Search Results - "Liao, Gaoming"

CancerSEA: a cancer single-cell state atlas by Yuan, Huating, Yan, Min, Zhang, Guanxiong, Liu, Wei, Deng, Chunyu, Liao, Gaoming, Xu, Liwen, Luo, Tao, Yan, Haoteng, Long, Zhilin, Shi, Aiai, Zhao, Tingting, Xiao, Yun, Li, Xia

“…Abstract High functional heterogeneity of cancer cells poses a major challenge for cancer research. Single-cell sequencing technology provides an unprecedented…”
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CellMarker: a manually curated resource of cell markers in human and mouse by Zhang, Xinxin, Lan, Yujia, Xu, Jinyuan, Quan, Fei, Zhao, Erjie, Deng, Chunyu, Luo, Tao, Xu, Liwen, Liao, Gaoming, Yan, Min, Ping, Yanyan, Li, Feng, Shi, Aiai, Bai, Jing, Zhao, Tingting, Li, Xia, Xiao, Yun

“…Abstract One of the most fundamental questions in biology is what types of cells form different tissues and organs in a functionally coordinated fashion…”
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DiseaseEnhancer: a resource of human disease-associated enhancer catalog by Zhang, Guanxiong, Shi, Jian, Zhu, Shiwei, Lan, Yujia, Xu, Liwen, Yuan, Huating, Liao, Gaoming, Liu, Xiaoqin, Zhang, Yunpeng, Xiao, Yun, Li, Xia

“…Abstract Large-scale sequencing studies discovered substantial genetic variants occurring in enhancers which regulate genes via long range chromatin…”
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Single-Cell Transcriptomic Analysis Reveals a Tumor-Reactive T Cell Signature Associated With Clinical Outcome and Immunotherapy Response In Melanoma by Yan, Min, Hu, Jing, Ping, Yanyan, Xu, Liwen, Liao, Gaoming, Jiang, Zedong, Pang, Bo, Sun, Shangqin, Zhang, Yunpeng, Xiao, Yun, Li, Xia

“…The infiltration of tumor-reactive T cells in the tumor site is associated with better survival and immunotherapy response. However, tumor-reactive T cells…”
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Combined homologous recombination repair deficiency and immune activation analysis for predicting intensified responses of anthracycline, cyclophosphamide and taxane chemotherapy in triple-negative breast cancer by Liao, Gaoming, Jiang, Zedong, Yang, Yiran, Zhang, Cong, Jiang, Meiting, Zhu, Jiali, Xu, Liwen, Xie, Aimin, Yan, Min, Zhang, Yunpeng, Xiao, Yun, Li, Xia

“…Abstract Background Triple-negative breast cancer (TNBC) is a clinically aggressive disease with abundant variants that cause homologous recombination repair…”
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Single-Cell Transcriptomic Analysis Reveals the Crosstalk Propensity Between the Tumor Intermediate State and the CD8+ T Exhausted State to be Associated with Clinical Benefits in Melanoma by Zhu, Jiali, Yan, Min, Yan, Haoteng, Xu, Liwen, Jiang, Zedong, Liao, Gaoming, Zhou, Yao, Liu, Wei, Liang, Xin, Li, Xia, Xiao, Yun, Zhang, Yunpeng

“…Heterogeneous crosstalk between tumor cells and CD8+ T cells leads to substantial variation in clinical benefits from immunotherapy in melanoma. Due to spatial…”
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Dynamic regulatory networks of T cell trajectory dissect transcriptional control of T cell state transition by Yan, Min, Hu, Jing, Yuan, Huating, Xu, Liwen, Liao, Gaoming, Jiang, Zedong, Zhu, Jiali, Pang, Bo, Ping, Yanyan, Zhang, Yunpeng, Xiao, Yun, Li, Xia

“…T cells exhibit heterogeneous functional states, which correlate with responsiveness to immune checkpoint blockade and prognosis of tumor patients. However,…”
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Identifying Cancer Driver lncRNAs Bridged by Functional Effectors through Integrating Multi-omics Data in Human Cancers by Zhang, Yong, Liao, Gaoming, Bai, Jing, Zhang, Xinxin, Xu, Liwen, Deng, Chunyu, Yan, Min, Xie, Aimin, Luo, Tao, Long, Zhilin, Xiao, Yun, Li, Xia

“…The accumulation of somatic driver mutations in the human genome enables cells to gradually acquire a growth advantage and contributes to tumor development…”
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A pan‐cancer atlas of cancer hallmark‐associated candidate driver lncRNAs by Deng, Yulan, Luo, Shangyi, Zhang, Xinxin, Zou, Chaoxia, Yuan, Huating, Liao, Gaoming, Xu, Liwen, Deng, Chunyu, Lan, Yujia, Zhao, Tingting, Gao, Xu, Xiao, Yun, Li, Xia

“…Substantial cancer genome sequencing efforts have discovered many important driver genes contributing to tumorigenesis. However, very little is known about the…”
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Applicability of Anticancer Drugs for the Triple-Negative Breast Cancer Based on Homologous Recombination Repair Deficiency by Liao, Gaoming, Yang, Yiran, Xie, Aimin, Jiang, Zedong, Liao, Jianlong, Yan, Min, Zhou, Yao, Zhu, Jiali, Hu, Jing, Zhang, Yunpeng, Xiao, Yun, Li, Xia

“…Triple-negative breast cancer (TNBC) is a highly aggressive disease with historically poor outcomes, primarily due to the lack of effective targeted therapies…”
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Analysis of Mutations and Dysregulated Pathways Unravels Carcinogenic Effect and Clinical Actionability of Mutational Processes by Jiang, Zedong, Liao, Gaoming, Yang, Yiran, Lan, Yujia, Xu, Liwen, Yan, Min, Zhou, Yao, Zhu, Jiali, Liu, Wei, Bai, Jing, Xiao, Yun, Li, Xia

“…Somatic mutations accumulate over time in cancer cells as a consequence of mutational processes. However, the role of mutational processes in carcinogenesis…”
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Prioritizing Gene Cascading Paths to Model Colorectal Cancer Through Engineered Organoids by Ping, Yanyan, Xu, Chaohan, Xu, Liwen, Liao, Gaoming, Zhou, Yao, Deng, Chunyu, Lan, Yujia, Yu, Fulong, Shi, Jian, Wang, Li, Xiao, Yun, Li, Xia

“…Engineered organoids by sequential introduction of key mutations could help modeling the dynamic cancer progression. However, it remains difficult to determine…”
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TIP: A Web Server for Resolving Tumor Immunophenotype Profiling by Xu, Liwen, Deng, Chunyu, Pang, Bo, Zhang, Xinxin, Liu, Wei, Liao, Gaoming, Yuan, Huating, Cheng, Peng, Li, Feng, Long, Zhilin, Yan, Min, Zhao, Tingting, Xiao, Yun, Li, Xia

“…: Systematically tracking the tumor immunophenotype is required to understand the mechanisms of cancer immunity and improve clinical benefit of cancer…”
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Characteristics and mechanisms of controlled-release KMnO4 for groundwater remediation: Experimental and modeling investigations by Ma, Yao, Feng, Yuan, Feng, Yulin, Liao, Gaoming, Sun, Yue, Ma, Jie

“…Controlled release materials (CRMs) are emerging oxidant delivery techniques for in-situ chemical oxidation (ISCO) for groundwater remediation. Successful…”
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The Heterogeneous Cellular States of Glioblastoma Stem Cells Revealed by Single Cell Analysis by Yan, Haoteng, Zhu, Jiali, Ping, Yanyan, Yan, Min, Liao, Gaoming, Yuan, Huating, Zhou, Yao, Xiang, Fengyu, Pang, Bo, Xu, Jinyuan, Pang, Lin

“…Glioblastoma stem cells (GSCs) contributed to the progression, treatment resistance, and relapse of glioblastoma (GBM). However, current researches on GSCs…”
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Revealing the contribution of somatic gene mutations to shaping tumor immune microenvironment by Xu, Liwen, Zhu, Shiwei, Lan, Yujia, Yan, Min, Jiang, Zedong, Zhu, Jiali, Liao, Gaoming, Ping, Yanyan, Xu, Jinyuan, Pang, Bo, Zhang, Yunpeng, Xiao, Yun, Li, Xia

“…Abstract Interaction between tumor cells and immune cells determined highly heterogeneous microenvironments across patients, leading to substantial variation…”
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Discovering Rare Genes Contributing to Cancer Stemness and Invasive Potential by GBM Single-Cell Transcriptional Analysis by Pang, Lin, Hu, Jing, Li, Feng, Yuan, Huating, Yan, Min, Liao, Gaoming, Xu, Liwen, Pang, Bo, Ping, Yanyan, Xiao, Yun, Li, Xia

“…Single-cell RNA sequencing presents the sophisticated delineation of cell transcriptomes in many cancer types and highlights the tumor heterogeneity at higher…”
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Capturing functional long non-coding RNAs through integrating large-scale causal relations from gene perturbation experiments by Xu, Jinyuan, Shi, Aiai, Long, Zhilin, Xu, Liwen, Liao, Gaoming, Deng, Chunyu, Yan, Min, Xie, Aiming, Luo, Tao, Huang, Jian, Xiao, Yun, Li, Xia

“…Characterizing functions of long noncoding RNAs (lncRNAs) remains a major challenge, mostly due to the lack of lncRNA-involved regulatory relationships. A wide…”
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Characteristics and mechanisms of controlled-release KMnO 4 for groundwater remediation: Experimental and modeling investigations by Ma, Yao, Feng, Yuan, Feng, Yulin, Liao, Gaoming, Sun, Yue, Ma, Jie

“…Controlled release materials (CRMs) are emerging oxidant delivery techniques for in-situ chemical oxidation (ISCO) for groundwater remediation. Successful…”
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A pan‐cancer atlas of cancer hallmark‐associated candidate driver lnc RNA s by Deng, Yulan, Luo, Shangyi, Zhang, Xinxin, Zou, Chaoxia, Yuan, Huating, Liao, Gaoming, Xu, Liwen, Deng, Chunyu, Lan, Yujia, Zhao, Tingting, Gao, Xu, Xiao, Yun, Li, Xia

“…Substantial cancer genome sequencing efforts have discovered many important driver genes contributing to tumorigenesis. However, very little is known about the…”
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