Search Results - "Lichte, A."
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Matrix Metalloproteinases Collagenase-2, Macrophage Elastase, Collagenase-3, and Membrane Type 1-Matrix Metalloproteinase Impair Clotting by Degradation of Fibrinogen and Factor XII
Published in The Journal of biological chemistry (20-10-2000)“…The effects of plasma proteins on controlling the activity of matrix metalloproteinases (MMPs, matrixins) have been the focus of numerous studies, although…”
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Crystal structure of the complex formed by the membrane type 1-matrix metalloproteinase with the tissue inhibitor of metalloproteinases-2, the soluble progelatinase A receptor
Published in The EMBO journal (01-09-1998)“…The proteolytic activity of matrix metalloproteinases (MMPs) towards extracellular matrix components is held in check by the tissue inhibitors of…”
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The recombinant catalytic domain of membrane-type matrix metalloproteinase-1 (MT1-MMP) induces activation of progelatinase A and progelatinase A complexed with TIMP-2
Published in FEBS letters (18-11-1996)“…A truncated form of the membrane-type matrix metalloproteinase-1 [(Ala 21-Ile 318)proMT1-MMP] lacking the hemopexin-like and trans-membrane domain was produced…”
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Membrane type 1 matrix metalloproteinase (MT1-MMP) cleaves the recombinant aggrecan substrate rAgg1mut at the 'aggrecanase' and the MMP sites. Characterization of MT1-MMP catabolic activities on the interglobular domain of aggrecan
Published in Biochemical journal (01-07-1998)“…The recent detection of membrane type 1 matrix metalloproteinase (MT1-MMP) expression in human articular cartilage [Büttner, Chubinskaya, Margerie, Huch,…”
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Internal super(32)P-labeling of L-deoxyoligonucleotides
Published in Nucleic acids research (01-04-2003)“…A general two step procedure for the internal labeling of L- deoxyoligonucleotides, Spiegelmers, has been developed. Through radioactive labeling…”
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Identification of the Active Site of Gelatinase B as the Structural Element Sufficient for Converting a Protein to a Metalloprotease
Published in Biochemistry (Easton) (16-04-2002)“…Gelatinase B is a member of the matrix metalloproteinase family that efficiently cleaves gelatin, elastin, and types V and X collagen. To understand the…”
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GnRH Binding RNA and DNA Spiegelmers: A Novel Approach toward GnRH Antagonism
Published in Chemistry & biology (01-03-2002)“…Mirror-image oligonucleotide ligands (Spiegelmers) that bind to the pharmacologically relevant target gonadotropin-releasing hormone I (GnRH) with high…”
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