Search Results - "Libusova, Lenka"
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SWIP mediates retromer‐independent membrane recruitment of the WASH complex
Published in Traffic (Copenhagen, Denmark) (01-05-2023)“…The pentameric WASH complex facilitates endosomal protein sorting by activating Arp2/3, which in turn leads to the formation of F‐actin patches specifically on…”
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2
Human myotubularin-related protein 9 regulates ER-to-Golgi trafficking and modulates WNT3A secretion
Published in Experimental cell research (01-01-2020)“…Regulation of phosphatidylinositol phosphates plays a crucial role in signal transduction, membrane trafficking or autophagy. Members of the myotubularin…”
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3
N-cadherin can structurally substitute for E-cadherin during intestinal development but leads to polyp formation
Published in Development (Cambridge) (15-07-2010)“…We conditionally substituted E-cadherin (E-cad; cadherin 1) with N-cadherin (N-cad; cadherin 2) during intestine development by generating mice in which an…”
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4
Microtubule-targeting agents and their impact on cancer treatment
Published in European journal of cell biology (01-05-2020)“…•MTAs already have a prominent role in cancer treatment.•The two main problems associated with cancer therapy by MTAs are high systemic toxicity and…”
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5
Katanin activity in tau envelopes negatively correlates with ATP levels
Published in Biophysical journal (10-02-2023)Get full text
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Microtubule lattice spacing governs cohesive envelope formation of tau family proteins
Published in Nature chemical biology (01-11-2022)“…Tau is an intrinsically disordered microtubule-associated protein (MAP) implicated in neurodegenerative disease. On microtubules, tau molecules segregate into…”
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CKAP5 enables formation of persistent actin bundles templated by dynamically instable microtubules
Published in Current biology (22-01-2024)“…Cytoskeletal rearrangements and crosstalk between microtubules and actin filaments are vital for living organisms. Recently, an abundantly present microtubule…”
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8
N-cadherin can structurally substitute for E-cadherin during intestinal development but leads to polyp formation
Published in Journal of cell science (15-07-2010)Get full text
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9
γ-Tubulin in Leishmania: cell cycle-dependent changes in subcellular localization and heterogeneity of its isoforms
Published in Experimental cell research (01-05-2004)“…A panel of six anti-peptide antibodies recognizing epitopes in different regions of the γ-tubulin molecule was used for the characterization and localization…”
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