Search Results - "Lichtman, Stuart M"
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Practical Assessment and Management of Vulnerabilities in Older Patients Receiving Chemotherapy: ASCO Guideline for Geriatric Oncology
Published in Journal of clinical oncology (01-08-2018)“…Purpose To provide guidance regarding the practical assessment and management of vulnerabilities in older patients undergoing chemotherapy. Methods An Expert…”
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Broadening Eligibility Criteria to Make Clinical Trials More Representative: American Society of Clinical Oncology and Friends of Cancer Research Joint Research Statement
Published in Journal of clinical oncology (20-11-2017)“…Purpose The primary purposes of eligibility criteria are to protect the safety of trial participants and define the trial population. Excessive or overly…”
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Predicting Chemotherapy Toxicity in Older Adults With Cancer: A Prospective Multicenter Study
Published in Journal of clinical oncology (01-09-2011)“…Older adults are vulnerable to chemotherapy toxicity; however, there are limited data to identify those at risk. The goals of this study are to identify risk…”
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End Points and Trial Design in Geriatric Oncology Research: A Joint European Organisation for Research and Treatment of Cancer–Alliance for Clinical Trials in Oncology–International Society of Geriatric Oncology Position Article
Published in Journal of clinical oncology (10-10-2013)“…Selecting the most appropriate end points for clinical trials is important to assess the value of new treatment strategies. Well-established end points for…”
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Long-term Toxicity of Cancer Treatment in Older Patients
Published in Clinics in geriatric medicine (01-02-2016)“…With earlier cancer diagnosis among older patients with cancer, the possibility of curing cancer increases. However, cancer treatment may have a long-lasting…”
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Breast and ovarian cancer in the older woman
Published in Journal of clinical oncology (20-08-2014)“…Nearly half of all women diagnosed with breast or ovarian cancer are age 65 years or older with the number of women diagnosed expected to increase as the…”
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International Society of Geriatric Oncology Chemotherapy Taskforce: Evaluation of Chemotherapy in Older Patients—An Analysis of the Medical Literature
Published in Journal of clinical oncology (10-05-2007)“…The elderly comprise the majority of patients with cancer and are the recipients of the greatest amount of chemotherapy. Unfortunately, there is a lack of data…”
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Clinical Trial Endpoints in Metastatic Cancer: Using Individual Participant Data to Inform Future Trials Methodology
Published in JNCI : Journal of the National Cancer Institute (13-06-2022)“…Abstract Meta-analysis based on individual participant data (IPD) is a powerful methodology for synthesizing evidence by combining information drawn from…”
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Distress in Older Patients With Cancer
Published in Journal of clinical oncology (10-09-2009)“…To determine the predictors of distress in older patients with cancer. Patients age >or= 65 years with a solid tumor or lymphoma completed a questionnaire that…”
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A novel approach to improve health status measurement in observational claims-based studies of cancer treatment and outcomes
Published in Journal of geriatric oncology (01-04-2013)“…Abstract Objectives To develop and provide initial validation for a multivariate, claims-based prediction model for disability status (DS), a proxy measure of…”
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Missed Opportunities in Geriatric Oncology Research
Published in The oncologist (Dayton, Ohio) (01-05-2023)“…Abstract The field of geriatric oncology has made significant progress in recent decades, but there are still missed opportunities in important areas of…”
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Chemotherapy of ovarian cancer in elderly patients
Published in Cancer biology & medicine (01-12-2015)“…Epithelial ovarian cancer is primarily a disease of older women. Advanced age is risk factor for decreased survival. Optimal surgery and the safe and effective…”
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Systemic therapy of non-colorectal gastrointestinal malignancies in the elderly
Published in Cancer biology & medicine (01-12-2015)“…In the coming years life expectancy is expected to increase and with this the percentage of the population above age 65 will grow. Patients above 65 make up…”
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Clinical Cancer Advances 2012: Annual Report on Progress Against Cancer From the American Society of Clinical Oncology
Published in Journal of clinical oncology (01-01-2013)“…A MESSAGE FROM ASCO'S PRESIDENT I am delighted to present you with “Clinical Cancer Advances 2012: Annual Report on Progress Against Cancer From the American…”
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Patterns of first recurrence following adjuvant intraperitoneal chemotherapy for stage IIIC ovarian cancer
Published in Gynecologic oncology (01-01-2012)“…Abstract Objective Adjuvant intraperitoneal (IP) platinum-based chemotherapy has been shown to improve outcome for patients with advanced ovarian cancer. We…”
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The prophylactic conversion to an extended infusion schedule and use of premedication to prevent hypersensitivity reactions in ovarian cancer patients during carboplatin retreatment
Published in Gynecologic oncology (01-03-2010)“…Abstract Objective Repeated exposure to carboplatin can lead to hypersensitivity reactions during retreatment with carboplatin. This may prevent its further…”
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Initiation and termination of dialysis in older patients with advanced cancer: providing guidance in a complicated situation
Published in The Lancet. Healthy longevity (01-01-2021)“…Cancer and chronic kidney disease prevalence both increase with age. As a consequence, physicians are more frequently encountering older people with cancer who…”
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Pharmacokinetics of chemotherapy in the older patient
Published in Cancer control (01-01-2007)“…The number of individuals aged 65 years and older is growing rapidly, and the majority of cancers are diagnosed in this age group. Age-related changes in…”
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Phase I and Pharmacokinetic Study of Erlotinib for Solid Tumors in Patients With Hepatic or Renal Dysfunction: CALGB 60101
Published in Journal of clinical oncology (20-07-2007)“…We investigated dose and pharmacokinetics of erlotinib in patients with hepatic dysfunction or renal dysfunction. Patients were assigned to one of three…”
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Improving the Evidence Base for Treating Older Adults With Cancer: American Society of Clinical Oncology Statement
Published in Journal of clinical oncology (10-11-2015)“…The American Society of Clinical Oncology (ASCO) convened a subcommittee to develop recommendations on improving the evidence base for treating older adults…”
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