Search Results - "Liberali, Prisca"

Organoids in image-based phenotypic chemical screens by Lukonin, Ilya, Zinner, Marietta, Liberali, Prisca

“…Image-based phenotypic screening relies on the extraction of multivariate information from cells cultured under a large variety of conditions. Technical…”
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Cell fate coordinates mechano-osmotic forces in intestinal crypt formation by Yang, Qiutan, Xue, Shi-Lei, Chan, Chii Jou, Rempfler, Markus, Vischi, Dario, Maurer-Gutierrez, Francisca, Hiiragi, Takashi, Hannezo, Edouard, Liberali, Prisca

“…Intestinal organoids derived from single cells undergo complex crypt–villus patterning and morphogenesis. However, the nature and coordination of the…”
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Exploring single cells in space and time during tissue development, homeostasis and regeneration by Mayr, Urs, Serra, Denise, Liberali, Prisca

“…Complex 3D tissues arise during development following tightly organized events in space and time. In particular, gene regulatory networks and local…”
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Self-organization and symmetry breaking in intestinal organoid development by Serra, Denise, Mayr, Urs, Boni, Andrea, Lukonin, Ilya, Rempfler, Markus, Challet Meylan, Ludivine, Stadler, Michael B., Strnad, Petr, Papasaikas, Panagiotis, Vischi, Dario, Waldt, Annick, Roma, Guglielmo, Liberali, Prisca

“…Intestinal organoids are complex three-dimensional structures that mimic the cell-type composition and tissue organization of the intestine by recapitulating…”
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Single-cell and multivariate approaches in genetic perturbation screens by Liberali, Prisca, Snijder, Berend, Pelkmans, Lucas

“…Key Points There are a number of different methods and techniques for genetic perturbation screens. The phenomenon of cell-to-cell variability in mammalian…”
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A hierarchical map of regulatory genetic interactions in membrane trafficking by Liberali, Prisca, Snijder, Berend, Pelkmans, Lucas

“…Endocytosis is critical for cellular physiology and thus is highly regulated. To identify regulatory interactions controlling the endocytic membrane system, we…”
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The Organoid Cell Atlas by Bock, Christoph, Boutros, Michael, Camp, J. Gray, Clarke, Laura, Clevers, Hans, Knoblich, Juergen A., Liberali, Prisca, Regev, Aviv, Rios, Anne C., Stegle, Oliver, Stunnenberg, Hendrik G., Teichmann, Sarah A., Treutlein, Barbara, Vries, Robert G. J.

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From single cells to tissue self‐organization by Xavier da Silveira dos Santos, Aline, Liberali, Prisca

“…Self‐organization is a process by which interacting cells organize and arrange themselves in higher order structures and patterns. To achieve this, cells must…”
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Trajectories of cell-cycle progression from fixed cell populations by Gut, Gabriele, Tadmor, Michelle D, Pe'er, Dana, Pelkmans, Lucas, Liberali, Prisca

“…Cycler constructs a trajectory of cell-cycle progression from fixed images of cells enabling the correlation of an individual cell's position in the cell cycle…”
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Multiscale light-sheet organoid imaging framework by de Medeiros, Gustavo, Ortiz, Raphael, Strnad, Petr, Boni, Andrea, Moos, Franziska, Repina, Nicole, Challet Meylan, Ludivine, Maurer, Francisca, Liberali, Prisca

“…Organoids provide an accessible in vitro system to mimic the dynamics of tissue regeneration and development. However, long-term live-imaging of organoids…”
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Engineering human knock-in organoids by Yang, Qiutan, Oost, Koen C., Liberali, Prisca

“…The lack of endogenous reporter lines is a bottleneck in the study of subcellular dynamics in human adult stem cell (ASC)-derived organoids. An approach using…”
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Single‐cell biology: what does the future hold? by Polychronidou, Maria, Hou, Jingyi, Babu, M Madan, Liberali, Prisca, Amit, Ido, Deplancke, Bart, Lahav, Galit, Itzkovitz, Shalev, Mann, Matthias, Saez‐Rodriguez, Julio, Theis, Fabian, Eils, Roland

“…Graphical Abstract In this Editorial, our Chief Editor and members of our Advisory Editorial Board discuss recent breakthroughs, current challenges, and…”
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Single‐cell analysis of population context advances RNAi screening at multiple levels by Snijder, Berend, Sacher, Raphael, Rämö, Pauli, Liberali, Prisca, Mench, Karin, Wolfrum, Nina, Burleigh, Laura, Scott, Cameron C, Verheije, Monique H, Mercer, Jason, Moese, Stefan, Heger, Thomas, Theusner, Kristina, Jurgeit, Andreas, Lamparter, David, Balistreri, Giuseppe, Schelhaas, Mario, De Haan, Cornelis A M, Marjomäki, Varpu, Hyypiä, Timo, Rottier, Peter J M, Sodeik, Beate, Marsh, Mark, Gruenberg, Jean, Amara, Ali, Greber, Urs, Helenius, Ari, Pelkmans, Lucas

“…Isogenic cells in culture show strong variability, which arises from dynamic adaptations to the microenvironment of individual cells. Here we study the…”
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Epithelial GPR35 protects from Citrobacter rodentium infection by preserving goblet cells and mucosal barrier integrity by Melhem, Hassan, Kaya, Berna, Kaymak, Tanay, Wuggenig, Philipp, Flint, Emilio, Roux, Julien, Oost, Koen C., Cavelti-Weder, Claudia, Balmer, Maria L., Walser, Jean-Claude, Morales, Rodrigo A., Riedel, Christian U., Liberali, Prisca, Villablanca, Eduardo J., Niess, Jan Hendrik

“…Goblet cells secrete mucin to create a protective mucus layer against invasive bacterial infection and are therefore essential for maintaining intestinal…”
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Systematically quantifying morphological features reveals constraints on organoid phenotypes by Beck, Lauren E, Lee, Jasmine, Coté, Christopher, Dunagin, Margaret C, Lukonin, Ilya, Salla, Nikkita, Chang, Marcello K, Hughes, Alex J, Mornin, Joseph D, Gartner, Zev J, Liberali, Prisca, Raj, Arjun

“…Organoids recapitulate complex 3D organ structures and represent a unique opportunity to probe the principles of self-organization. While we can alter an…”
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Molecular mechanism and functional role of brefeldin A-mediated ADP-ribosylation of CtBP1/BARS by Colanzi, Antonino, Grimaldi, Giovanna, Catara, Giuliana, Valente, Carmen, Cericola, Claudia, Liberali, Prisca, Ronci, Maurizio, Lalioti, Vasiliki S, Bruno, Agostino, Beccari, Andrea R, Urbani, Andrea, De Flora, Antonio, Nardini, Marco, Bolognesi, Martino, Luini, Alberto, Corda, Daniela

“…ADP-ribosylation is a posttranslational modification that modulates the functions of many target proteins. We previously showed that the fungal toxin brefeldin…”
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Primed Track, high-fidelity lineage tracing in mouse pre-implantation embryos using primed conversion of photoconvertible proteins by Welling, Maaike, Mohr, Manuel Alexander, Ponti, Aaron, Rullan Sabater, Lluc, Boni, Andrea, Kawamura, Yumiko K, Liberali, Prisca, Peters, Antoine Hfm, Pelczar, Pawel, Pantazis, Periklis

“…Accurate lineage reconstruction of mammalian pre-implantation development is essential for inferring the earliest cell fate decisions. Lineage tracing using…”
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A Raft-derived, Pak1-regulated Entry Participates in α2β1 Integrin-dependent Sorting to Caveosomes by Karjalainen, Mikko, Kakkonen, Elina, Upla, Paula, Paloranta, Heli, Kankaanpää, Pasi, Liberali, Prisca, Renkema, G. Herma, Hyypiä, Timo, Heino, Jyrki, Marjomäki, Varpu

“…We have previously shown that a human picornavirus echovirus 1 (EV1) is transported to caveosomes during 2 h together with its receptor α2β1 integrin. Here, we…”
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Electron Transfer and Singlet Oxygen Mechanisms in the Photooxygenation of Dibutyl Sulfide and Thioanisole in MeCN Sensitized by N-Methylquinolinium Tetrafluoborate and 9,10-Dicyanoanthracene. The Probable Involvement of a Thiadioxirane Intermediate in Electron Transfer Photooxygenations by Baciocchi, Enrico, Giacco, Tiziana Del, Elisei, Fausto, Gerini, Maria Francesca, Guerra, Maurizio, Lapi, Andrea, Liberali, Prisca

“…Photooxygenations of PhSMe and Bu2S sensitized by N-methylquinolinium (NMQ+) and 9,10-dicyanoanthracene (DCA) in O2-saturated MeCN have been investigated by…”
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Cell scientist to watch – Prisca Liberali

“…ABSTRACT Prisca Liberali studied chemistry at Università degli Studi di Roma ‘La Sapienza’ in Rome, Italy. She then pursued her PhD in physical chemistry,…”
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