Search Results - "Liddle, P F"

Biological vulnerability to depression: linked structural and functional brain network findings by Nixon, N. L., Liddle, P. F., Nixon, E., Worwood, G., Liotti, M., Palaniyappan, L.

“…Patients in recovery following episodes of major depressive disorder (MDD) remain highly vulnerable to future recurrence. Although psychological determinants…”
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Reality distortion is related to the structure of the salience network in schizophrenia by Palaniyappan, L, Mallikarjun, P, Joseph, V, White, T P, Liddle, P F

“…An intrinsic cerebral network comprising the anterior cingulate and anterior insula (the salience network) is considered to play an important role in salience…”
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Resting-state functional connectivity correlates of anxiety co-morbidity in major depressive disorder by Briley, PM, Webster, L., Boutry, C., Cottam, WJ, Auer, DP, Liddle, PF, Morriss, R.

“…Major depressive disorder (MDD) is frequently co-morbid with anxiety disorders. The co-morbid state has poorer functional outcomes and greater resistance to…”
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Trajectories of improvement with repetitive transcranial magnetic stimulation for treatment-resistant major depression in the BRIGhTMIND trial by Briley, P M, Webster, L, Lankappa, S, Pszczolkowski, S, McAllister-Williams, R H, Liddle, P F, Auer, D P, Morriss, R

“…Repetitive transcranial magnetic stimulation (rTMS) is an established non-invasive brain stimulation treatment for major depressive disorder, but there is…”
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Prefrontal cortex function in remitted major depressive disorder by Nixon, N L, Liddle, P F, Worwood, G, Liotti, M, Nixon, E

“…Recent models of major depressive disorder (MDD) have proposed the rostral anterior cingulate (rACC) and dorsomedial prefrontal cortex (dmPFC) as nexus sites…”
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Surface anatomical profile of the cerebral cortex in obsessive-compulsive disorder: a study of cortical thickness, folding and surface area by Fan, Q, Palaniyappan, L, Tan, L, Wang, J, Wang, X, Li, C, Zhang, T, Jiang, K, Xiao, Z, Liddle, P F

“…Studying the distribution of anatomical abnormalities over the entire cortical surface can help to identify key neural circuits implicated in generating…”
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Gyrification of Broca's region is anomalously lateralized at onset of schizophrenia in adolescence and regresses at 2 year follow-up by Palaniyappan, L, Crow, T.J, Hough, M, Voets, N.L, Liddle, P.F, James, S, Winmill, L, James, A.C

“…Abstract Gyrification of the human cerebral cortex starts in the foetus and progresses in early infancy; the pattern of folding in later life provides a lead…”
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Reversed lateralization of temporal activation during speech production in thought disordered patients with schizophrenia by Kircher, T T J, Liddle, P F, Brammer, M J, Williams, S C R, Murray, R M, McGuire, P K

“…Formal thought disorder is a core symptom of schizophrenia. It is associated with a reversed lateralization of the superior temporal cortex volume, an area…”
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Task induced modulation of neural oscillations in electrophysiological brain networks by Brookes, M.J., Liddle, E.B., Hale, J.R., Woolrich, M.W., Luckhoo, H., Liddle, P.F., Morris, P.G.

“…In recent years, one of the most important findings in systems neuroscience has been the identification of large scale distributed brain networks. These…”
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Cognitive deficits in early-onset schizophrenia spectrum patients and their non-psychotic siblings: A comparison with ADHD by Groom, M.J, Jackson, G.M, Calton, T.G, Andrews, H.K, Bates, A.T, Liddle, P.F, Hollis, C

“…Abstract Background Previous research has shown cognitive deficits in patients with schizophrenia spectrum disorders in the areas of executive function, verbal…”
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Functional connectivity: the principal-component analysis of large (PET) data sets by Friston, K J, Frith, C D, Liddle, P F, Frackowiak, R S

“…The distributed brain systems associated with performance of a verbal fluency task were identified in a nondirected correlational analysis of…”
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Inefficient cerebral recruitment as a vulnerability marker for schizophrenia by Liddle, E B, Bates, A T, Das, D, White, T P, Groom, M J, Jansen, M, Jackson, G M, Hollis, C, Liddle, P F

“…Patients with schizophrenia and their first-degree relatives exhibit both abnormally diminished and increased neural activation during cognitive tasks. In…”
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Error processing and the rostral anterior cingulate: An event-related fMRI study by KIEHL, KENT A., LIDDLE, PETER F., HOPFINGER, JOSEPH B.

“…The anterior cingulate is believed to play a crucial role in the regulation of thought and action. Recent evidence suggests that the anterior cingulate may…”
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Dysfunction of a distributed neural circuitry in schizophrenia patients during a working-memory performance by Mendrek, A, Kiehl, K A, Smith, A M, Irwin, D, Forster, B B, Liddle, P F

“…In a recent longitudinal study of first-episode schizophrenia patients, we found that while dysfunction of the right dorsolateral prefrontal cortex (DLPFC),…”
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Changes in distributed neural circuitry function in patients with first-episode schizophrenia by Mendrek, A., Laurens, K. R., Kiehl, K. A., Ngan, E. T. C., Stip, E., Liddle, P. F.

“…A number of functional brain abnormalities have been reported in schizophrenia, but it remains to be determined which of them represent trait and state markers…”
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The genetics of symptom dimensions of schizophrenia: Review and meta-analysis by Rietkerk, T, Boks, M.P.M, Sommer, I.E, Liddle, P.F, Ophoff, R.A, Kahn, R.S

“…Abstract Background The use of symptom dimensions of schizophrenia as quantitative phenotypes has been proposed as a mean to reduce the heterogeneity of…”
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Neurological soft signs discriminating mood disorders from first episode schizophrenia by Boks, M. P. M., Liddle, P. F., Burgerhof, J. G. M., Knegtering, R., van den Bosch, R.-J.

“…Objective:  To investigate the specificity of neurological soft signs (NSS) for first episode schizophrenia compared with mood disorders. Method:  We assessed…”
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Comparing functional (PET) images: the assessment of significant change by Friston, K J, Frith, C D, Liddle, P F, Frackowiak, R S

“…Statistical parametric maps (SPMs) are potentially powerful ways of localizing differences in regional cerebral activity. This potential is limited by…”
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Dynamic cerebral reorganization in the pathophysiology of schizophrenia: a MRI-derived cortical thickness study by Guo, S, Palaniyappan, L, Liddle, P F, Feng, J

“…A structural neuroanatomical change indicating a reduction in brain tissue is a notable feature of schizophrenia. Several pathophysiological processes such as…”
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Regional brain activity in chronic schizophrenic patients during the performance of a verbal fluency task by Frith, C D, Friston, K J, Herold, S, Silbersweig, D, Fletcher, P, Cahill, C, Dolan, R J, Frackowiak, R S, Liddle, P F

“…This study examined the pattern of cerebral blood flow observed in chronic schizophrenic patients while they performed a paced verbal fluency task. Such tasks…”
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