Search Results - "Liberatore, Gabriel T"

Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease by Przedborski, Serge, Liberatore, Gabriel T, Jackson-Lewis, Vernice, Vukosavic, Slobodanka, Mandir, Allen S, Vila, Miquel, McAuliffe, W. Geoffrey, Dawson, Valina L, Dawson, Ted M

“…MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) damages dopaminergic neurons as seen in Parkinson disease. Here we show that after administration of MPTP…”
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Activated Macrophages and Microglia Induce Dopaminergic Sprouting in the Injured Striatum and Express Brain-Derived Neurotrophic Factor and Glial Cell Line-Derived Neurotrophic Factor by Batchelor, Peter E, Liberatore, Gabriel T, Wong, John Y. F, Porritt, Michelle J, Frerichs, Fenneke, Donnan, Geoffrey A, Howells, David W

“…Nigrostriatal dopaminergic neurons undergo sprouting around the margins of a striatal wound. The mechanism of this periwound sprouting has been unclear. In…”
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Inducing stroke in aged, hypertensive, diabetic rats by Rewell, Sarah SJ, Fernandez, John A, Cox, Susan F, Spratt, Neil J, Hogan, Lisa, Aleksoska, Elena, van Raay, Leena, Liberatore, Gabriel T, Batchelor, Peter E, Howells, David W

“…Animal models of ischemic stroke often neglect comorbidities common in patients. This study shows the feasibility of inducing stroke by 2 h of thread occlusion…”
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Vampire bat salivary plasminogen activator (desmoteplase) inhibits tissue-type plasminogen activator-induced potentiation of excitotoxic injury by REDDROP, Courtney, MOLDRICH, Randal X, BEART, Philip M, FARSO, Mark, LIBERATORE, Gabriel T, HOWELLS, David W, PETERSEN, Karl-Uwe, SCHLEUNING, Wolf-Dieter, MEDCALF, Robert L

“…In contrast to tissue-type plasminogen activator (tPA), vampire bat (Desmodus rotundus) salivary plasminogen activator (desmoteplase [DSPA]) does not promote…”
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Vampire bat salivary plasminogen activator (desmoteplase): A unique fibrinolytic enzyme that does not promote neurodegeneration by LIBERATORE, Gabriel T, SAMSON, André, BLADIN, Christopher, SCHLEUNING, Wolf-Dieter, MEDCALF, Robert L

“…Tissue-type plasminogen activator (tPA) promotes excitotoxic and ischemic injury within the brain. These findings have implications for the use of tPA in the…”
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Expression of glial cell line-derived neurotrophic factor (GDNF) mRNA following mechanical injury to mouse striatum by LIBERATORE, G. T, WONG, J. Y. F, PORRITT, M. J, DONNAN, G. A, HOWELLS, D. W

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Does tissue plasminogen activator mediate neurogeneneration in the 1-methyl-4-phenyl-1, 2, 3, 6- tetrahydropyridine (MPTP) mouse model of Parkinson's disease? by Liberatore, Gabriel T, Mok, Swee Jin, Sidon, Kate, Howells, David W

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Imaging the ischemic penumbra with 18F-fluoromisonidazole in a rat model of ischemic stroke by SAITA, Kazuko, CHEN, Michelle, SACHINIDIS, John I, HOWELLS, David W, SPRATT, Neil J, PORRITT, Michelle J, LIBERATORE, Gabriel T, READ, Stephen J, LEVI, Christopher R, DONNAN, Geoffrey A, ACKERMANN, Uwe, TOCHON-DANGUY, Henri J

“…The ischemic penumbra is a major focus of stroke research. 18F-fluoromisonidazole (18F-FMISO), a positron emission tomography (PET) marker of hypoxic cells,…”
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Imaging the Ischemic Penumbra with 18 F-Fluoromisonidazole in a Rat Model of Ischemic Stroke by Saita, Kazuko, Chen, Michelle, Spratt, Neil J., Porritt, Michelle J., Liberatore, Gabriel T., Read, Stephen J., Levi, Christopher R., Donnan, Geoffrey A., Ackermann, Uwe, Tochon-Danguy, Henri J., Sachinidis, John I., Howells, David W.

“…Background and Purpose— The ischemic penumbra is a major focus of stroke research. 18 F-fluoromisonidazole ( 18 F-FMISO), a positron emission tomography (PET)…”
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Expression of glial cell line-derived neurotrophic factor (GDNF) mRNA following mechanical injury to mouse striatum by Liberatore, Gabriel T, Wong, John Y. F, Porritt, Michelle J, Donnan, Geoffrey A, Howells, David W

“…ALTHOUGH glial cell line-derived neurotrophic factor (GDNF) expression is low in the adult brain, its administration protects dopaminergic neurons against a…”
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Dopaminergic responses to striatal damage by Howells, David W., Liberatore, Gabriel T., Wong, John Y.F., Donnan, Geoffrey A.

“…The improvements obtained by grafting dopamine-rich tissues into the striatum of patients with Parkinson's disease are generally attributed to production and…”
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