Search Results - "Lianghong Yin"
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1
The cytokine storm and COVID‐19
Published in Journal of medical virology (01-01-2021)“…Coronavirus disease 2019 (COVID‐19), which began in Wuhan, China, in December 2019, has caused a large global pandemic and poses a serious threat to public…”
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2
Polyamine Function in Plants: Metabolism, Regulation on Development, and Roles in Abiotic Stress Responses
Published in Frontiers in plant science (10-01-2019)“…Polyamines (PAs) are low molecular weight aliphatic nitrogenous bases containing two or more amino groups. They are produced by organisms during metabolism and…”
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3
Why should we measure free 25(OH) vitamin D?
Published in The Journal of steroid biochemistry and molecular biology (01-06-2018)“…•Free 25(OH)D is superior over total 25(OH)D in liver and kidney pathologies, and in pregnancy.•In other health conditions the literature does not clear…”
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4
Metabolic Engineering of Shikimic Acid Biosynthesis Pathway for the Production of Shikimic Acid and Its Branched Products in Microorganisms: Advances and Prospects
Published in Molecules (Basel, Switzerland) (26-07-2022)“…The shikimate pathway is a necessary pathway for the synthesis of aromatic compounds. The intermediate products of the shikimate pathway and its branching…”
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5
Dynamic and Static Regulation of Nicotinamide Adenine Dinucleotide Phosphate: Strategies, Challenges, and Future Directions in Metabolic Engineering
Published in Molecules (Basel, Switzerland) (01-08-2024)“…Reduced nicotinamide adenine dinucleotide phosphate (NADPH) is a crucial cofactor in metabolic networks. The efficient regeneration of NADPH is one of the…”
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6
Small RNA-big impact: exosomal miRNAs in mitochondrial dysfunction in various diseases
Published in RNA biology (2024)“…Mitochondria are multitasking organelles involved in maintaining the cell homoeostasis. Beyond its well-established role in cellular bioenergetics,…”
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Recent Advances in Metabolic Engineering for the Biosynthesis of Phosphoenol Pyruvate-Oxaloacetate-Pyruvate-Derived Amino Acids
Published in Molecules (Basel, Switzerland) (18-06-2024)“…The phosphoenol pyruvate-oxaloacetate-pyruvate-derived amino acids (POP-AAs) comprise native intermediates in cellular metabolism, within which the phosphoenol…”
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8
Microbiome and Metabolome Analyses Reveal the Disruption of Lipid Metabolism in Systemic Lupus Erythematosus
Published in Frontiers in immunology (31-07-2020)“…Systemic lupus erythematosus (SLE) is a systemic autoimmune disease that affects thousands of people worldwide. Recently, alterations in metabolism and gut…”
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9
Constructing an Efficient Bacillus subtilis Spore Display by Using Cohesin-Dockerin Interactions
Published in Molecules (Basel, Switzerland) (23-02-2021)“…spore display has become a field of increasing interest in the past two decades. To improve the efficiency of spore display, its directed modification was…”
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10
AI-Assisted Rational Design and Activity Prediction of Biological Elements for Optimizing Transcription-Factor-Based Biosensors
Published in Molecules (Basel, Switzerland) (01-08-2024)“…The rational design, activity prediction, and adaptive application of biological elements (bio-elements) are crucial research fields in synthetic biology…”
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11
Metabolic Engineering of Microorganisms to Produce Pyruvate and Derived Compounds
Published in Molecules (Basel, Switzerland) (01-02-2023)“…Pyruvate is a hub of various endogenous metabolic pathways, including glycolysis, TCA cycle, amino acid, and fatty acid biosynthesis. It has also been used as…”
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12
Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) co-produced with L-isoleucine in Corynebacterium glutamicum WM001
Published in Microbial cell factories (15-06-2018)“…Co-production of polyhydroxyalkanoate (PHA) and amino acids makes bacteria effective microbial cell factories by secreting amino acids outside while…”
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13
Analysis of Gene Expression and TCR/B Cell Receptor Profiling of Immune Cells in Primary Sjögren's Syndrome by Single-Cell Sequencing
Published in The Journal of immunology (1950) (15-07-2022)“…Primary Sjögren's syndrome (pSS) is a chronic autoimmune disease that is estimated to affect 35 million people worldwide and is characterized by lymphocytic…”
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14
Proteomic analysis of laser captured tubular tissues reveals complement activation and mitochondrial dysfunction in autoimmune related kidney diseases
Published in Scientific reports (20-08-2024)“…Autoimmune related kidney diseases (ARKDs), including minimal change nephropathy (MCN), membranous nephropathy (MN), IgA nephropathy (IgAN), and lupus…”
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15
The SGLT2 Inhibitor Empagliflozin Might Be a New Approach for the Prevention of Acute Kidney Injury
Published in Kidney & blood pressure research (01-05-2019)“…Three randomized control trials (Canagliflozin Cardiovascular Assessment Study, Empagliflozin Cardiovascular Outcome Event Trial in Type 2 Diabetes Mellitus…”
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16
Application of Biomass-Based Triboelectrification for Particulate Matter Removal
Published in Polymers (18-10-2024)“…Electrostatic fields are crucial for achieving the highly efficient filtration of airborne pollutants. However, the dissipation of static charges over time,…”
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17
Integrated analysis of competing endogenous RNA networks in peripheral blood mononuclear cells of systemic lupus erythematosus
Published in Journal of translational medicine (21-08-2021)“…Abstract Background Systemic lupus erythematosus (SLE) is an autoimmune disease with a complicated pathogenesis, and its aetiology has not been clearly…”
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18
Multi-omics analyses of human colorectal cancer revealed three mitochondrial genes potentially associated with poor outcomes of patients
Published in Journal of translational medicine (26-06-2021)“…Abstract Background The identification of novel functional biomarkers is essential for recognizing high-risk patients, predicting recurrence, and searching for…”
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SGLT2 inhibitors improve kidney function and morphology by regulating renal metabolic reprogramming in mice with diabetic kidney disease
Published in Journal of translational medicine (14-09-2022)“…Abstract Diabetic kidney disease (DKD) is the leading cause of end-stage renal disease (ESRD) worldwide. SGLT2 inhibitors are clinically effective in halting…”
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Combined proteomics and single cell RNA-sequencing analysis to identify biomarkers of disease diagnosis and disease exacerbation for systemic lupus erythematosus
Published in Frontiers in immunology (29-11-2022)“…Systemic lupus erythematosus (SLE) is a chronic autoimmune disease for which there is no cure. Effective diagnosis and precise assessment of disease…”
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