Search Results - "Liao, Qianjin"
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1
AKT and ERK dual inhibitors: The way forward?
Published in Cancer letters (10-09-2019)“…Phosphatidylinositol 3-kinase (PI3K)/AKT pathway regulates cell growth, proliferation, survival, mobility and invasion. Mitogen-activated protein kinase…”
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2
The cancer metabolic reprogramming and immune response
Published in Molecular cancer (05-02-2021)“…The overlapping metabolic reprogramming of cancer and immune cells is a putative determinant of the antitumor immune response in cancer. Increased evidence…”
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3
Circular RNAs in Cancer: emerging functions in hallmarks, stemness, resistance and roles as potential biomarkers
Published in Molecular cancer (18-04-2019)“…Circular RNAs (circRNAs) are a class of RNA molecules with closed loops and high stability. CircRNAs are abundantly expressed in eukaryotic organisms and…”
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4
circGFRA1 and GFRA1 act as ceRNAs in triple negative breast cancer by regulating miR-34a
Published in Journal of experimental & clinical cancer research (16-10-2017)“…Accumulating evidences indicate that circular RNAs (circRNAs), a class of non-coding RNAs, play important roles in tumorigenesis. However, the function of…”
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5
The role of microenvironment in tumor angiogenesis
Published in Journal of experimental & clinical cancer research (30-09-2020)“…Abstract Tumor angiogenesis is necessary for the continued survival and development of tumor cells, and plays an important role in their growth, invasion, and…”
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Mechanisms of vasculogenic mimicry in hypoxic tumor microenvironments
Published in Molecular cancer (04-01-2021)“…Vasculogenic mimicry (VM) is a recently discovered angiogenetic process found in many malignant tumors, and is different from the traditional angiogenetic…”
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7
circSETD3 regulates MAPRE1 through miR-615-5p and miR-1538 sponges to promote migration and invasion in nasopharyngeal carcinoma
Published in Oncogene (14-01-2021)“…Circular RNAs (circRNAs) play an essential role in tumorigenesis and development. However, they have rarely been investigated in nasopharyngeal carcinoma…”
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8
Predictive biomarkers and mechanisms underlying resistance to PD1/PD-L1 blockade cancer immunotherapy
Published in Molecular cancer (30-01-2020)“…Immune checkpoint blockade targeting PD-1/PD-L1 has promising therapeutic efficacy in a variety of tumors, but resistance during treatment is a major issue. In…”
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9
Metabolic reprogramming and epigenetic modifications in cancer: from the impacts and mechanisms to the treatment potential
Published in Experimental & molecular medicine (01-07-2023)“…Metabolic reprogramming and epigenetic modifications are hallmarks of cancer cells. In cancer cells, metabolic pathway activity varies during tumorigenesis and…”
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10
Chronic Stress Promotes Cancer Development
Published in Frontiers in oncology (19-08-2020)“…Stress is an inevitable part of life. Chronic stress on account of reasons like adversity, depression, anxiety, or loneliness/social isolation can endanger…”
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11
Single-cell RNA sequencing in cancer research
Published in Journal of experimental & clinical cancer research (01-03-2021)“…Single-cell RNA sequencing (scRNA-seq), a technology that analyzes transcriptomes of complex tissues at single-cell levels, can identify differential gene…”
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12
TRPM7 promotes the epithelial-mesenchymal transition in ovarian cancer through the calcium-related PI3K / AKT oncogenic signaling
Published in Journal of experimental & clinical cancer research (28-02-2019)“…The epithelial-mesenchymal transition (EMT) is crucial for metastasis and positively regulated by calcium-related signaling. The melastatin-related transient…”
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13
CD38: An important regulator of T cell function
Published in Biomedicine & pharmacotherapy (01-09-2022)“…Cluster of differentiation 38 (CD38) is a multifunctional extracellular enzyme on the cell surface with NADase and cyclase activities. CD38 is not only…”
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14
Effects of altered glycolysis levels on CD8+ T cell activation and function
Published in Cell death & disease (08-07-2023)“…CD8 + T cells are an important component of the body’s adaptive immune response. During viral or intracellular bacterial infections, CD8 + T cells are rapidly…”
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15
Cancer stem cells in progression of colorectal cancer
Published in Oncotarget (07-09-2018)“…Colorectal cancer is one of the most common cancers worldwide with high mortality. Distant metastasis and relapse are major causes of patient death. Cancer…”
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16
Exosomal miRNAs in tumor microenvironment
Published in Journal of experimental & clinical cancer research (16-04-2020)“…Tumor microenvironment (TME) is the internal environment in which tumor cells survive, consisting of tumor cells, fibroblasts, endothelial cells, and immune…”
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17
‘Reverse Warburg effect’ of cancer‑associated fibroblasts (Review)
Published in International journal of oncology (01-06-2022)“…Metabolic reprogramming is one of the main characteristics of malignant tumors. The metabolic reprogramming of tumors is not only related to the…”
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18
Overview and countermeasures of cancer burden in China
Published in Science China. Life sciences (01-11-2023)“…Cancer is one of the leading causes of human death worldwide. Treatment of cancer exhausts significant medical resources, and the morbidity and mortality…”
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Circular RNA circRNF13 inhibits proliferation and metastasis of nasopharyngeal carcinoma via SUMO2
Published in Molecular cancer (31-08-2021)“…Circular RNAs (circRNAs) are widely expressed in human cells and are closely associated with cancer development. However, they have rarely been investigated in…”
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20
The POU2F1-ALDOA axis promotes the proliferation and chemoresistance of colon cancer cells by enhancing glycolysis and the pentose phosphate pathway activity
Published in Oncogene (11-02-2022)“…Cancer metabolic reprogramming enhances its malignant behaviors and drug resistance, which is regulated by POU domain transcription factors. This study…”
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