ProtozoaDB: dynamic visualization and exploration of protozoan genomes

ProtozoaDB (http://www.biowebdb.org/protozoadb) is being developed to initially host both genomics and post-genomics data from Plasmodium falciparum, Entamoeba histolytica, Trypanosoma brucei, T. cruzi and Leishmania major, but will hopefully host other protozoan species as more genomes are sequence...

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Bibliographic Details
Published in:	Nucleic acids research Vol. 36; no. suppl-1; pp. D547 - D552
Main Authors:	Dávila, Alberto M. R., Mendes, Pablo N., Wagner, Glauber, Tschoeke, Diogo A., Cuadrat, Rafael R. C., Liberman, Felipe, Matos, Luciana, Satake, Thiago, Ocaña, Kary A. C. S., Triana, Omar, Cruz, Sérgio M. S., Jucá, Henrique C. L., Cury, Juliano C., Silva, Fabricio N., Geronimo, Guilherme A., Ruiz, Margarita, Ruback, Eduardo, Silva, Floriano P., Probst, Christian M., Grisard, Edmundo C., Krieger, Marco A., Goldenberg, Samuel, Cavalcanti, Maria C. R., Moraes, Milton O., Campos, Maria L. M., Mattoso, Marta
Format:	Journal Article
Language:	English
Published:	England Oxford University Press 01-01-2008 Oxford Publishing Limited (England)
Subjects:	Animals Computer Graphics Databases, Genetic Entamoeba histolytica Entamoeba histolytica - genetics Genome, Protozoan Genomics Internet Leishmania major Leishmania major - genetics Plasmodium falciparum Plasmodium falciparum - genetics Protozoan Proteins - chemistry Software Trypanosoma brucei Trypanosoma brucei brucei - genetics Trypanosoma cruzi - genetics User-Computer Interface
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Summary:	ProtozoaDB (http://www.biowebdb.org/protozoadb) is being developed to initially host both genomics and post-genomics data from Plasmodium falciparum, Entamoeba histolytica, Trypanosoma brucei, T. cruzi and Leishmania major, but will hopefully host other protozoan species as more genomes are sequenced. It is based on the Genomics Unified Schema and offers a modern Web-based interface for user-friendly data visualization and exploration. This database is not intended to duplicate other similar efforts such as GeneDB, PlasmoDB, TcruziDB or even TDRtargets, but to be complementary by providing further analyses with emphasis on distant similarities (HMM-based) and phylogeny-based annotations including orthology analysis. ProtozoaDB will be progressively linked to the above-mentioned databases, focusing in performing a multi-source dynamic combination of information through advanced interoperable Web tools such as Web services. Also, to provide Web services will allow third-party software to retrieve and use data from ProtozoaDB in automated pipelines (workflows) or other interoperable Web technologies, promoting better information reuse and integration. We also expect ProtozoaDB to catalyze the development of local and regional bioinformatics capabilities (research and training), and therefore promote/enhance scientific advancement in developing countries.
Bibliography:	ark:/67375/HXZ-XS2W2P7B-F istex:B863E3F6EFAB4402451D20F5E65AE41EE0ED3363 ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 ObjectType-Article-2 ObjectType-Feature-1
ISSN:	0305-1048 1362-4962
DOI:	10.1093/nar/gkm820