Search Results - "Licciardo, Paolo"

Transcriptional activity of positive transcription elongation factor b kinase in vivo requires the C-terminal domain of RNA polymerase II by Napolitano, Giuliana, Majello, Barbara, Licciardo, Paolo, Giordano, Anonio, Lania, Luigi

“…Phosphorylation of the carboxyl-terminal domain (CTD) of RNA polymerase II (RNAPII) is an important step in transcription and the positive transcription…”
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Identification of proteins interacting with the RNAPII FCP1 phosphatase: FCP1 forms a complex with arginine methyltransferase PRMT5 and it is a substrate for PRMT5-mediated methylation by Amente, Stefano, Napolitano, Giuliana, Licciardo, Paolo, Monti, Maria, Pucci, Piero, Lania, Luigi, Majello, Barbara

“…FCP1, a phosphatase specific of the carboxyl-terminal-domain of the large subunit of the RNA polymerase II (RNAPII), stimulates transcription elongation and it…”
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CDK9 has the intrinsic property to shuttle between nucleus and cytoplasm, and enhanced expression of CyclinT1 promotes its nuclear localization by Napolitano, Giuliana, Licciardo, Paolo, Carbone, Roberta, Majello, Barbara, Lania, Luigi

“…CDK9 in association with cyclin T constitutes the P‐TEFb complex that stimulates transcription elongation of RNAPII transcripts by phosphorylation of the CTD…”
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CDK9 has the intrinsic property to shuttle between nucleus and cytoplasm, and enhanced expression of cyclin T1 promotes its nuclear localization by Napolitano, Giuliana, Licciardo, Paolo, Carbone, Roberta, Majello, Barbara, Lania, Luigi

“…CDK9 in association with cyclin T constitutes the P-TEFb complex that stimulates transcription elongation of RNAPII transcripts by phosphorylation of the CTD…”
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The FCP1 phosphatase interacts with RNA polymerase II and with MEP50 a component of the methylosome complex involved in the assembly of snRNP by Licciardo, Paolo, Amente, Stefano, Ruggiero, Luca, Monti, Maria, Pucci, Piero, Lania, Luigi, Majello, Barbara

“…RNA polymerase II transcription is associated with cyclic phosphorylation of the C‐terminal domain (CTD) of the large subunit of RNA polymerase II. To date,…”
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Transcription activation by targeted recruitment of the RNA polymerase II CTD phosphatase FCP1 by Licciardo, P, Ruggiero, L, Lania, L, Majello, B

“…Human FCP1 in association with RNAP II reconstitutes a highly specific CTD phosphatase activity and is required for recycling RNA polymerase II (RNAP II) in…”
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The CDK9-associated cyclins T1 and T2 exert opposite effects on HIV-1 Tat activity by NAPOLITANO, G, LICCIARDO, P, GALLO, P, MAJELLO, B, GIORDANO, A, LANIA, L

“…To examine the functional interaction between HIV-1 Tat protein and the cyclin T1 and T2 proteins which, in association with cyclin dependent kinase (CDK)9,…”
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Zinc-α2-glycoprotein hinders cell proliferation and reduces cdc2 expression by He, Nonggao, Brysk, Henry, Tyring, Stephen K., Ohkubo, Iwao, Brysk, Miriam M.

“…Zinc‐α2‐glycoprotein (Znα2gp) is widely distributed in body fluids and epithelia. Its expression in stratified epithelia increases with differentiation. We…”
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Inhibition of Tat transactivation by the RNA polymerase II CTD-phosphatase FCP1 by LICCIARDO, Paolo, NAPOLITANO, Giuliana, MAJELLO, Barbara, LANIA, Luigi

“…To asses the role of the RNAPII carboxy-terminal domain (CTD) phosphatase FCP1 on HIV-1 Tat-mediated transactivation. Construction of expression vectors…”
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Distinct regions of cyclinT1 are required for binding to CDK9 and for recruitment to the HIV-1 Tat/TAR complex by Fraldi, Alessandro, Licciardo, Paolo, Majello, Barbara, Giordano, Antonio, Lania, Luigi

“…Tat‐mediated activation of the HIV‐1 promoter activity requires Tat‐dependent recruitment of the cyclinT1/CDK9 complex (P‐TEFb) to the transacting element…”
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