Search Results - "Liang, Xing"
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Mechanisms underlying the protective effects of mesenchymal stem cell-based therapy
Published in Cellular and molecular life sciences : CMLS (01-07-2020)“…Mesenchymal stem cells (MSCs) have been extensively investigated for the treatment of various diseases. The therapeutic potential of MSCs is attributed to…”
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BODIPY as a Multifunctional Theranostic Reagent in Biomedicine: Self‐Assembly, Properties, and Applications
Published in Advanced materials (Weinheim) (01-05-2023)“…The use of boron dipyrromethene (BODIPY) in biomedicine is reviewed. To open, its synthesis and regulatory strategies are summarized, and inspiring…”
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Advances in Application of Azobenzene as a Trigger in Biomedicine: Molecular Design and Spontaneous Assembly
Published in Advanced materials (Weinheim) (01-07-2021)“…Azobenzene is a well‐known derivative of stimulus‐responsive molecular switches and has shown superior performance as a functional material in biomedical…”
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Extracellular Vesicles‐Derived Hybrid Nanoplatforms for Amplified CD47 Blockade‐Based Cancer Immunotherapy
Published in Advanced materials (Weinheim) (01-09-2023)“…Immunomodulation of tumor‐associated macrophages (TAMs) into tumor‐inhibiting M1‐like phenotype is a promising but challenging strategy. Cleverly, tumor cells…”
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Fighting against Drug‐Resistant Tumors using a Dual‐Responsive Pt(IV)/Ru(II) Bimetallic Polymer
Published in Advanced materials (Weinheim) (01-10-2020)“…Drug resistance is a major problem in cancer treatment. Herein, the design of a dual‐responsive Pt(IV)/Ru(II) bimetallic polymer (PolyPt/Ru) to treat…”
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Optimization and Design of Magnetic Ferrite Nanoparticles with Uniform Tumor Distribution for Highly Sensitive MRI/MPI Performance and Improved Magnetic Hyperthermia Therapy
Published in Nano letters (12-06-2019)“…Two major technical challenges of magnetic hyperthermia are quantitative assessment of agent distribution during and following administration and achieving…”
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RNAi therapeutic and its innovative biotechnological evolution
Published in Biotechnology advances (01-09-2019)“…Recently, United States Food and Drug Administration (FDA) and European Commission (EC) approved Alnylam Pharmaceuticals' RNA interference (RNAi) therapeutic,…”
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Dual Drug Backboned Shattering Polymeric Theranostic Nanomedicine for Synergistic Eradication of Patient‐Derived Lung Cancer
Published in Advanced materials (Weinheim) (01-03-2018)“…Most of the current nanoparticle‐based therapeutics worldwide failing in clinical trials face three major challenges: (i) lack of an optimum drug delivery…”
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Site‐Selective δ‐C(sp3)−H Alkylation of Amino Acids and Peptides with Maleimides via a Six‐Membered Palladacycle
Published in Angewandte Chemie International Edition (14-05-2018)“…The site‐selective functionalization of unactivated C(sp3)−H bonds remains one of the greatest challenges in organic synthesis. Herein, we report on the…”
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Lipid Nanoparticles Optimized for Targeting and Release of Nucleic Acid
Published in Advanced materials (Weinheim) (01-01-2024)“…Lipid nanoparticles (LNPs) are currently the most promising clinical nucleic acids drug delivery vehicles. LNPs prevent the degradation of cargo nucleic acids…”
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Terrylenediimide-Based Intrinsic Theranostic Nanomedicines with High Photothermal Conversion Efficiency for Photoacoustic Imaging-Guided Cancer Therapy
Published in ACS nano (25-04-2017)“…Activatable theranostic nanomedicines involved in photothermal therapy (PTT) have received constant attention as promising alternatives to traditional…”
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Brain Co‐Delivery of Temozolomide and Cisplatin for Combinatorial Glioblastoma Chemotherapy
Published in Advanced materials (Weinheim) (01-08-2022)“…Glioblastoma (GBM) is an intractable malignancy with high recurrence and mortality. Combinatorial therapy based on temozolomide (TMZ) and cisplatin (CDDP)…”
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Thermo-responsive triple-function nanotransporter for efficient chemo-photothermal therapy of multidrug-resistant bacterial infection
Published in Nature communications (24-09-2019)“…New strategies with high antimicrobial efficacy against multidrug-resistant bacteria are urgently desired. Herein, we describe a smart triple-functional…”
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Visible light-induced direct α C–H functionalization of alcohols
Published in Nature communications (28-01-2019)“…Considering the synthetic value of introducing active alcoholic hydroxyl group, developing C–H functionalization of alcohols is of significance. Herein, we…”
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Aggregation-Induced Emission: Lighting up Cells, Revealing Life
Published in Small (Weinheim an der Bergstrasse, Germany) (01-12-2016)“…Understanding metabolism and dynamic biological events in cells, as well as physiological functions and pathological changes in organisms, is the major goal of…”
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Clinical advances of siRNA therapeutics
Published in The journal of gene medicine (01-07-2019)“…Small interfering RNA (siRNA) enables efficient target gene silencing by employing a RNA interference (RNAi) mechanism, which can compromise gene expression…”
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Ultrasmall gold nanoparticles in cancer diagnosis and therapy
Published in Theranostics (01-01-2020)“…Due to their lower systemic toxicity, faster kidney clearance and higher tumor accumulation, ultrasmall gold nanoparticles (less than 10 nm in diameter) have…”
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Phase field simulation of powder bed-based additive manufacturing
Published in Acta materialia (01-02-2018)“…Quality control in parts built layer-by-layer via Additive Manufacturing (AM) process is still a challenge since critical features, such as the control in…”
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The challenge and prospect of mRNA therapeutics landscape
Published in Biotechnology advances (01-05-2020)“…Messenger RNA (mRNA)-based therapeutics hold the potential to cause a major revolution in the pharmaceutical industry because they can be used for precise and…”
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Gold nanoparticles: Emerging paradigm for targeted drug delivery system
Published in Biotechnology advances (01-09-2013)“…The application of nanotechnology in medicine, known as nanomedicine, has introduced a plethora of nanoparticles of variable chemistry and design…”
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