Search Results - "Lichtfuss, Gregor"

HIV infection induces age-related changes to monocytes and innate immune activation in young men that persist despite combination antiretroviral therapy by HEARPS, Anna C, MAISA, Anna, CHENG, Wan-Jung, ANGELOVICH, Thomas A, LICHTFUSS, Gregor F, PALMER, Clovis S, LANDAY, Alan L, JAWOROWSKI, Anthony, CROWE, Suzanne M

“…To compare the impact of HIV infection and healthy ageing on monocyte phenotype and function and determine whether age-related changes induced by HIV are…”
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Virologically suppressed HIV patients show activation of NK cells and persistent innate immune activation by Lichtfuss, Gregor F, Cheng, Wan-Jung, Farsakoglu, Yagmur, Paukovics, Geza, Rajasuriar, Reena, Velayudham, Pushparaj, Kramski, Marit, Hearps, Anna C, Cameron, Paul U, Lewin, Sharon R, Crowe, Suzanne M, Jaworowski, Anthony

“…FcRγ is an ITAM-containing adaptor required for CD16 signaling and function in NK cells. We have previously shown that NK cells from HIV patients receiving…”
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First‐in‐human clinical trial of allogeneic, platelet‐derived extracellular vesicles as a potential therapeutic for delayed wound healing by Johnson, Jancy, Law, Sam Q. K., Shojaee, Mozhgan, Hall, Alex S., Bhuiyan, Sadman, Lim, Melissa B. L., Silva, Anabel, Kong, Karmen J. W., Schoppet, Melanie, Blyth, Chantelle, Ranasinghe, Hansi N., Sejic, Nenad, Chuei, Mun Joo, Tatford, Owen C., Cifuentes‐Rius, Anna, James, Patrick F., Tester, Angus, Dixon, Ian, Lichtfuss, Gregor

“…The release of growth factors, cytokines and extracellular matrix modifiers by activated platelets is an important step in the process of healthy wound…”
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Viremic and Virologically Suppressed HIV Infection Increases Age-Related Changes to Monocyte Activation Equivalent to 12 and 4 Years of Aging, Respectively by Angelovich, Thomas A, Hearps, Anna C, Maisa, Anna, Martin, Genevieve E, Lichtfuss, Gregor F, Cheng, Wan-Jung, Palmer, Clovis S, Landay, Alan L, Crowe, Suzanne M, Jaworowski, Anthony

“…Chronic inflammation and immune activation occur in both HIV infection and normal aging and are associated with inflammatory disease. However, the degree to…”
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HIV inhibits early signal transduction events triggered by CD16 cross-linking on NK cells, which are important for antibody-dependent cellular cytotoxicity by Lichtfuss, Gregor F., Meehan, Aislin C., Cheng, Wan‐Jung, Cameron, Paul U., Lewin, Sharon R., Crowe, Suzanne M., Jaworowski, Anthony

“…Defective NK cell ADCC in whole blood from HIV‐infected patients due to impaired early signaling in response to CD16 surface receptor cross‐linking…”
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Biomarkers of immune dysfunction following combination antiretroviral therapy for HIV infection by Lichtfuss, Gregor F, Hoy, Jennifer, Rajasuriar, Reena, Kramski, Marit, Crowe, Suzanne M, Lewin, Sharon R

“…Combination antiretroviral therapy (cART) has significantly reduced morbidity and mortality of HIV-infected patients, yet their life expectancy remains reduced…”
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Anti‐HIV‐1 antibody‐dependent cellular cytotoxicity mediated by hyperimmune bovine colostrum IgG by Kramski, Marit, Lichtfuss, Gregor F., Navis, Marjon, Isitman, Gamze, Wren, Leia, Rawlin, Grant, Center, Rob J., Jaworowski, Anthony, Kent, Stephen J., Purcell, Damian F. J.

“…Antibodies with antibody‐dependent cellular cytotoxicity (ADCC) activity play an important role in protection against HIV‐1 infection, but generating…”
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Rapid detection of anti-Vaccinia virus neutralizing antibodies by Kramski, Marit, Drozd, Anna, Lichtfuss, Gregor F, Dabrowski, Piotr W, Ellerbrok, Heinz

“…Increasing infections with Monkeypox and Cowpox viruses pose a continuous and growing threat to human health. The standard method for detecting poxvirus…”
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Prospective Therapeutic Applications of Platelet Extracellular Vesicles by Johnson, Jancy, Wu, Yu-Wen, Blyth, Chantelle, Lichtfuss, Gregor, Goubran, Hadi, Burnouf, Thierry

“…There is much interest in the use of extracellular vesicles (EVs) as a subcellular therapy for regenerative medicine and drug delivery. Blood-borne platelets…”
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Microfluidic resistive pulse sensing (MRPS) validated as a rapid and practical method for evaluating EV enrichment techniques by Fraikin, Jean-Luc, Johnson, Jancy, Dixon, Ian, Kalionis, Bill, Lichtfuss, Gregor

“…Background: Delivering commercial value for extracellular vesicles (EVs) as therapeutics requires improved techniques for their isolation and enrichment…”
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Anti‐ HIV ‐1 antibody‐dependent cellular cytotoxicity mediated by hyperimmune bovine colostrum I g G by Kramski, Marit, Lichtfuss, Gregor F., Navis, Marjon, Isitman, Gamze, Wren, Leia, Rawlin, Grant, Center, Rob J., Jaworowski, Anthony, Kent, Stephen J., Purcell, Damian F. J.

“…Antibodies with antibody‐dependent cellular cytotoxicity ( ADCC ) activity play an important role in protection against HIV ‐1 infection, but generating…”
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Characterization of extracellular vesicles derived from two populations of human placenta derived mesenchymal stem/stromal cells by Khanabdali, R., Shojaee, M., Johnson, J., Law, S., Whitmore, M., Lim, M., Schoppet, M., Silva, A., James, P., Kalionis, B., Dixon, I., Lichtfuss, G. Gregor, Tester, A.

“…Growing evidence shows that extracellular vesicles (EVs) are responsible for the therapeutic effect of stem cell therapy. EVs are a promising, potential…”
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