Search Results - "Liang, Yaoji"

Gut stem cell necroptosis by genome instability triggers bowel inflammation by Wang, Ruicong, Li, Hongda, Wu, Jianfeng, Cai, Zhi-Yu, Li, Baizhou, Ni, Hengxiao, Qiu, Xingfeng, Chen, Hui, Liu, Wei, Yang, Zhang-Hua, Liu, Min, Hu, Jin, Liang, Yaoji, Lan, Ping, Han, Jiahuai, Mo, Wei

“…The aetiology of inflammatory bowel disease (IBD) is a multifactorial interplay between heredity and environment 1 , 2 . Here we report that deficiency in…”
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ZBP1 mediates interferon-induced necroptosis by Yang, Daowei, Liang, Yaoji, Zhao, Shubo, Ding, Yan, Zhuang, Qiuyu, Shi, Qilin, Ai, Tingting, Wu, Su-Qin, Han, Jiahuai

“…Interferons (IFNs) play an important role in immunomodulatory and antiviral functions. IFN-induced necroptosis has been reported in cells deficient in…”
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RIP3 targets pyruvate dehydrogenase complex to increase aerobic respiration in TNF-induced necroptosis by Yang, Zhentao, Wang, Yan, Zhang, Yingying, He, Xiadi, Zhong, Chuan-Qi, Ni, Hengxiao, Chen, Xin, Liang, Yaoji, Wu, Jianfeng, Zhao, Shimin, Zhou, Dawang, Han, Jiahuai

“…Receptor-interacting protein kinase 3 (RIP3)-regulated production of reactive oxygen species (ROS) positively feeds back on tumour necrosis factor…”
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Rapid detection of the irinotecan-related UGT1A1 & 5-fluorouracil related DPYD polymorphism by asymmetric polymerase chain reaction melting curve analysis by Lian, Jiabian, Liang, Yaoji, Wang, Yunling, Chen, Ying, Li, Xun, Xia, Lu

“…•Introduction of a novel PCR melting curve analysis method for rapid detection of DPYD and UGT1A1 polymorphisms related to fluorouracil and irinotecan…”
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RIP1/RIP3 Binding to HSV-1 ICP6 Initiates Necroptosis to Restrict Virus Propagation in Mice by Huang, Zhe, Wu, Su-Qin, Liang, Yaoji, Zhou, Xiaojuan, Chen, Wanze, Li, Lisheng, Wu, Jianfeng, Zhuang, Qiuyu, Chen, Chang’an, Li, Jingxian, Zhong, Chuan-Qi, Xia, Weixiang, Zhou, Rongbin, Zheng, Chunfu, Han, Jiahuai

“…Necroptosis is a form of programmed necrosis that is mediated by signaling complexes containing the receptor-interacting protein 3 (RIP3) and RIP1 kinases. We…”
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Author Correction: RIP3 targets pyruvate dehydrogenase complex to increase aerobic respiration in TNF-induced necroptosis by Yang, Zhentao, Wang, Yan, Zhang, Yingying, He, Xiadi, Zhong, Chuan-Qi, Ni, Hengxiao, Chen, Xin, Liang, Yaoji, Wu, Jianfeng, Zhao, Shimin, Zhou, Dawang, Han, Jiahuai

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Development and characterization of anti-IL-5 monoclonal antibody Fab fragment for blocking IL-5/IL-5Rα binding by Li, Shijie, Wang, Shijie, Fordjour, Eric, Liang, Yaoji, Wang, Xuelian, Ye, Yonghao, Bai, Zhonghu, Yang, Yankun, Chen, Yongqi

“…•20A12-Fab was successfully obtained with high affinity and blocking activity, making it suitable for inhalation administration.•During Fab humanization, two…”
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Nucleoporin Seh1 Interacts with Olig2/Brd7 to Promote Oligodendrocyte Differentiation and Myelination by Liu, Zhixiong, Yan, Minbiao, Liang, Yaoji, Liu, Min, Zhang, Kun, Shao, Dandan, Jiang, Rencai, Li, Li, Wang, Chaomeng, Nussenzveig, Daniel R., Zhang, Kunkun, Chen, Shaoxuan, Zhong, Chuanqi, Mo, Wei, Fontoura, Beatriz M.A., Zhang, Liang

“…Nucleoporins (Nups) are involved in neural development, and alterations in Nup genes are linked to human neurological diseases. However, physiological…”
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Ppm1b negatively regulates necroptosis through dephosphorylating Rip3 by Chen, Wanze, Wu, Jianfeng, Li, Lisheng, Zhang, Zhengmao, Ren, Junming, Liang, Yaoji, Chen, Fenfang, Yang, Chao, Zhou, Zhenru, Sean Su, Sheng, Zheng, Xinru, Zhang, Zhirong, Zhong, Chuan-Qi, Wan, Haoqiang, Xiao, Mu, Lin, Xia, Feng, Xin-Hua, Han, Jiahuai

“…The auto-phosphorylation of murine receptor-interacting protein 3 (Rip3) on Thr 231 and Ser 232 in the necrosome is required to trigger necroptosis. However,…”
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Inactivation of Cyclic AMP Response Element Transcription Caused by Constitutive p38 Activation Is Mediated by Hyperphosphorylation-Dependent CRTC2 Nucleocytoplasmic Transport by Ma, Huabin, Liu, Zeyuan, Zhong, Chuan-Qi, Liu, Yifei, Zhang, Zhirong, Liang, Yaoji, Li, Jingxian, Han, Shoufa, Han, Jiahuai

“…The p38 signal transduction pathway can be activated transiently or constitutively, depending on the contexts in which the activation occurs. However, the…”
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Targeting HSV-1 protein ICP6 by RIP1 and RIP3 initiates necroptosis to restrict HSV-1 propagation in mice (VIR9P.1159) by Huang, Zhe, Wu, Suqin, Liang, Yaoji, Han, Jiahuai

“…Abstract Necroptosis is a type of programmed necrosis that participates in host defense to eliminate certain pathogens. We show that receptor interacting…”
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RIP3 is involved in host defense against HSV-1 infection via enhancing STING mediated antiviral signaling (P1405) by Liang, Yaoji, Wu, Suqin, Han, Jiahuai

“…Abstract Herpes simplex virus type 1 (HSV-1), a double stranded DNA virus, is a widespread virus that infects approximately 80% of adults worldwide. HSV-1…”
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The Gβγ-Src signaling pathway regulates TNF-induced necroptosis via control of necrosome translocation by Li, Lisheng, Chen, Wanze, Liang, Yaoji, Ma, Huabin, Li, Wenjuan, Zhou, Zhenru, Li, Jie, Ding, Yan, Ren, Junming, Lin, Juan, Han, Felicia, Wu, Jianfeng, Han, Jiahuai

“…Formation of multi-component signaling complex necrosomes is essential for tumor necrosis factor α (TNF)-induced programmed necrosis (also called necroptosis)…”
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Recognition of cytosolic DNA attenuates glucose metabolism and induces AMPK mediated energy stress response by Zheng, Min, Xie, Linna, Liang, Yaoji, Wu, Suqin, Xu, Huijuan, Zhang, Yuedong, Liu, Hekun, Lin, Dexin, Han, Jiahuai, Lu, Kunping

“…Both viral infection and DNA transfection expose single-stranded or double-stranded DNA to the cytoplasm of mammalian cells. Recognition of cytosolic DNA…”
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The G[beta][gamma]-Src signaling pathway regulates TNF-induced necroptosis via control of necrosome translocation by Li, Lisheng, Chen, Wanze, Liang, Yaoji, Ma, Huabin, Li, Wenjuan, Zhou, Zhenru, Li, Jie, Ding, Yan, Ren, Junming, Lin, Juan, Han, Felicia, Wu, Jianfeng, Han, Jiahuai

“…Formation of multi-component signaling complex necrosomes is essential for tumor necrosis factor α (TNF)-induced programmed necrosis (also called necroptosis)…”
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The Gβy-Src signaling pathway regulates TNF-induced necroptosis via control of necrosome translocation by Lisheng Li Wanze Chen Yaoji Liang Huabin Ma Wenjuan Li Zhenru Zhou Jie Li Yan Ding Junming Ren Juan Lin Felicia Han Jianfeng Wu Jiahuai Han

“…Formation of multi-component signaling complex necrosomes is essential for tumor necrosis factor a （TNF）-induced programmed necrosis （also called necroptosis）…”
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