Search Results - "Liao, Leen"
-
1
Inflammation promotes resistance to immune checkpoint inhibitors in high microsatellite instability colorectal cancer
Published in Nature communications (28-11-2022)“…Inflammation is a common medical complication in colorectal cancer (CRC) patients, which plays significant roles in tumor progression and immunosuppression…”
Get full text
Journal Article -
2
Application of iron/barium ferrite/carbon-coated iron nanocrystal composites in transcatheter arterial chemoembolization of hepatocellular carcinoma
Published in Journal of colloid and interface science (01-11-2021)“…Fe/BaFe12O19/CCINs nanocomposites for the treatment of liver cancer with the triple effects of chemosensitization, embolization, and thermal ablation under…”
Get full text
Journal Article -
3
The effects of oxaliplatin-based adjuvant chemotherapy in high-risk stage II colon cancer with mismatch repair-deficient: a retrospective study
Published in BMC cancer (02-02-2024)“…For high-risk stageIImismatch repair deficient (dMMR) colon cancers, the benefit of adjuvant chemotherapy remains debatable. The principal aim of this study…”
Get full text
Journal Article -
4
Neoadjuvant chemotherapy weakens the prognostic value of the pathological tumor burden score for colorectal cancer liver metastases
Published in BMC surgery (09-09-2023)“…Abstract Background The pathological tumor burden score (TBS) has been proven to be a better risk stratification tool for liver metastasis of colorectal cancer…”
Get full text
Journal Article -
5
Dickkopf 1 impairs the tumor response to PD-1 blockade by inactivating CD8+ T cells in deficient mismatch repair colorectal cancer
Published in Journal for immunotherapy of cancer (01-03-2021)“…BackgroundDickkopf 1 (DKK1) is associated with tumor progression. However, whether DKK1 influences the tumor response to programmed cell death protein 1 (PD-1)…”
Get full text
Journal Article -
6
A novel screening method of DNA methylation biomarkers helps to improve the detection of colorectal cancer and precancerous lesions
Published in Cancer medicine (Malden, MA) (01-11-2023)“…Abstract Background Colorectal cancer (CRC) is one of the most common malignancies, and early detection plays a crucial role in enhancing curative outcomes…”
Get full text
Journal Article -
7
A novel circumferential continuous reinforcing suture for anastomosis after laparoscopic resection for rectal cancer and sigmoid cancer: a retrospective case-controlled study
Published in Langenbeck's archives of surgery (12-10-2024)“…Introduction This study aimed to investigate the effectiveness of a novel method for anastomosis reinforcement to minimize the occurrence of anastomotic…”
Get full text
Journal Article -
8
Safety and effectiveness of subtotal pelvic peritonectomy for patients with colorectal cancer with limited peritoneal metastasis in pelvic cavity
Published in Journal of clinical oncology (01-06-2023)“…e15587 Background: Cytoreductive surgery with extensive visceral resection and peritonectomy has shown long-term survival benefits for colorectal cancer (CRC)…”
Get full text
Journal Article -
9
B2M and JAK1/2–mutated MSI-H Colorectal Carcinomas Can Benefit From Anti-PD-1 Therapy
Published in Journal of immunotherapy (1997) (01-05-2022)“…β2-microglobulin (B2M) and Janus kinases 1 and 2 (JAK1/2) mutations have been suggested as genetic mechanisms of immune evasion for anti–programmed cell death…”
Get full text
Journal Article -
10
Efficacy of PD-1 inhibitors for colorectal cancer and polyps in patients with Lynch syndrome
Published in Journal of clinical oncology (01-06-2023)“…e15521 Background: Programmed death-1 (PD-1) inhibitor is effective for colorectal cancer (CRC) with deficient mismatch repair (dMMR) or high microsatellite…”
Get full text
Journal Article -
11
MCT4 is an independent prognostic factor and affects immune cell infiltration in patients with colorectal liver oligometastases
Published in Clinical & translational oncology (13-09-2024)“…Monocarboxylate transporter 4 (MCT4) is a novel biomarker related to the level of immune cell infiltration, but its impact on tumor immune microenvironment…”
Get full text
Journal Article -
12
B2M and JAK1/2–mutated MSI-H Colorectal Carcinomas Can Benefit From Anti-PD-1 Therapy
Published in Journal of immunotherapy (1997) (28-03-2022)“…β2-microglobulin (B2M) and Janus kinases 1 and 2 (JAK1/2) mutations have been suggested as genetic mechanisms of immune evasion for anti–programmed cell death…”
Get full text
Journal Article -
13
DNA ploidy and stroma predicted the risk of recurrence in low-risk stage III colorectal cancer
Published in Clinical & translational oncology (01-01-2023)“…Background For clinically low-risk stage III colorectal cancer, the decision on cycles of adjuvant chemotherapy after surgery is disputed. The present study…”
Get full text
Journal Article -
14
Apatinib versus sorafenib in patients with advanced hepatocellular carcinoma: a preliminary study
Published in Annals of translational medicine (01-08-2020)“…Apatinib, a selective inhibitor of vascular endothelial growth factor receptor 2 (VEGFR 2), has exhibited modest antitumor efficacy in hepatocellular carcinoma…”
Get full text
Journal Article