Search Results - "Liang, Wei‐Zhe"
-
1
Mechanisms underlying protective effects of vitamin E against mycotoxin deoxynivalenol‐induced oxidative stress and its related cytotoxicity in primary human brain endothelial cells
Published in Environmental toxicology (01-07-2021)“…Fusarium mycotoxins are one of the largest families of mycotoxins. Among these mycotoxins, deoxynivalenol is the most widespread pollutant of grains. However,…”
Get full text
Journal Article -
2
Investigation of the mechanisms behind ochratoxin A‐induced cytotoxicity in human astrocytes and the protective effects of N‐acetylcysteine
Published in Journal of applied toxicology (01-09-2024)“…Ochratoxin A (OTA) is a type of mycotoxin commonly found in raw and processed foods. It is essential to be aware of this toxin, as it can harm your health if…”
Get full text
Journal Article -
3
Involvement of oxidative stress‐related apoptosis in chlorpyrifos‐induced cytotoxicity and the ameliorating potential of the antioxidant vitamin E in human glioblastoma cells
Published in Environmental toxicology (01-09-2023)“…Organophosphate pesticides (OPs), which are among the most widely used synthetic chemicals for the control of a wide variety of pests, are however associated…”
Get full text
Journal Article -
4
Mechanism of action of a diterpene alkaloid hypaconitine on cytotoxicity and inhibitory effect of BAPTA‐AM in HCN‐2 neuronal cells
Published in Clinical and experimental pharmacology & physiology (01-05-2021)“…Hypaconitine, a neuromuscular blocker, is a diterpene alkaloid found in the root of Aconitum carmichaelii. Although hypaconitine was shown to affect various…”
Get full text
Journal Article -
5
Exploring the impact of a naturally occurring sapogenin diosgenin on underlying mechanisms of Ca2+ movement and cytotoxicity in human prostate cancer cells
Published in Environmental toxicology (01-03-2020)“…Literature has shown that diosgenin, a naturally occurring sapogenin, inducedcytotoxic effects in many cancer models. This study investigated the effect of…”
Get full text
Journal Article -
6
Investigation of cytotoxic effect of the bufanolide steroid compound cinobufagin and its related underlying mechanism in brain cell models
Published in Journal of biochemical and molecular toxicology (01-10-2021)“…Cinobufagin, a bufadienolide of toad venom of Bufo bufo gargarizans, is used as a cardiotonic, central nervous system (CNS) respiratory agent, as well as an…”
Get full text
Journal Article -
7
Impact of parallax and interpupillary distance on size judgment performances of virtual objects in stereoscopic displays
Published in Ergonomics (02-01-2019)“…Effective interactions in both real and stereoscopic environments require accurate perceptions of size and position. This study investigated the effects of…”
Get full text
Journal Article -
8
Mechanisms underlying the effect of an oral antihyperglycaemic agent glyburide on calcium ion (Ca2+) movement and its related cytotoxicity in prostate cancer cells
Published in Clinical and experimental pharmacology & physiology (01-01-2020)“…Summary Glyburide is an agent commonly used to treat type 2 diabetes and also affects various physiological responses in different models. However, the effect…”
Get full text
Journal Article -
9
Evaluation of cytotoxicity of propofol and its related mechanism in glioblastoma cells and astrocytes
Published in Environmental toxicology (01-12-2017)“…Propofol (2,6‐diisopropylphenol), one of the extensively and commonly used anesthetic agents, has been shown to affect the biological behavior of various…”
Get full text
Journal Article -
10
Protective effects of a phenolic glycoside compound curculigoside on H2O2-induced oxidative stress and cytotoxicity in normal human breast epithelial cells
Published in Journal of functional foods (01-02-2018)“…•Protective effects of curculigoside were explored in human breast epithelial cells.•Curculigoside protected H2O2-induced oxidative stress.•Curculigoside…”
Get full text
Journal Article -
11
Selective cytotoxic effects of low-power laser irradiation on human oral cancer cells
Published in Lasers in surgery and medicine (01-11-2015)“…Background and Objectives Low‐power laser irradiation (LPLI) is known to regulate cell proliferation and migration in clinical use. Recent studies have shown…”
Get full text
Journal Article -
12
The involvement of mitochondrial apoptotic pathway in eugenol-induced cell death in human glioblastoma cells
Published in Toxicology letters (05-01-2015)“…[Display omitted] •We explored the effect of eugenol on human glioblastoma cells.•Eugenol induced Ca2+ movement including Ca2+ release and Ca2+ entry.•Eugenol…”
Get full text
Journal Article -
13
The protective effects of the antioxidant N-acetylcysteine (NAC) against oxidative stress-associated apoptosis evoked by the organophosphorus insecticide malathion in normal human astrocytes
Published in Toxicology (Amsterdam) (01-04-2019)“…[Display omitted] •Exploring the mechanism underlying the effects of malathion on cytotoxicity in Gibco® Human Astrocytes (GHA cells).•In GHA cells, malathion…”
Get full text
Journal Article -
14
Investigation of Cytotoxicity and Oxidative Stress Induced by the Pyrethroid Bioallethrin in Human Glioblastoma Cells: The Protective Effect of Vitamin E (VE) and Its Underlying Mechanism
Published in Chemical research in toxicology (16-05-2022)“…Bioallethrin belongs to the family of pyrethroid insecticides. Previous studies have shown that bioallethrin affected the function of muscarinic receptor and…”
Get full text
Journal Article -
15
Exploration of beauvericin's toxic effects and mechanisms in human astrocytes and N-acetylcysteine's protective role
Published in Toxicon (Oxford) (28-05-2024)“…Beauvericin (BEA) is a newly identified mycotoxin produced by various Fusarium species, and its contamination in food and animal feed is widespread globally…”
Get full text
Journal Article -
16
Induction of Ca 2+ signaling and cytotoxic responses of human lung fibroblasts upon an antihistamine drug oxatomide treatment and evaluating the protective effects of Ca 2+ chelating
Published in Fundamental & clinical pharmacology (21-10-2024)“…Oxatomide, an antihistamine drug of the diphenylmethylpiperazine family, has anti-inflammatory effects in airway disease. Because oxatomide was shown to cause…”
Get full text
Journal Article -
17
The Impact of the Antipsychotic Medication Chlorpromazine on Cytotoxicity through Ca2+ Signaling Pathway in Glial Cell Models
Published in Neurotoxicity research (01-06-2022)“…Chlorpromazine, an antipsychotic medication, is conventionally applied to cope with the psychotic disorder such as schizophrenia. In cellular studies,…”
Get full text
Journal Article -
18
Evaluation of the mycotoxin patulin on cytotoxicity and oxidative stress in human glioblastoma cells and investigation of protective effect of the antioxidant N-acetylcysteine (NAC)
Published in Toxicon (Oxford) (01-01-2023)“…Mycotoxins are secondary metabolites produced by various kinds of fungi that can induce disease in humans. The fungal species Penicillium expansum produces…”
Get full text
Journal Article -
19
Cytotoxic effects of gastrodin extracted from the rhizome of Gastrodia elata Blume in glioblastoma cells, but not in normal astrocytes, via the induction of oxidative stress-associated apoptosis that involved cell cycle arrest and p53 activation
Published in Food and chemical toxicology (01-09-2017)“…Researches have been conducted to explore the biological effect of gastrodin, a natural compound extracted from the rhizome of Gastrodia elata Blume, in…”
Get full text
Journal Article -
20
Ca2+ signaling as a mechanism of haloperidol-induced cytotoxicity in human astrocytes and assessing the protective role of a Ca2+ chelator
Published in Naunyn-Schmiedeberg's archives of pharmacology (01-11-2020)“…Haloperidol, a typical antipsychotic medication, has been shown to possess various biological effects in different brain models. However, the impact of…”
Get full text
Journal Article