Search Results - "Lidén, Martin"

Retinol-binding protein-4 attenuates insulin-induced phosphorylation of IRS1 and ERK1/2 in primary human adipocytes by Öst, Anita, Danielsson, Anna, Lidén, Martin, Eriksson, Ulf, Nystrom, Fredrik H, Strålfors, Peter

“…Reduced sensitivity to insulin in adipose, muscle, and liver tissues is a hallmark of type 2 diabetes. Animal models and patients with type 2 diabetes exhibit…”
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Activation of Innate Immunity, Inflammation, and Potentiation of DNA Vaccination through Mammalian Expression of the TLR5 Agonist Flagellin by Applequist, Steven E, Rollman, Erik, Wareing, Mark D, Liden, Martin, Rozell, Bjorn, Hinkula, Jorma, Ljunggren, Hans-Gustaf

“…Improving DNA vaccination remains a fundamental goal in vaccine research. Theoretically, this could be achieved by molecules encoded by DNA capable of…”
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Understanding Retinol Metabolism: Structure and Function of Retinol Dehydrogenases by Lidén, Martin, Eriksson, Ulf

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Structure and function of retinol dehydrogenases of the short chain dehydrogenase/reductase family by Lidén, Martin, Tryggvason, Kristian, Eriksson, Ulf

“…All- trans-retinol is the common precursor of the active retinoids 11- cis-retinal, all- trans-retinoic acid (atRA) and 9- cis-retinoic acid (9cRA). Genetic…”
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Development of a versatile reporter assay for studies of retinol uptake and metabolism in vivo by Lidén, Martin, Eriksson, Ulf

“…The two isomers of retinoic acid (RA), all-trans RA and 9-cis RA, are produced in several tissues in order to allow specific control of target gene…”
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The C-terminal region of cis-retinol/androgen dehydrogenase 1 (CRAD1) confers ER localization and in vivo enzymatic function by Lidén, Martin, Tryggvason, Kristian, Eriksson, Ulf

“…Retinoic acid is generated from retinol (vitamin A) by the sequential actions of two different classes of enzymes, retinol dehydrogenases and retinal…”
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Biochemical Defects in 11-cis-Retinol Dehydrogenase Mutants Associated with Fundus Albipunctatus by Lidén, Martin, Romert, Anna, Tryggvason, Kristian, Persson, Bengt, Eriksson, Ulf

“…Mutations in the gene encoding 11-cis-retinol dehydrogenase (RDH5; EC 1.1.1.105) are associated with fundus albipunctatus, an autosomal recessive eye disease…”
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Molecular Aspects of Retinol Uptake and Activation by Lidén, Martin

“…Retinoids (vitamin A derivatives) are essential for a wide variety ofphysiological processes, including embryonic development, growth, vision,reproduction, and…”
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