Search Results - "Liao, Guojian"
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1
Patterns of IgG and IgM antibody response in COVID-19 patients
Published in Emerging microbes & infections (01-01-2020)Get full text
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Recent Advances on Octahedral Polypyridyl Ruthenium(II) Complexes as Antimicrobial Agents
Published in Polymers (10-06-2018)“…Recent developments of therapeutic agents based on transition metals have attracted a great deal of attention. Metal drugs have advantages over other small…”
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Unexpected extensive lysine acetylation in the trump-card antibiotic producer Streptomyces roseosporus revealed by proteome-wide profiling
Published in Journal of proteomics (25-06-2014)“…Lysine acetylation is emerging as a ubiquitous and conserved posttranslational modification in living cells. While the role of lysine acetylation in regulating…”
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Proteome-wide lysine acetylation profiling of the human pathogen Mycobacterium tuberculosis
Published in The international journal of biochemistry & cell biology (01-02-2015)“…Nɛ-Acetylation of lysine residues represents a pivotal post-translational modification used by both eukaryotes and prokaryotes to modulate diverse biological…”
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Cryptococcus neoformans, a global threat to human health
Published in Infectious diseases of poverty (17-03-2023)“…Emerging fungal pathogens pose important threats to global public health. The World Health Organization has responded to the rising threat of traditionally…”
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Genetic basis for coordination of meiosis and sexual structure maturation in Cryptococcus neoformans
Published in eLife (03-10-2018)“…In the human fungal pathogen , sex can benefit its pathogenicity through production of meiospores, which are believed to offer both physical and…”
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Interplay between acetylation and ubiquitination of imitation switch chromatin remodeler Isw1 confers multidrug resistance in Cryptococcus neoformans
Published in eLife (22-01-2024)“…poses a threat to human health, but anticryptococcal therapy is hampered by the emergence of drug resistance, whose underlying mechanisms remain poorly…”
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Responses of root growth and antioxidative systems of paddy rice exposed to antimony and selenium
Published in Environmental and experimental botany (01-02-2016)“…•Se and Sb mutually showed antagonistic effects on their uptake.•Sb and Se showed opposite effects on shoot and root biomass upon exposing to Se.•Se could…”
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Regulatory basis for reproductive flexibility in a meningitis-causing fungal pathogen
Published in Nature communications (24-12-2022)“…Pathogenic fungi of the genus Cryptococcus can undergo two sexual cycles, involving either bisexual diploidization (after fusion of haploid cells of different…”
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Transposon-based screen identifies a XRE family regulator crucial for candicidin biosynthesis in Streptomyces albus J1074
Published in Science China. Life sciences (01-09-2020)Get full text
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Lipid Flippase Subunit Cdc50 Mediates Drug Resistance and Virulence in Cryptococcus neoformans
Published in mBio (10-05-2016)“…Cryptococcus neoformans is a human fungal pathogen and a major cause of fungal meningitis in immunocompromised individuals. Treatment options for…”
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Candida haemulonii species complex: emerging fungal pathogens of the Metschnikowiaceae clade
Published in Zoonoses (Burlington, Mass.) (03-01-2023)“…species represent the most common fungal pathogens of humans, causing not only superficial infections but also life-threatening invasive infections, especially…”
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13
Transcriptional analysis of the effect of exogenous decanoic acid stress on Streptomyces roseosporus
Published in Microbial cell factories (21-02-2013)“…Daptomycin is an important antibiotic against infections caused by drug-resistant pathogens. Its production critically depends on the addition of decanoic acid…”
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14
Noncovalent Complexation of Amphotericin B with Poly(β-Amino Ester) Derivates for Treatment of C. Neoformans Infection
Published in Polymers (05-02-2019)“…Our goal was to improve treatment outcomes for infection by designing nanocarriers that enhance drug-encapsulating capacity and stability. Thus, a noncovalent…”
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15
Regulation mechanisms underlying the biosynthesis of daptomycin and related lipopeptides
Published in Journal of cellular biochemistry (01-03-2012)“…Daptomycin is a lipopeptide antibiotics used to treat Gram‐positive pathogens infections, including drug‐resistant strains. In‐depth exploration of its…”
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16
The Discovery of an Iridium(III) Dimer Complex as a Potent Antibacterial Agent against Non-Replicating Mycobacterium smegmatis
Published in Polymers (09-03-2018)“…Novel agents are urgently needed to rapidly kill drug-resistant . Noble metal complexes, particularly polypyridyl iridium complexes serving as therapeutic…”
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A Velvet Transcription Factor Specifically Activates Mating through a Novel Mating-Responsive Protein in the Human Fungal Pathogen Cryptococcus deneoformans
Published in Microbiology spectrum (29-06-2022)“…Sexual reproduction facilitates infection by the production of both a lineage advantage and infectious sexual spores in the ubiquitous human fungal pathogen…”
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Cisplatin protects mice from challenge of Cryptococcus neoformans by targeting the Prp8 intein
Published in Emerging microbes & infections (01-01-2019)“…The Prp8 intein is one of the most widespread eukaryotic inteins, present in important pathogenic fungi, including Cryptococcus and Aspergillus species…”
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Octahedral ruthenium (II) polypyridyl complexes as antimicrobial agents against mycobacterium
Published in PeerJ (San Francisco, CA) (27-04-2017)“…Tuberculosis is one of the world's deadliest infectious disease with 1.5 millions deaths annually. It is imperative to discover novel compounds with potent…”
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Cloning, reassembling and integration of the entire nikkomycin biosynthetic gene cluster into Streptomyces ansochromogenes lead to an improved nikkomycin production
Published in Microbial cell factories (23-01-2010)“…Nikkomycins are a group of peptidyl nucleoside antibiotics produced by Streptomyces ansochromogenes. They are competitive inhibitors of chitin synthase and…”
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