Search Results - "Libert, F"
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A Rapid CRISPR/Cas-based Mutagenesis Assay in Zebrafish for Identification of Genes Involved in Thyroid Morphogenesis and Function
Published in Scientific reports (04-04-2018)“…The foregut endoderm gives rise to several organs including liver, pancreas, lung and thyroid with important roles in human physiology. Understanding which…”
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Analgesic effect of acetaminophen in humans: First evidence of a central serotonergic mechanism
Published in Clinical pharmacology and therapeutics (01-04-2006)“…Objectives Preclinical studies have suggested that the mechanism of the analgesic action of acetaminophen (INN, paracetamol) is linked to the serotonergic…”
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Kinetochore KMN network gene CASC5 mutated in primary microcephaly
Published in Human molecular genetics (15-12-2012)“…Several genes expressed at the centrosome or spindle pole have been reported to underlie autosomal recessive primary microcephaly (MCPH), a neurodevelopmental…”
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Global profiling of genes modified by endoplasmic reticulum stress in pancreatic beta cells reveals the early degradation of insulin mRNAs
Published in Diabetologia (01-05-2007)“…Aims/hypothesis Pancreatic beta cells respond to endoplasmic reticulum (ER) stress by activating the unfolded protein response. If the stress is prolonged, or…”
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Evidence for a differential opioidergic involvement in the analgesic effect of antidepressants: prediction for efficacy in animal models of neuropathic pain?
Published in British journal of pharmacology (01-06-2011)“…BACKGROUND AND PURPOSE Antidepressants are one of the recommended treatments for neuropathic pain. However, their analgesic action remains unpredictable, and…”
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Gene expression and the biological phenotype of papillary thyroid carcinomas
Published in Oncogene (13-12-2007)“…The purpose of this paper is to correlate the molecular phenotype of papillary thyroid carcinoma (PTC) to their biological pathology. We hybridized 26 PTC on…”
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Determination of irinotecan and SN38 in human plasma by TurboFlow™ liquid chromatography-tandem mass spectrometry
Published in Journal of pharmaceutical and biomedical analysis (25-01-2016)“…Irinotecan is a cytotoxic agent used in the treatment of metastatic colorectal cancer. Irinotecan is a prodrug when is converted in vivo to an active…”
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Development of a Bayesian estimator for the therapeutic drug monitoring of mycophenolate mofetil in children with idiopathic nephrotic syndrome
Published in Pharmacological research (01-05-2011)“…The use of mycophenolate mofetil (MMF) in children with idiopathic nephrotic syndrome (INS) is increasing. However, the clinical benefit of its monitoring has…”
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Genome-wide gene expression profiling suggests distinct radiation susceptibilities in sporadic and post-Chernobyl papillary thyroid cancers
Published in British journal of cancer (11-09-2007)“…Papillary thyroid cancers (PTCs) incidence dramatically increased in the vicinity of Chernobyl. The cancer-initiating role of radiation elsewhere is debated…”
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Hyperosmotic stress induces cell cycle arrest in retinal pigmented epithelial cells
Published in Cell death & disease (01-06-2013)“…Osmotic changes occur in many tissues and profoundly influence cell function. Herein, we investigated the effect of hyperosmotic stress on retinal pigmented…”
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Resistance to HIV-1 infection in Caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene
Published in Nature (London) (22-08-1996)“…HIV-1 and related viruses require co-receptors, in addition to CD4, to infect target cells. The chemokine receptor CCR-5 (ref.1) was recently demonstrated to…”
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The effect of phytostabilization on Zn speciation in a dredged contaminated sediment using scanning electron microscopy, X-ray fluorescence, EXAFS spectroscopy, and principal components analysis
Published in Geochimica et cosmochimica acta (01-05-2005)“…The maintenance of waterways generates large amounts of dredged sediments, which are deposited on adjacent land surfaces. These sediments are often rich in…”
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Dual-Specificity Phosphatase 3 Deletion Protects Female, but Not Male, Mice from Endotoxemia-Induced and Polymicrobial-Induced Septic Shock
Published in The Journal of immunology (1950) (01-10-2017)“…Dual-specificity phosphatase 3 (DUSP3) is a small phosphatase with poorly known physiological functions and for which only a few substrates are known. Using…”
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Hyperosmotic stress induces cell cycle arrest in retinal pigmented epithelial cells
Published in Cell death & disease (06-06-2013)Get full text
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P03-327 - What about dosing olanzapine plasma concentration in mania? Plasma threshold determination
Published in European psychiatry (2010)“…Objectives Olanzapine plasma concentration ≥ 23, 2 ng/ml have been identified as a predictor of clinical response in acutely ill patients with schizophrenia…”
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Multiple nonfunctional alleles of CCR5 are frequent in various human populations
Published in Blood (01-09-2000)“…CCR5 is the major coreceptor for macrophage-tropic strains of the human immunodeficiency virus type I (HIV-1). Homozygotes for a 32-base pair (bp) deletion in…”
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Impact of deep freezing on the stability of 25 mg/ml vancomycin ophthalmic solutions
Published in International journal of pharmaceutics (02-03-2002)“…For the treatment of certain eye infections, ophthalmic solutions ‘laced’ with 25 mg/ml vancomycin are sometimes prepared. Their physical and chemical…”
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Role of CCR5 in infection of primary macrophages and lymphocytes by macrophage-tropic strains of human immunodeficiency virus: resistance to patient-derived and prototype isolates resulting from the delta ccr5 mutation
Published in Journal of Virology (01-04-1997)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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