onset and rapid progression. The diagnosis is based on severe destruction…”
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Host traits, lifestyle and environment are associated with human skin bacteria by Moitinho‐Silva, L., Boraczynski, N., Emmert, H., Baurecht, H., Szymczak, S., Schulz, H., Haller, D., Linseisen, J., Gieger, C., Peters, A., Tittmann, L., Lieb, W., Bang, C., Franke, A., Rodriguez, E., Weidinger, S.

“…Summary Background The human skin offers diverse ecosystems for microbial symbionts. However, the factors shaping skin–microbiome interactions are still…”
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Low copy numbers of complement C4 and homozygous deficiency of C4A may predispose to severe disease and earlier disease onset in patients with systemic lupus erythematosus by Jüptner, M, Flachsbart, F, Caliebe, A, Lieb, W, Schreiber, S, Zeuner, R, Franke, A, Schröder, J O

“…Objectives Low copy numbers and deletion of complement C4 genes are potent risk factors for systemic lupus erythematosus (SLE). However, it is not known…”
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Body weight gain and risk of colorectal cancer: a systematic review and meta‐analysis of observational studies by Schlesinger, S, Lieb, W, Koch, M, Fedirko, V, Dahm, C. C, Pischon, T, Nöthlings, U, Boeing, H, Aleksandrova, K

“…While the relationship between body mass index as an indicator of excess body weight and the risk of colorectal cancer (CRC) is well established, the…”
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Molecular and cellular mechanisms of general anaesthesia by Franks, N. P, Lieb, W. R

“…General anaesthetics are much more selective than is usually appreciated and may act by binding to only a small number of targets in the central nervous…”
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Small dense LDL cholesterol in human subjects with different chronic inflammatory diseases by Schulte, D.M., Paulsen, K., Türk, K., Brandt, B., Freitag-Wolf, S., Hagen, I., Zeuner, R., Schröder, J.O., Lieb, W., Franke, A., Nikolaus, S., Mrowietz, U., Gerdes, S., Schreiber, S., Laudes, M.

“…Chronic inflammatory diseases (CID) are associated with a profound increase in cardiovascular (CV) risk resulting in reduced life expectancy. However,…”
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The PF4/PPBP/CXCL5 Gene Cluster Is Associated with Periodontitis by Shusterman, A., Munz, M., Richter, G., Jepsen, S., Lieb, W., Krone, B., Hoffman, P., Laudes, M., Wellmann, J., Berger, K., Kocher, T., Offenbacher, S., Divaris, K., Franke, A., Schreiber, S., Dommisch, H., Weiss, E., Schaefer, A.S., Houri-Haddad, Y., Iraqi, F.A.

“…Periodontitis is a common dysbiotic inflammatory disease with an estimated heritability of 50%. Due to the limited sample size of available periodontitis…”
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Long-term health sequelae and quality of life at least 6 months after infection with SARS-CoV-2: design and rationale of the COVIDOM-study as part of the NAPKON population-based cohort platform (POP) by Horn, A., Krist, L., Lieb, W., Montellano, F. A., Kohls, M., Haas, K., Gelbrich, G., Bolay-Gehrig, S. J., Morbach, C., Reese, J. P., Störk, S., Fricke, J., Zoller, T., Schmidt, S., Triller, P., Kretzler, L., Rönnefarth, M., Von Kalle, C., Willich, S. N., Kurth, F., Steinbeis, F., Witzenrath, M., Bahmer, T., Hermes, A., Krawczak, M., Reinke, L., Maetzler, C., Franzenburg, J., Enderle, J., Flinspach, A., Vehreschild, J., Schons, M., Illig, T., Anton, G., Ungethüm, K., Finkenberg, B. C., Gehrig, M. T., Savaskan, N., Heuschmann, P. U., Keil, T., Schreiber, S.

“…Purpose Over the course of COVID-19 pandemic, evidence has accumulated that SARS-CoV-2 infections may affect multiple organs and have serious clinical…”
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The serotonin receptor 3E variant is a risk factor for female IBS-D by Fritz, Nikola, Berens, Sabrina, Dong, Yuanjun, Martínez, Cristina, Schmitteckert, Stefanie, Houghton, Lesley A., Goebel-Stengel, Miriam, Wahl, Verena, Kabisch, Maria, Götze, Dorothea, D’Amato, Mauro, Zheng, Tenghao, Röth, Ralph, Mönnikes, Hubert, Tesarz, Jonas, Engel, Felicitas, Gauss, Annika, Raithel, Martin, Andresen, Viola, Keller, Jutta, Frieling, Thomas, Pehl, Christian, Stein-Thöringer, Christoph, Clarke, Gerard, Kennedy, Paul J., Cryan, John F., Dinan, Timothy G., Quigley, Eamonn M. M., Spiller, Robin, Beltrán, Caroll, Madrid, Ana María, Torres, Verónica, Mayer, Emeran A., Sayuk, Gregory, Gazouli, Maria, Karamanolis, George, Bustamante, Mariona, Estivil, Xavier, Rabionet, Raquel, Hoffmann, Per, Nöthen, Markus M., Heilmann-Heimbach, Stefanie, Schmidt, Börge, Franke, André, Lieb, Wolfgang, Herzog, Wolfgang, Boeckxstaens, Guy, Wouters, Mira M., Simrén, Magnus, Rappold, Gudrun A., Vicario, Maria, Santos, Javier, Schaefert, Rainer, Lorenzo-Bermejo, Justo, Niesler, Beate

“…Irritable bowel syndrome (IBS) is a gut-brain disorder of multifactorial origin. Evidence of disturbed serotonergic function in IBS accumulated for the 5-HT 3…”
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How does xenon produce anaesthesia? by Franks, N. P, Dickinson, R, de Sousa, S. L. M, Hall, A. C, Lieb, W. R

“…Since the discovery that the gas xenon can produce general anaesthesia without causing undesirable side effects, we have remained surprisingly ignorant of the…”
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Integration of Murine and Human Studies for Mapping Periodontitis Susceptibility by Nashef, A., Qabaja, R., Salaymeh, Y., Botzman, M., Munz, M., Dommisch, H., Krone, B., Hoffmann, P., Wellmann, J., Laudes, M., Berger, K., Kocher, T., Loos, B., van der Velde, N., Uitterlinden, A.G., de Groot, L.C.P.G.M., Franke, A., Offenbacher, S., Lieb, W., Divaris, K., Mott, R., Gat-Viks, I., Wiess, E., Schaefer, A., Iraqi, F.A., Haddad, Y.H.

“…Periodontitis is one of the most common inflammatory human diseases with a strong genetic component. Due to the limited sample size of available periodontitis…”
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Persisting chemosensory dysfunction in COVID-19 - a cross-sectional population-based survey by Winkelmann, S, Korth, A, Voss, B, Nasr, M A, Behrend, N, Pudszuhn, A, Hofmann, V M, Schendzielorz, P, Maetzler, C, Hermes, A, Borzikowsky, C, Bahmer, T, Lieb, W, Schreiber, S, Stork, S, Montellano, F A, Witzenrath, M, Keil, T, Krawczak, M, Laudien, M, On Behalf Of The Napkon Study Group, Napkon Study Group

“…Chemosensory dysfunction (CD) has been reported as a common symptom of SARS-CoV-2 infection, but it is not well understood whether and for how long changes of…”
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Genome-wide association study identifies a new locus for coronary artery disease on chromosome 10p11.23 by ERDMANN, Jeanette, WILLENBORG, Christina, AHERRAHROU, Zouhair, KLOPP, Norman, LOLEY, Christina, STARK, Klaus, HENGSTENBERG, Christian, BRUSE, Petra, FREYER, Jennifer, WAGNER, Arnika K, MEDACK, Anja, LIEB, Wolfgang, NAHRSTAEDT, Janja, GROSSHENNIG, Anika, SAGER, Hendrik B, REINHARDT, Adrian, SCHÄFER, Arne, SCHREIBER, Stefan, EDDINE EL MOKHTARI, Nour, RAAZ-SCHRAUDER, Dorette, ILLIG, Thomas, GARLICHS, Christoph D, EKICI, Arif B, PREUSS, Michael, REIS, André, SCHREZENMEIR, Jürgen, RUBIN, Diana, ZIEGLER, Andreas, WICHMANN, H.-E, DOERING, Angela, MEISINGER, Christa, MEITINGER, Thomas, PETERS, Annette, SCHUNKERT, Heribert, KÖNIG, Inke R, BAUMERT, Jens, LINSEL-NITSCHKE, Patrick, GIEGER, Christian, TENNSTEDT, Stephanie, BELCREDI, Petra

“…Recent genome-wide association (GWA) studies identified 10 chromosomal loci for coronary artery disease (CAD) or myocardial infarction (MI). However, these…”
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Serum metabolomic profiling highlights pathways associated with liver fat content in a general population sample by Koch, M, Freitag-Wolf, S, Schlesinger, S, Borggrefe, J, Hov, J R, Jensen, M K, Pick, J, Markus, M R P, Höpfner, T, Jacobs, G, Siegert, S, Artati, A, Kastenmüller, G, Römisch-Margl, W, Adamski, J, Illig, T, Nothnagel, M, Karlsen, T H, Schreiber, S, Franke, A, Krawczak, M, Nöthlings, U, Lieb, W

“…Background/Objectives: Fatty liver disease (FLD) is an important intermediate trait along the cardiometabolic disease spectrum and strongly associates with…”
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Two good embryos are too good: can a simplified embryo scoring system yield fewer twins? by Chatzicharalampous, C, Lieb, W, Jenkins, J.A, Stelling, J.R, Bray, M.A

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Filtering bleb function after clear cornea phacoemulsification: a prospective study by Klink, J, Schmitz, B, Lieb, W E, Klink, T, Grein, H-J, Sold-Darseff, J, Heinold, A, Grehn, F

“…Aim: To evaluate the influence of clear cornea phacoemulsification on filtering bleb morphology, function, and intraocular pressure (IOP) in glaucomatous eyes…”
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Strategies for Personalized Medicine-Based Research and Implementation in the Clinical Workflow by Lieb, W, Völzke, H, Pulley, J M, Roden, D M, Kroemer, H K

“…The decoding of the human genome, paralleled by the development of high‐throughput technologies to obtain large‐scale molecular data (e.g., information on…”
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Differential sensitivities of mammalian neuronal and muscle nicotinic acetylcholine receptors to general anesthetics by VIOLET, J. M, DOWNIE, D. L, NAKISA, R. C, LIEB, W. R, FRANKS, N. P

“…Nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of fast neurotransmitter-gated receptor channels that includes the gamma-aminobutyric…”
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Two models of inescapable stress increase tph2 mRNA expression in the anxiety-related dorsomedial part of the dorsal raphe nucleus by Donner, Nina C., Kubala, Kenneth H., Hassell Jr, James E., Lieb, Margaret W., Nguyen, Kadi T., Heinze, Jared D., Drugan, Robert C., Maier, Steven F., Lowry, Christopher A.

“…Expression of TPH2, the rate-limiting enzyme for brain serotonin synthesis, is elevated in the dorsal raphe nucleus (DR) of depressed suicide victims. One…”
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