Search Results - "Liberman, Deborah A."
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Cancer cell states recur across tumor types and form specific interactions with the tumor microenvironment
Published in Nature genetics (01-08-2022)“…Transcriptional heterogeneity among malignant cells of a tumor has been studied in individual cancer types and shown to be organized into cancer cell states;…”
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Microglial responses to inflammatory challenge in adult rats altered by developmental exposure to polychlorinated biphenyls in a sex-specific manner
Published in Neurotoxicology (Park Forest South) (01-09-2024)“…Polychlorinated biphenyls are ubiquitous environmental contaminants linkedc with peripheral immune and neural dysfunction. Neuroimmune signaling is critical to…”
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Sex-specific effects of developmental exposure to polychlorinated biphenyls on neuroimmune and dopaminergic endpoints in adolescent rats
Published in Neurotoxicology and teratology (01-05-2020)“…Exposure to environmental contaminants early in life can have long lasting consequences for physiological function. Polychlorinated biphenyls (PCBs) are a…”
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Cellular adaptation to cancer therapy along a resistance continuum
Published in Nature (London) (25-07-2024)“…Advancements in precision oncology over the past decades have led to new therapeutic interventions, but the efficacy of such treatments is generally limited by…”
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Abstract 1600: Dose-dependent effects of interferon-gamma treatment on pancreatic ductal adenocarcinoma cell states
Published in Cancer research (Chicago, Ill.) (15-06-2022)“…Interferon-gamma (IFNγ) is a canonical proinflammatory cytokine that has well-studied antitumor functions such as the upregulation of MHC Class I (MHC-I),…”
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