Search Results - "Liang‐In Lin"

Zebrafish as a disease model for studying human hepatocellular carcinoma by Lu, Jeng-Wei, Ho, Yi-Jung, Yang, Yi-Ju, Liao, Heng-An, Ciou, Shih-Ci, Lin, Liang-In, Ou, Da-Liang

“…Liver cancer is one of the world’s most common cancers and the second leading cause of cancer deaths. Hepatocellular carcinoma(HCC), a primary hepatic cancer,…”
Get full text

Suramin Inhibits Chikungunya Virus Entry and Transmission by Ho, Yi-Jung, Wang, Yu-Ming, Lu, Jeng-wei, Wu, Tzong-Yuan, Lin, Liang-In, Kuo, Szu-Cheng, Lin, Chang-Chi

“…The mosquito-borne Chikungunya virus (CHIKV) is a profound global threat due to its high rate of contagion and the lack of vaccine or effective treatment…”
Get full text

DNMT3A mutations in acute myeloid leukemia: stability during disease evolution and clinical implications by Hou, Hsin-An, Kuo, Yuan-Yeh, Liu, Chieh-Yu, Chou, Wen-Chien, Lee, Ming Cheng, Chen, Chien-Yuan, Lin, Liang-In, Tseng, Mei-Hsuan, Huang, Chi-Fei, Chiang, Ying-Chieh, Lee, Fen-Yu, Liu, Ming-Chih, Liu, Chia-Wen, Tang, Jih-Luh, Yao, Ming, Huang, Shang-Yi, Ko, Bor-Sheng, Hsu, Szu-Chun, Wu, Shang-Ju, Tsay, Woei, Chen, Yao-Chang, Tien, Hwei-Fang

“…DNMT3A mutations are associated with poor prognosis in acute myeloid leukemia (AML), but the stability of this mutation during the clinical course remains…”
Get full text

Repurposing cabozantinib with therapeutic potential in KIT-driven t(8;21) acute myeloid leukaemias by Su, Kuan-Wei, Ou, Da-Liang, Fu, Yu-Hsuan, Tien, Hwei-Fang, Hou, Hsin-An, Lin, Liang-In

“…Cabozantinib is an orally available, multi-target tyrosine kinase inhibitor approved for the treatment of several solid tumours and known to inhibit KIT…”
Get full text

Validation of the prognostic significance of the 2022 European LeukemiaNet risk stratification system in intensive chemotherapy treated aged 18 to 65 years patients with de novo acute myeloid leukemia by Lo, Min‐Yen, Tsai, Xavier Cheng‐Hong, Lin, Chien‐Chin, Tien, Feng‐Ming, Kuo, Yuan‐Yeh, Lee, Wan‐Hsuan, Peng, Yen‐Ling, Liu, Ming‐Chih, Tseng, Mei‐Hsuan, Hsu, Cheng‐An, Chen, Jui‐Che, Lin, Liang‐In, Sun, Hsun‐I, Chuang, Yi‐Kuang, Ko, Bor‐Sheng, Tang, Jih‐Luh, Yao, Ming, Chou, Wen‐Chien, Hou, Hsin‐An, Tien, Hwei‐Fang

“…The European LeukemiaNet (ELN) recently proposed a revised recommendation for the diagnosis and management of acute myeloid leukemia (AML) in adults,…”
Get full text

Distinct molecular genetics of chronic lymphocytic leukemia in Taiwan: clinical and pathogenetic implications by Wu, Shang-Ju, Lin, Chien-Ting, Agathangelidis, Andreas, Lin, Liang-In, Kuo, Yuan-Yeh, Tien, Hwei-Fang, Ghia, Paolo

“…Differences in chronic lymphocytic leukemia between the Asian and the Western population are widely known. To further clarify these ethnic differences, we…”
Get full text

Ovarian and endometrial endometrioid adenocarcinomas have distinct profiles of microsatellite instability, PTEN expression, and ARID1A expression by Huang, Hsien-Neng, Lin, Ming-Chieh, Tseng, Li-Hui, Chiang, Ying-Cheng, Lin, Liang-In, Lin, Yu-Feng, Huang, Hsin-Ying, Kuo, Kuan-Ting

“…Aims To understand the role of and differences in molecular alterations between endometrial and ovarian endometrioid adenocarcinomas. Methods and results We…”
Get full text

Significance of histone methyltransferase SETDB1 expression in colon adenocarcinoma by Ho, Yi‐Jung, Lin, Yueh‐Min, Huang, Yen‐Chi, Chang, Jungshan, Yeh, Kun‐Tu, Lin, Liang‐In, Gong, Zhiyuan, Tzeng, Tsai‐Yu, Lu, Jeng‐Wei

“…This study investigated the clinical implications of SETDB1 (also known as KMT1E) in human colon adenocarcinoma. Expression levels of SETDB1 proteins were…”
Get full text

Hyperleukocytosis is associated with distinct genetic alterations and is an independent poor‐risk factor in de novo acute myeloid leukemia patients by Tien, Feng‐Ming, Hou, Hsin‐An, Tsai, Cheng‐Hong, Tang, Jih‐Luh, Chen, Chien‐Yuan, Kuo, Yuan‐Yeh, Li, Chi‐Cheng, Lin, Chien‐Ting, Yao, Ming, Huang, Shang‐Yi, Ko, Bor‐Sheng, Hsu, Szu‐Chun, Wu, Shang‐Ju, Tsay, Woei, Tseng, Mei‐Hsuan, Liu, Ming‐Chih, Liu, Chia‐Wen, Lin, Liang‐In, Chou, Wen‐Chien, Tien, Hwei‐Fang

“…Objectives Acute myeloid leukemia (AML) with hyperleukocytosis (HL) is intuitively thought as a unique group with dismal prognosis. However, comprehensive…”
Get full text

Exacerbation of Liver Tumor Metastasis in twist1a+/xmrk+ Double Transgenic Zebrafish following Lipopolysaccharide or Dextran Sulphate Sodium Exposure by Lu, Jeng-Wei, Sun, Yuxi, Lin, Liang-In, Liu, Dong, Gong, Zhiyuan

“…The poor prognosis for patients with hepatocellular carcinoma (HCC) is related directly to metastasis. The Twist1 gene encodes for a transcription factor…”
Get full text

Concomitant WT1 mutations predict poor prognosis in acute myeloid leukemia patients with double mutant CEBPA by Tien, Feng-Ming, Hou, Hsin-An, Tang, Jih-Luh, Kuo, Yuan-Yeh, Chen, Chien-Yuan, Tsai, Cheng-Hong, Yao, Ming, Lin, Chien-Ting, Li, Chi-Cheng, Huang, Shang-Yi, Ko, Bor-Sheng, Hsu, Szu-Chun, Wu, Shang-Ju, Liu, Jia-Hau, Chou, Sheng Chieh, Tsay, Woei, Tseng, Mei-Hsuan, Liu, Ming-Chih, Liu, Chia-Wen, Lin, Liang-In, Chou, Wen-Chien, Tien, Hwei-Fang

Get full text

Distinct clinico-biological features in AML patients with low allelic ratio FLT3-ITD: role of allogeneic stem cell transplantation in first remission by Tien, Feng-Ming, Tsai, Cheng-Hong, Huang, Sheng-Chuan, Liu, Jia-Hau, Chen, Chien-Yuan, Kuo, Yuan-Yeh, Chuang, Yi-Kuang, Tseng, Mei-Hsuan, Peng, Yen-Ling, Liu, Ming-Chih, Liu, Chia-Wen, Liao, Xiu-Wen, Lin, Liang-In, Wu, Yu-Sin, Hou, Mei-Fang, Wu, Shang-Ju, Hsu, Szu-Chun, Ko, Bor-Sheng, Chou, Wen-Chien, Yao, Ming, Hou, Hsin-An, Tang, Jih-Luh, Tien, Hwei-Fang

“…The mutant burden of FLT3 -ITD modulates its prognostic impact on patients with acute myeloid leukemia (AML). However, for patients with low allelic ratio (AR)…”
Get full text

Aberrant expression of annexin A10 is closely related to gastric phenotype in serrated pathway to colorectal carcinoma by Tsai, Jia-Huei, Lin, Yu-Lin, Cheng, Yi-Chen, Chen, Chien-Chuan, Lin, Liang-In, Tseng, Li-Hui, Cheng, Mei-Ling, Liau, Jau-Yu, Jeng, Yung-Ming

“…Annexin A10 (ANXA10) is a member of the ANX family that is normally expressed in gastric mucosa. ANXA10 was recently observed to be upregulated in sessile…”
Get full text

Vertical blockade of the IGFR- PI3K/Akt/mTOR pathway for the treatment of hepatocellular carcinoma: the role of survivin by Ou, Da-Liang, Lee, Bin-Shyun, Lin, Liang-In, Liou, Jun-Yang, Liao, Sheng-Chieh, Hsu, Chiun, Cheng, Ann-Lii

“…To explore whether combining inhibitors that target the insulin-like growth factor receptor (IGFR)/PI3K/Akt/mTOR signaling pathway (vertical blockade) can…”
Get full text

Validation of the molecular international prognostic scoring system in patients with myelodysplastic syndromes defined by international consensus classification by Lee, Wan-Hsuan, Tsai, Ming-Tao, Tsai, Cheng-Hong, Tien, Feng-Ming, Lo, Min-Yen, Tseng, Mei-Hsuan, Kuo, Yuan-Yeh, Liu, Ming-Chih, Yang, Yi-Tsung, Chen, Jui-Che, Tang, Jih-Luh, Sun, Hsun-I, Chuang, Yi-Kuang, Lin, Liang-In, Chou, Wen-Chien, Lin, Chien-Chin, Hou, Hsin-An, Tien, Hwei-Fang

“…Myelodysplastic syndromes (MDS) have varied prognoses and require a risk-adapted treatment strategy for treatment optimization. Recently, a molecular…”
Get full text

Cytarabine-Resistant FLT3 -ITD Leukemia Cells are Associated with TP53 Mutation and Multiple Pathway Alterations-Possible Therapeutic Efficacy of Cabozantinib by Ko, Ya-Chen, Hu, Chung-Yi, Liu, Zheng-Hau, Tien, Hwei-Fang, Ou, Da-Liang, Chien, Hsiung-Fei, Lin, Liang-In

“…Internal tandem duplication of FLT3 juxtamembrane domain (FLT3-ITD)-positive acute myeloid leukemia (AML) leads to poor clinical outcomes after chemotherapy…”
Get full text

Autophagy: Resetting glutamine-dependent metabolism and oxygen consumption by Lin, Tsung-Chin, Chen, Yun-Ru, Kensicki, Elizabeth, Li, Angela Ying-Jian, Kong, Mei, Li, Yang, Mohney, Robert P., Shen, Han-Ming, Stiles, Bangyan, Mizushima, Noboru, Lin, Liang-In, Ann, David K.

“…Autophagy is a catabolic process that functions in recycling and degrading cellular proteins, and is also induced as an adaptive response to the increased…”
Get full text

DNA polymerase I proofreading exonuclease activity is required for endonuclease V repair pathway both in vitro and in vivo by Su, Kang-Yi, Lin, Liang-In, Goodman, Steven D., Yen, Rong-Syuan, Wu, Cho-Yuan, Chang, Wei-Chen, Yang, Ya-Chien, Cheng, Wern-Cherng, Fang, Woei-horng

“…•A phagemid-based deoxyinosine substrate can be repaired by minimal component reconstitute assay with endo V, polI and ligase.•The phagemid-based deoxyinosine…”
Get full text

KRAS mutation is a predictor of oxaliplatin sensitivity in colon cancer cells by Lin, Yu-Lin, Liau, Jau-Yu, Yu, Shan-Chi, Ou, Da-Liang, Lin, Liang-In, Tseng, Li-Hui, Chang, Yih-Leong, Yeh, Kun-Huei, Cheng, Ann-Lii

“…Molecular biomarkers to determine the effectiveness of targeted therapies in cancer treatment have been widely adopted in colorectal cancer (CRC), but those to…”
Get full text

RUNX1 gene mutation in primary myelodysplastic syndrome – the mutation can be detected early at diagnosis or acquired during disease progression and is associated with poor outcome by Chen, Chien‐Yuan, Lin, Liang‐In, Tang, Jih‐Luh, Ko, Bo‐Sheng, Tsay, Woei, Chou, Wen‐Chien, Yao, Ming, Wu, Shang‐Ju, Tseng, Mei‐Hsuan, Tien, Hwei‐Fang

“…Summary Mutations of Runt‐related transcription factor 1 (RUNX1) have been detected in patients with myelodysplastic syndrome (MDS). However, the prognostic…”
Get full text