Search Results - "Lichtenhan, J. T."

Direct administration of 2-Hydroxypropyl-Beta-Cyclodextrin into guinea pig cochleae: Effects on physiological and histological measurements by Lichtenhan, J T, Hirose, K, Buchman, C A, Duncan, R K, Salt, A N

“…2-Hydroxypropyl-Beta-Cyclodextrin (HPβCD) can be used to treat Niemann-Pick type C disease, Alzheimer's disease, and atherosclerosis. But, a consequence is…”
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Altered mapping of sound frequency to cochlear place in ears with endolymphatic hydrops provide insight into the pitch anomaly of diplacusis by Guinan, J. J., Lefler, S. M., Buchman, C. A., Goodman, S. S., Lichtenhan, J. T.

“…A fundamental property of mammalian hearing is the conversion of sound pressure into a frequency-specific place of maximum vibration along the cochlear length,…”
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Early Detection of Endolymphatic Hydrops using the Auditory Nerve Overlapped Waveform (ANOW) by Lee, C., Valenzuela, C.V., Goodman, S.S., Kallogjeri, D., Buchman, C.A., Lichtenhan, J.T.

“…•Endolymphatic hydrops (EH) is associated with low-frequency hearing loss (LFSNHL).•The cause of the LFSNHL is still unknown.•In the early days after inducing…”
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Medial olivocochlear efferent reflex inhibition of human cochlear nerve responses by Lichtenhan, J.T., Wilson, U.S., Hancock, K.E., Guinan, J.J.

“…Inhibition of cochlear amplifier gain by the medial olivocochlear (MOC) efferent system has several putative roles: aiding listening in noise, protection…”
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Drug delivery into the cochlear apex: Improved control to sequentially affect finely spaced regions along the entire length of the cochlear spiral by Lichtenhan, J.T., Hartsock, J., Dornhoffer, J.R., Donovan, K.M., Salt, A.N.

“…•A new method to pharmacologically affect the cochlea is described.•Solutions are administered from a pipette sealed into the cochlear apex.•Controlled…”
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The influence of noise exposure on the parameters of a convolution model of the compound action potential by Chertoff, M. E., Lichtenhan, J. T., Tourtillott, B. M., Esau, K. S.

“…The influence of noise exposure on the parameters of a convolution model of the compound action potential (CAP) was examined. CAPs were recorded in…”
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Cochlear compound action potentials from high-level tone bursts originate from wide cochlear regions that are offset toward the most sensitive cochlear region by Lee, C, Guinan, Jr, J J, Rutherford, M A, Kaf, W A, Kennedy, K M, Buchman, C A, Salt, A N, Lichtenhan, J T

“…Little is known about the spatial origins of auditory nerve (AN) compound action potentials (CAPs) evoked by moderate to intense sounds. We studied the spatial…”
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An analysis of cochlear response harmonics: Contribution of neural excitation by Chertoff, M E, Kamerer, A M, Peppi, M, Lichtenhan, J T

“…In this report an analysis of cochlear response harmonics is developed to derive a mathematical function to estimate the gross mechanics involved in the in…”
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The Auditory Nerve Overlapped Waveform (ANOW) Originates in the Cochlear Apex by Lichtenhan, J. T., Hartsock, J. J., Gill, R. M., Guinan, J. J., Salt, A. N.

“…Measurements of cochlear function with compound action potentials (CAPs), auditory brainstem responses, and otoacoustic emissions work well with high-frequency…”
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Influence of hearing sensitivity on mechano-electric transduction by Chertoff, Mark E, Yi, Xing, Lichtenhan, Jeffery T

“…This study examined the relation between the extent of permanent hearing loss and the change in a third-order polynomial transducer function (PTF) representing…”
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Behavioral Pure-Tone Threshold Shifts Caused by Tympanic Membrane Electrodes by Smith, Spencer B., Lichtenhan, Jeffery, Cone, Barbara

“…OBJECTIVE:To determine whether tympanic membrane (TM) electrodes induce behavioral pure-tone threshold shifts. DESIGN:Pure-tone thresholds (250 to 8000 Hz)…”
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Predicting severity of cochlear hair cell damage in adult chickens using DPOAE input–output functions by Lichtenhan, Jeffery T., Chertoff, Mark E., Smittkamp, Susan E., Durham, Dianne, Girod, Douglas A.

“…Distortion product otoacoustic emissions (DPOAE) were recorded from the ear canal of aged broiler chickens which have been shown to present with age-related…”
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