Search Results - "Lie, B.A"

OC-18 The link between the hemostatic system and cancer: A genotypephenotype study in breast cancer patients by Tinholt, M, Viken, M.K, Børresen-Dale, A.L, Kristensen, V, Kåresen, R, Schlichting, E, Øystein, G, Lie, B.A, Dahm, A.E, Skretting, G, Sandset, P.M, Iversen, N

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22 ELECTROSTATIC MODIFICATIONS OF THE HLA-DR P9 PEPTIDE-BINDING POCKET AND SUSCEPTIBILITY TO PRIMARY SCLEROSING CHOLANGITIS by Hov, J.R, Kosmoliaptsis, V, Traherne, J.A, Olsson, M, Boberg, K.M, Bergquist, A, Schrumpf, E, Bradley, J.A, Taylor, C.J, Lie, B.A, Trowsdale, J, Karlsen, T.H

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Genetic pleiotropy between multiple sclerosis and schizophrenia but not bipolar disorder: differential involvement of immune-related gene loci by Andreassen, O A, Harbo, H F, Wang, Y, Thompson, W K, Schork, A J, Mattingsdal, M, Zuber, V, Bettella, F, Ripke, S, Kelsoe, J R, Kendler, K S, O'Donovan, M C, Sklar, P, McEvoy, L K, Desikan, R S, Lie, B A, Djurovic, S, Dale, A M

“…Converging evidence implicates immune abnormalities in schizophrenia (SCZ), and recent genome-wide association studies (GWAS) have identified immune-related…”
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A coding polymorphism in NALP1 confers risk for autoimmune Addison's disease and type 1 diabetes by Magitta, N F, Bøe Wolff, A S, Johansson, S, Skinningsrud, B, Lie, B A, Myhr, K-M, Undlien, D E, Joner, G, Njølstad, P R, Kvien, T K, Førre, Ø, Knappskog, P M, Husebye, E S

“…Variants in the gene encoding NACHT leucine-rich-repeat protein 1 (NALP1), an important molecule in innate immunity, have recently been shown to confer risk…”
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Coeliac disease-associated polymorphisms influence thymic gene expression by Amundsen, S S, Viken, M K, Sollid, L M, Lie, B A

“…Significant associations between coeliac disease (CD) and single nucleotide polymorphisms (SNPs) distributed over 40 genetic regions have been established. The…”
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Multiple sclerosis-associated single-nucleotide polymorphisms in CLEC16A correlate with reduced SOCS1 and DEXI expression in the thymus by Leikfoss, I S, Mero, I-L, Dahle, M K, Lie, B A, Harbo, H F, Spurkland, A, Berge, T

“…Genome-wide association studies have revealed that the 16p13 chromosomal region, including CLEC16A , DEXI, CIITA and SOCS1 , is associated with susceptibility…”
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The association of PTPN22 rs2476601 with juvenile idiopathic arthritis is specific to females by Chiaroni-Clarke, R C, Li, Y R, Munro, J E, Chavez, R A, Scurrah, K J, Pezic, A, Akikusa, J D, Allen, R C, Piper, S E, Becker, M L, Thompson, S D, Lie, B A, Flato, B, Forre, O, Punaro, M, Wise, C, Saffery, R, Finkel, T H, Hakonarson, H, Ponsonby, A-L, Ellis, J A

“…A preponderance of females develop autoimmune disease, including juvenile idiopathic arthritis (JIA), yet the reason for this bias remains elusive. Evidence…”
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Reproducible association with type 1 diabetes in the extended class I region of the major histocompatibility complex by Viken, M K, Blomhoff, A, Olsson, M, Akselsen, H E, Pociot, F, Nerup, J, Kockum, I, Cambon-Thomsen, A, Thorsby, E, Undlien, D E, Lie, B A

“…The high-risk human leukocyte antigen ( HLA ) -DRB1 , DQA1 and DQB1 alleles cannot explain the entire type 1 diabetes (T1D) association observed within the…”
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Conditional analyses on the T1DGC MHC dataset: novel associations with type 1 diabetes around HLA-G and confirmation of HLA-B by Eike, M C, Becker, T, Humphreys, K, Olsson, M, Lie, B A

“…The major histocompatibility complex (MHC) is known to harbour genetic risk factors for type 1 diabetes (T1D) additional to the class II determinants HLA-DRB1…”
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Exploring the CLEC16A gene reveals a MS-associated variant with correlation to the relative expression of CLEC16A isoforms in thymus by Mero, I-L, Ban, M, Lorentzen, Å R, Smestad, C, Celius, E G, Sæther, H, Saeedi, H, Viken, M K, Skinningsrud, B, Undlien, D E, Aarseth, J, Myhr, K-M, Granum, S, Spurkland, A, Sawcer, S, Compston, A, Lie, B A, Harbo, H F

“…Genomewide association studies have implicated the CLEC16A gene in several autoimmune diseases, including multiple sclerosis (MS) and type 1 diabetes. However,…”
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CIITA gene variants are associated with rheumatoid arthritis in Scandinavian populations by Eike, M C, Skinningsrud, B, Ronninger, M, Stormyr, A, Kvien, T K, Joner, G, Njølstad, P R, Førre, Ø, Flatø, B, Alfredsson, L, Padyukov, L, Undlien, D E, Lie, B A

“…Expression of the major autoimmune risk loci DRB1 and DQB1 is regulated by the class II MHC (major histocompatibility complex) transactivator (CIITA), making…”
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Association analysis of the CCL3L1 copy number locus by paralogue ratio test in Norwegian rheumatoid arthritis patients and healthy controls by Nordang, G B N, Carpenter, D, Viken, M K, Kvien, T K, Armour, J A L, Lie, B A

“…Genotyping of multiallelic copy number variants (CNVs) is technically difficult and can lead to inaccurate conclusions. This is reflected by inconsistent…”
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Different HLA class II associations in ulcerative colitis patients with and without primary sclerosing cholangitis by Karlsen, T H, Boberg, K M, Vatn, M, Bergquist, A, Hampe, J, Schrumpf, E, Thorsby, E, Schreiber, S, Lie, B A

“…Approximately 80% of patients with primary sclerosing cholangitis (PSC) of Northern European origin have inflammatory bowel disease (IBD), the majority…”
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Association study of IL2/IL21 and FcgRIIa: significant association with the IL2/IL21 region in Scandinavian coeliac disease families by Adamovic, S, Amundsen, S S, Lie, B A, Gudjónsdóttir, A H, Ascher, H, Ek, J, van Heel, D A, Nilsson, S, Sollid, L M, Torinsson Naluai, Å

“…The first genome-wide association study performed in a UK coeliac disease (CD) case-control cohort revealed association with a linkage disequilibrium block…”
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Four novel coeliac disease regions replicated in an association study of a Swedish-Norwegian family cohort by Amundsen, S S, Rundberg, J, Adamovic, S, Gudjónsdóttir, A H, Ascher, H, Ek, J, Nilsson, S, Lie, B A, Naluai, Å T, Sollid, L M

“…Recent genome-wide association studies have identified 1q31 ( RGS1 ), 2q11–12 ( IL18RAP ), 3p21 ( CCR1/CCR3/CCR2 ), 3q25–26 ( IL12A/SCHIP1 ), 3q28 ( LPP ),…”
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Genetic variants of the HLA-A, HLA-B and AIF1 loci show independent associations with type 1 diabetes in Norwegian families by Eike, M C, Olsson, M, Undlien, D E, Dahl-Jørgensen, K, Joner, G, Rønningen, K S, Thorsby, E, Lie, B A

“…The main genetic predisposition to type 1 diabetes (T1D) is known to be conferred by the HLA-DRB1 , -DQA1 and -DQB1 genes in the major histocompatibility…”
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Genes in the HLA class I region may contribute to the HLA class II-associated genetic susceptibility to multiple sclerosis by Harbo, H.F., Lie, B.A., Sawcer, S., Celius, E.G., Dai, K.-Z., Oturai, A., Hillert, J., Lorentzen, Å.R., Laaksonen, M., Myhr, K.-M., Ryder, L.P., Fredrikson, S., Nyland, H., Sørensen, P.S., Sandberg-Wollheim, M., Andersen, O., Svejgaard, A., Edland, A., Mellgren, S.I., Compston, A., Vartdal, F., Spurkland, A.

“…: In order to analyze whether loci in the human leukocyte antigen (HLA) class I region may contribute to the HLA class II‐associated genetic susceptibility to…”
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Genetic analysis of the CD28/CTLA4/ICOS (CELIAC3) region in coeliac disease by Amundsen, S.S., Naluai, Å.T., Ascher, H., Ek, J., Gudjónsdóttir, A.H., Wahlström, J., Lie, B.A., Sollid, L.M.

“…:  In order to extend our previous findings of genetic linkage to the CD28/CTLA4/ICOS region on chromosome 2q33 (CELIAC3) in coeliac disease (CD), we have…”
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A gene telomeric of the HLA class I region is involved in predisposition to both type 1 diabetes and coeliac disease by Lie, B.A., Sollid, L.M., Ascher, H., Ek, J., Akselsen, H.E., Rønningen, K.S., Thorsby, E., Undlien, D.E.

“…We have recently shown that an as yet unidentified gene within or in the vicinity of the HLA complex, in linkage disequilibrium with microsatellite D6S2223,…”
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HLA in coeliac disease families: A novel test of risk modification by the 'other' haplotype when at least one DQA105-DQB102 haplotype is carried by Louka, A.S., Nilsson, S., Olsson, M., Talseth, B., Lie, B.A., Ek, J., Gudjónsdóttir, A.H., Ascher, H., Sollid, L.M.

“…: Predisposition to coeliac disease (CD) involves HLA genes. We investigated whether any haplotypes modify risk when carried trans to a known high‐risk…”
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