Search Results - "Libregts, Sten F"

Physical association of low density lipoprotein particles and extracellular vesicles unveiled by single particle analysis by Lozano‐Andrés, Estefanía, Enciso‐Martinez, Agustin, Gijsbers, Abril, Ridolfi, Andrea, Van Niel, Guillaume, Libregts, Sten F. W. M., Pinheiro, Cláudio, Herwijnen, Martijn J. C., Hendrix, An, Brucale, Marco, Valle, Francesco, Peters, Peter J., Otto, Cees, Arkesteijn, Ger J. A., Wauben, Marca H. M.

“…Extracellular vesicles (EVs) in blood plasma are recognized as potential biomarkers for disease. Although blood plasma is easily obtainable, analysis of EVs at…”
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Secretion of pro‐angiogenic extracellular vesicles during hypoxia is dependent on the autophagy‐related protein GABARAPL1 by Keulers, Tom G., Libregts, Sten F., Beaumont, Joel E.J., Savelkouls, Kim G., Bussink, Johan, Duimel, Hans, Dubois, Ludwig, Zonneveld, Marijke I., López‐Iglesias, Carmen, Bezstarosti, Karel, Demmers, Jeroen A., Vooijs, Marc, Wauben, Marca, Rouschop, Kasper M.A.

“…Tumour hypoxia is a hallmark of solid tumours and contributes to tumour progression, metastasis development and therapy resistance. In response to hypoxia,…”
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Tetraspanin-decorated extracellular vesicle-mimetics as a novel adaptable reference material by Lozano-Andrés, Estefanía, Libregts, Sten F., Toribio, Victor, Royo, Félix, Morales, Sara, López-Martín, Soraya, Valés-Gómez, Mar, Reyburn, Hugh T., Falcón-Pérez, Juan Manuel, Wauben, Marca H., Soto, Manuel, Yáñez-Mó, María

“…Features like small size, low refractive index and polydispersity pose challenges to the currently available detection methods for Extracellular Vesicles…”
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Improved Flow Cytometric Light Scatter Detection of Submicron‐Sized Particles by Reduction of Optical Background Signals by Arkesteijn, Ger J. A., Lozano‐Andrés, Estefanía, Libregts, Sten F. W. M., Wauben, Marca H. M.

“…Flow cytometry allows multiparameter analysis on a single‐cell basis and is currently the method of choice to rapidly assess heterogeneity of cell populations…”
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BH3-only protein Noxa contributes to apoptotic control of stress-erythropoiesis by Wensveen, Felix M., Geest, Christian R., Libregts, Sten F. W. M., Derks, Ingrid A. M., Ekert, Paul G., Labi, Verena, Villunger, Andreas, Nolte, Martijn A., Eldering, Eric

“…Apoptosis plays an essential role in the control of erythropoiesis under normal and pathological conditions. However, the contribution of individual proteins…”
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Synovial fluid pretreatment with hyaluronidase facilitates isolation of CD44+ extracellular vesicles by Boere, Janneke, van de Lest, Chris H. A., Libregts, Sten F. W. M., Arkesteijn, Ger J. A., Geerts, Willie J. C., Nolte-'t Hoen, Esther N. M., Malda, Jos, van Weeren, P. René, Wauben, Marca H. M.

“…Extracellular vesicles (EVs) in synovial fluid (SF) are gaining increased recognition as important factors in joint homeostasis, joint regeneration, and as…”
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IFNγ induces monopoiesis and inhibits neutrophil development during inflammation by de Bruin, Alexander M., Libregts, Sten F., Valkhof, Marijke, Boon, Louis, Touw, Ivo P., Nolte, Martijn A.

“…Steady-state hematopoiesis is altered on infection, but the cellular and molecular mechanisms driving these changes are largely unknown. Modulation of…”
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Acute joint inflammation induces a sharp increase in the number of synovial fluid EVs and modifies their phospholipid profile by Varela, Laura, van de Lest, Chris H.A., Boere, Janneke, Libregts, Sten F.W.M., Lozano-Andrés, Estefanía, van Weeren, P. René, Wauben, Marca H.M.

“…Inflammation is the hallmark of most joint disorders. However, the precise regulation of induction, perpetuation, and resolution of joint inflammation is not…”
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Chronic IFN-γ production in mice induces anemia by reducing erythrocyte life span and inhibiting erythropoiesis through an IRF-1/PU.1 axis by Libregts, Sten F., Gutiérrez, Laura, de Bruin, Alexander M., Wensveen, Felix M., Papadopoulos, Petros, van Ijcken, Wilfred, Özgür, Zeliha, Philipsen, Sjaak, Nolte, Martijn A.

“…Anemia of chronic disease is a complication accompanying many inflammatory diseases. The proinflammatory cytokine IFN-γ has been implicated in this form of…”
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Parallels between immune driven-hematopoiesis and T cell activation: 3 signals that relay inflammatory stress to the bone marrow by Libregts, Sten F.W.M., Nolte, Martijn A.

“…Quiescence, self-renewal, lineage commitment and differentiation of hematopoietic stem cells (HSCs) towards fully mature blood cells are a complex process that…”
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Regular Industrial Processing of Bovine Milk Impacts the Integrity and Molecular Composition of Extracellular Vesicles by Kleinjan, Marije, van Herwijnen, Martijn Jc, Libregts, Sten Fwm, van Neerven, Rj Joost, Feitsma, Anouk L, Wauben, Marca Hm

“…Bovine milk contains extracellular vesicles (EVs), which act as mediators of intercellular communication by regulating the recipients' cellular processes via…”
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MIFlowCyt-EV: a framework for standardized reporting of extracellular vesicle flow cytometry experiments by Welsh, Joshua A., Van Der Pol, Edwin, Arkesteijn, Ger J.A., Bremer, Michel, Brisson, Alain, Coumans, Frank, Dignat-George, Françoise, Duggan, Erika, Ghiran, Ionita, Giebel, Bernd, Görgens, André, Hendrix, An, Lacroix, Romaric, Lannigan, Joanne, Libregts, Sten F.W.M., Lozano-Andrés, Estefanía, Morales-Kastresana, Aizea, Robert, Stephane, De Rond, Leonie, Tertel, Tobias, Tigges, John, De Wever, Olivier, Yan, Xiaomei, Nieuwland, Rienk, Wauben, Marca H.M., Nolan, John P., Jones, Jennifer C.

“…Extracellular vesicles (EVs) are small, heterogeneous and difficult to measure. Flow cytometry (FC) is a key technology for the measurement of individual…”
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Plasma vesicle miRNAs for therapy response monitoring in Hodgkin lymphoma patients by van Eijndhoven, Monique Aj, Zijlstra, Josée M, Groenewegen, Nils J, Drees, Esther Ee, van Niele, Stuart, Baglio, S Rubina, Koppers-Lalic, Danijela, van der Voorn, Hans, Libregts, Sten Fwm, Wauben, Marca Hm, de Menezes, Renee X, van Weering, Jan Rt, Nieuwland, Rienk, Visser, Lydia, van den Berg, Anke, de Jong, Daphne, Pegtel, D Michiel

“…Cell-free circulating nucleic acids, including 22-nt microRNAs (miRNAs), represent noninvasive biomarkers for treatment response monitoring of cancer patients…”
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Characterization of EVs isolated from differently processed bovine milk by Kleinjan, Marije, Libregts, Sten F H M, Feitsma, Anouk, van Neerven, Joost, Wauben, Marca H M

“…Background: We investigated how processing of bovine milk affected the EV quantity and composition by isolating EVs from homogenized, pasteurized or…”
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GABARAPL1 is required for the secretion of pro-angiogenic extracellular vesicles during hypoxia by Keulers, Tom G H, Zonneveld, Marijke I, Libregts, Sten F H M, Wauben, Marca H M, Rouschop, Kasper M A

“…Background: Hypoxia is a hallmark of solid tumours and is associated with tumour progression and therapy resistance. In response to hypoxia, tumour cells…”
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Hypoxia-driven changes in EV composition are autophagy-dependent by Zonneveld, Marijke I, Keulers, Tom G H, Peeters, Hanneke, Libregts, Sten F H M, Wauben, Marca H M, Rouschop, Kasper M A

“…Background: Hypoxia is an important component of the tumour microenvironment (TME), correlating with increased angiogenesis, migration and treatment…”
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Bioengineered nanovesicles as extracellular vesicle-mimetics: a novel standard for extracellular vesicle analysis by Lozano-Andrés, Estefanía, Libregts, Sten F H M, Royo, Félix, López, Sara Morales, López-Martín, Soraya, Valés, Mar, Reyburn, Hugh T, Wauben, Marca H M, Falcón-Pérez, Juan M, Yáñez-Mó, María

“…Background: Adequate detection of extracellular vesicles (EVs) is difficult due to their size, low refractive index and polydispersity, as well as the lack of…”
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Chronic IFNγ Production Induces Anemia by Reducing Erythrocyte Lifespan and Inhibiting Erythropoiesis through An IRF-1/PU.1-Axis by Libregts, Sten F.W.M., Gutierrez, Laura, de Bruin, Alexander M., Wensveen, Felix M., Papadopoulos, Petros, van Ijcken, Wilfred, Ozgur, Zeliha, Philipsen, Sjaak, Nolte, Martijn A.

“…Abstract 4234 Anemia of chronic disease (ACD) is a complication accompanying many inflammatory diseases. The pro-inflammatory cytokine IFNγ has been implicated…”
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Synovial fluid pretreatment with hyaluronidase facilitates isolation of CD44^sub +^ extracellular vesicles by Boere, Janneke, van de Lest, Chris H A, Libregts, Sten F W M, Arkesteijn, Ger J A, Geerts, Willie J C, Hoen, Esther N M Nolte-'t, Malda, Jos, van Weeren, P René, Wauben, Marca H M

“…Extracellular vesicles (EVs) in synovial fluid (SF) are gaining increased recognition as important factors in joint homeostasis, joint regeneration, and as…”
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