Search Results - "Liang, Yongju"
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Synthesis and antitumor activity of novel quinazoline derivatives containing thiosemicarbazide moiety
Published in European journal of medicinal chemistry (01-08-2012)“…Series of novel derivatives of quinazoline containing thiosemicarbazide moiety 5 and 9 have been synthesized and tested for their antitumor activities in vitro…”
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Emodin azide methyl anthraquinone derivative triggers mitochondrial-dependent cell apoptosis involving in caspase-8-mediated Bid cleavage
Published in Molecular cancer therapeutics (01-06-2008)“…AMAD, an emodin azide methyl anthraquinone derivative, was extracted from the nature giant knotweed rhizome of traditional Chinese herbs. Here, we investigated…”
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The tumor suppressive role of NUMB isoform 1 in esophageal squamous cell carcinoma
Published in Oncotarget (30-07-2014)“…Esophageal quamous cell carcinoma (ESCC) is the predominant histological type of esophageal carcinoma in Asian populations. To date, few biomarkers have been…”
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Efficient synthesis and biological evaluation of 1,3-benzenedicarbonyl dithioureas
Published in Bioorganic & medicinal chemistry letters (15-02-2011)“…The synthesis and biological activity of 1,3-benzenedicarbonyl dithioureas are described. Bioassay results indicated that these compounds exhibited…”
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Characterization of tetrandrine, a potent inhibitor of P-glycoprotein-mediated multidrug resistance
Published in Cancer chemotherapy and pharmacology (01-04-2004)“…Multidrug resistance (MDR) is one of the main obstacles in tumor chemotherapy. A promising approach to solving this problem is to utilize a nontoxic and potent…”
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Cytotoxic Diterpenoids from the Soft Coral Sarcophyton crassocaule
Published in Journal of natural products (Washington, D.C.) (01-10-2006)“…Five new cembrane diterpenoids, sarcrassins A−E (1−5) along with a known compound, emblide (6), have been isolated from the soft coral Sarcophyton crassocaule…”
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Synthesis and cytotoxicity of O, O′-dialkyl {[2-(substituted phenoxy)acetamido](substituted phenyl)methyl}phosphonates
Published in European journal of medicinal chemistry (01-02-2012)“…A series of O, O′-dialkyl {[2-(substituted phenoxy)acetamido](substituted phenyl)methyl}phosphonates was synthesized and their cytotoxic activities were tested…”
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