Search Results - "Licht, Alexander H."

Phenolic excipients of insulin formulations induce cell death, pro-inflammatory signaling and MCP-1 release by Weber, Claudia, Kammerer, Daniel, Streit, Bettina, Licht, Alexander H

“…Skin reactions at the infusion site are a common side effect of continuous subcutaneous insulin infusion therapy. We hypothesized that local skin complications…”
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Inhibition of hypoxia-inducible factor activity in endothelial cells disrupts embryonic cardiovascular development by Licht, Alexander H., Müller-Holtkamp, Felix, Flamme, Ingo, Breier, Georg

“…Hypoxia-inducible factors (HIFs) are transcriptional regulators that mediate the cellular response to low oxygen levels. By stimulating the expression of…”
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JunB is required for endothelial cell morphogenesis by regulating core-binding factor β by Licht, Alexander H, Pein, Oliver T, Florin, Lore, Hartenstein, Bettina, Reuter, Hendrik, Arnold, Bernd, Lichter, Peter, Angel, Peter, Schorpp-Kistner, Marina

“…The molecular mechanism triggering the organization of endothelial cells (ECs) in multicellular tubules is mechanistically still poorly understood. We…”
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JunB Is Required for IgE-Mediated Degranulation and Cytokine Release of Mast Cells by Textor, Bjorn, Licht, Alexander H, Tuckermann, Jan P, Jessberger, Rolf, Razin, Ehud, Angel, Peter, Schorpp-Kistner, Marina, Hartenstein, Bettina

“…Mast cells are effector cells of IgE-mediated immune responses frequently found at the vicinity of blood vessels, the margins of diverse tumors and at sites of…”
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Endothelium‐specific Cre recombinase activity in flk‐1‐Cre transgenic mice by Licht, Alexander H., Raab, Sabine, Hofmann, Ursula, Breier, Georg

“…The use of the Cre‐loxP recombination system allows the conditional inactivation of genes in mice. The availability of transgenic mice in which the Cre…”
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Insulin induces a progressive increase in the resistance of subcutaneous tissue to fluid flow: Implications for insulin pump therapy by Regittnig, Werner, Tschaikner, Mathias, Tuca, Alexandru‐Cristian, Simic, Amra, Feiel, Jürgen, Schaller‐Ammann, Roland, Licht, Alexander H., Jungklaus, Miró, Pieber, Thomas R.

“…Aim To determine the effect of insulin on the resistance of subcutaneous tissue to the flow of infusion fluids. Materials and methods Thirty subjects with type…”
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Critical role for NF-κB-induced JunB in VEGF regulation and tumor angiogenesis by Schmidt, Dirk, Textor, Björn, Pein, Oliver T, Licht, Alexander H, Andrecht, Sven, Sator-Schmitt, Melanie, Fusenig, Norbert E, Angel, Peter, Schorpp-Kistner, Marina

“…Regulation of vascular endothelial growth factor (VEGF) expression is a complex process involving a plethora of transcriptional regulators. The AP‐1…”
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Junb regulates arterial contraction capacity, cellular contractility, and motility via its target Myl9 in mice by Licht, Alexander H, Nübel, Tobias, Feldner, Anja, Jurisch-Yaksi, Nathalie, Marcello, Marco, Demicheva, Elena, Hu, Jun-Hao, Hartenstein, Bettina, Augustin, Hellmut G, Hecker, Markus, Angel, Peter, Korff, Thomas, Schorpp-Kistner, Marina

“…Cellular contractility and, thus, the ability to alter cell shape are prerequisites for a number of important biological processes such as cytokinesis,…”
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HIF in vascular development and tumour angiogenesis by Breier, Georg, Licht, Alexander H, Nicolaus, Anke, Klotzsche, Anne, Wielockx, Ben, Kirsnerova, Zuzana

“…Hypoxia stimulates angiogenesis through the up-regulation of vascular endothelial growth factor and other angiogenic cytokines. Members of the…”
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Inhibition of hypoxia-inducible factor activity in endothelial cells disrupts embryonic cardiovascular development. Commentary by SEMENZA, Gregg L, LICHT, Alexander H, MüLLER-HOLTKAMP, Felix, FLAMME, Ingo, BREIER, Georg

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Critical role for NF-kappaB-induced JunB in VEGF regulation and tumor angiogenesis by Schmidt, Dirk, Textor, Björn, Pein, Oliver T, Licht, Alexander H, Andrecht, Sven, Sator-Schmitt, Melanie, Fusenig, Norbert E, Angel, Peter, Schorpp-Kistner, Marina

“…Regulation of vascular endothelial growth factor (VEGF) expression is a complex process involving a plethora of transcriptional regulators. The AP-1…”
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Critical role for NF-[kappa]B-induced JunB in VEGF regulation and tumor angiogenesis by Schmidt, Dirk, Textor, Björn, Pein, Oliver T, Licht, Alexander H, Andrecht, Sven, Sator-Schmitt, Melanie, Fusenig, Norbert E, Angel, Peter, Schorpp-Kistner, Marina

“…Regulation of vascular endothelial growth factor (VEGF) expression is a complex process involving a plethora of transcriptional regulators. The AP-1…”
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JunB is required for endothelial cell morphogenesis by regulating core-binding factor [beta] by Licht, Alexander H, Pein, Oliver T, Lore Florin, Hartenstein, Bettina

“…The molecular mechanism triggering the organization of endothelial cells (ECs) in multicellular tubules is mechanistically still poorly understood. We…”
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