Search Results - "Liang, Wanling"

Pulmonary delivery of therapeutic siRNA by Lam, Jenny Ka-Wing, Liang, Wanling, Chan, Hak-Kim

“…Small interfering RNA (siRNA) has a huge potential for the treatment or prevention of various lung diseases. Once the RNA molecules have successfully entered…”
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Pulmonary Delivery of Biological Drugs by Liang, Wanling, Pan, Harry W, Vllasaliu, Driton, Lam, Jenny K W

“…In the last decade, biological drugs have rapidly proliferated and have now become an important therapeutic modality. This is because of their high potency,…”
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Ursolic Acid Regulates Cell Cycle and Proliferation in Colon Adenocarcinoma by Suppressing Cyclin B1 by Yang, Minhui, Hu, Changxiao, Cao, Yibo, Liang, Wanling, Yang, Xiangdong, Xiao, Tianbao

“…The biological functions of cyclin B1 (CCNB1) in colon adenocarcinoma (COAD) will be explored in this study. Furthermore, the therapeutic effects and potential…”
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Delivery of RNAi Therapeutics to the Airways-From Bench to Bedside by Qiu, Yingshan, Lam, Jenny K W, Leung, Susan W S, Liang, Wanling

“…RNA interference (RNAi) is a potent and specific post-transcriptional gene silencing process. Since its discovery, tremendous efforts have been made to…”
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Incorporation of a Nuclear Localization Signal in pH Responsive LAH4-L1 Peptide Enhances Transfection and Nuclear Uptake of Plasmid DNA by Xu, Yingying, Liang, Wanling, Qiu, Yingshan, Cespi, Marco, Palmieri, Giovanni F, Mason, A. James, Lam, Jenny K. W

“…The major intracellular barriers associated with DNA delivery using nonviral vectors are inefficient endosomal/lysosomal escape and poor nuclear uptake…”
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Meta-Analysis of Hepatic Arterial Infusion for Liver Metastases From Colorectal Cancer by Zhang, Yan, Wang, Kaili, Yang, Tao, Cao, Yibo, Liang, Wanling, Yang, Xiangdong, Xiao, Tianbao

“…The aim of the present study was to evaluate the potential benefits of hepatic arterial infusion chemotherapy (HAIC) in the management of colorectal liver…”
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Spray freeze drying of small nucleic acids as inhaled powder for pulmonary delivery by Liang, Wanling, Chan, Alan Y.L., Chow, Michael Y.T., Lo, Fiona F.K., Qiu, Yingshan, Kwok, Philip C.L., Lam, Jenny K.W.

“…The therapeutic potential of small nucleic acids such as small interfering RNA (siRNA) to treat lung diseases has been successfully demonstrated in many in…”
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Synthesis, Structure⁻Activity Relationships and In Vitro Toxicity Profile of Lactose-Based Fatty Acid Monoesters as Possible Drug Permeability Enhancers by Lucarini, Simone, Fagioli, Laura, Cavanagh, Robert, Liang, Wanling, Perinelli, Diego Romano, Campana, Mario, Stolnik, Snjezana, Lam, Jenny K W, Casettari, Luca, Duranti, Andrea

“…Permeability enhancers are receiving increased attention arising from their ability to increase transepithelial permeability and thus, bioavailability of…”
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Formulation of pH responsive peptides as inhalable dry powders for pulmonary delivery of nucleic acids by Liang, Wanling, Kwok, Philip C.L., Chow, Michael Y.T., Tang, Patricia, Mason, A. James, Chan, Hak-Kim, Lam, Jenny K.W.

“…[Display omitted] Nucleic acids have the potential to be used as therapies or vaccines for many different types of disease, but delivery remains the most…”
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Gliotoxin Inhibits Proliferation and Induces Apoptosis in Colorectal Cancer Cells by Chen, Junxiong, Wang, Chenliang, Lan, Wenjian, Huang, Chunying, Lin, Mengmeng, Wang, Zhongyang, Liang, Wanling, Iwamoto, Aikichi, Yang, Xiangling, Liu, Huanliang

“…The discovery of new bioactive compounds from marine natural sources is very important in pharmacological research. Here we developed a Wnt responsive…”
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Effective endogenous gene silencing mediated by pH responsive peptides proceeds via multiple pathways by Lam, Jenny K.W., Liang, Wanling, Lan, Yun, Chaudhuri, Poulami, Chow, Michael Y.T., Witt, Katarzyna, Kudsiova, Laila, Mason, A. James

“…Cationic amphipathic histidine rich peptides possess high plasmid DNA and siRNA delivery capabilities. To further understand the pH responsive siRNA delivery…”
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Theoretical Studies of MoS2 and Phosphorene Drug Delivery for Antituberculosis Drugs by Liang, Wanling, Luo, Xin

“…A systematic understanding of the interactions between the drug and 2D materials carrier at various physiological environments is essential for the development…”
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Theoretical Studies of MoS 2 and Phosphorene Drug Delivery for Antituberculosis Drugs by Liang, Wanling, Luo, Xin

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Engineering Pore Nanostructure of Carbon Cathodes for Zinc Ion Hybrid Supercapacitors by Jian, Wenbin, Zhang, Wenli, Wei, Xueer, Wu, Bingchi, Liang, Wanling, Wu, Ying, Yin, Jian, Lu, Ke, Chen, Yanan, Alshareef, Husam N., Qiu, Xueqing

“…Zinc ion hybrid supercapacitors (ZIHCs) with both high power density and high energy density have tremendous potential for energy storage applications such as…”
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Enzymatic Hydrolysis Lignin-Derived Porous Carbons through Ammonia Activation: Activation Mechanism and Charge Storage Mechanism by Jian, Wenbin, Zhang, Wenli, Wu, Bingchi, Wei, Xueer, Liang, Wanling, Zhang, Xiaoshan, Wen, Fuwang, Zhao, Lei, Yin, Jian, Lu, Ke, Qiu, Xueqing

“…The low energy density and low cost performance of electrochemical capacitors (ECs) are the principal factors that limit the wide applications of ECs. In this…”
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Using two-fluid nozzle for spray freeze drying to produce porous powder formulation of naked siRNA for inhalation by Liang, Wanling, Chow, Michael Y.T., Chow, Shing Fung, Chan, Hak-Kim, Kwok, Philip C.L., Lam, Jenny K.W.

“…[Display omitted] Spray freeze drying is an attractive technology to produce powder formulation for inhalation. It can be used to generate large porous…”
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KMT5A Knockdown Suppresses Osteosarcoma Cell Proliferation and Metastasis Through Ꞵ-Catenin Signalling by Zhang, Jin, An, Jiangdong, Wang, Zhaoheng, Wang, Keping, Liang, Wanling, Liu, Xiangyu, Zhou, Haiyu, Zhang, Haihong, Wang, Shuankev

“…Purpose: Osteosarcoma (OS) is the most common malignant solid bone tumor in children and young adults. We aimed to investigate the effects and cellular…”
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MiR-181c-5p Promotes Inflammatory Response during Hypoxia/Reoxygenation Injury by Downregulating Protein Tyrosine Phosphatase Nonreceptor Type 4 in H9C2 Cardiomyocytes by Cai, Yin, Xia, Zhengyuan, Ma, Haichun, Liang, Wanling, Ye, Xiaodong, Liu, Hao, Wang, Lin, Zhang, Dengwen, Ge, Liang, Wang, Sheng, Li, Jun

“…Background. Constitutive nuclear factor kappa B (NFκB) activation has been shown to exacerbate during myocardial ischemia/reperfusion (I/R) injury. We recently…”
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From Pulmonary Surfactant, Synthetic KL4 Peptide as Effective siRNA Delivery Vector for Pulmonary Delivery by Qiu, Yingshan, Chow, Michael Y. T, Liang, Wanling, Chung, Winnie W. Y, Mak, Judith C. W, Lam, Jenny K. W

“…Pulmonary delivery of small interfering RNA (siRNA) has huge potential for the treatment of a wide range of respiratory diseases. The ability of naked siRNA to…”
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Inhalable Dry Powder Formulations of siRNA and pH-Responsive Peptides with Antiviral Activity Against H1N1 Influenza Virus by Liang, Wanling, Chow, Michael Y. T, Lau, Pui Ngan, Zhou, Qi Tony, Kwok, Philip C. L, Leung, George P. H, Mason, A. James, Chan, Hak-Kim, Poon, Leo L. M, Lam, Jenny K. W

“…Pulmonary delivery of siRNA has considerable therapeutic potential for treating viral respiratory infectious diseases including influenza. By introducing siRNA…”
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