Search Results - "Liang, Wanfei"
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Dynamics of mcr-1 prevalence and mcr-1-positive Escherichia coli after the cessation of colistin use as a feed additive for animals in China: a prospective cross-sectional and whole genome sequencing-based molecular epidemiological study
Published in The Lancet. Microbe (01-05-2020)“…The global dissemination of colistin resistance encoded by mcr-1 has been attributed to extensive use of colistin in livestock, threatening colistin efficacy…”
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A new variant of the colistin resistance gene MCR-1 with co-resistance to β-lactam antibiotics reveals a potential novel antimicrobial peptide
Published in PLoS biology (01-12-2023)“…The emerging and global spread of a novel plasmid-mediated colistin resistance gene, mcr-1, threatens human health. Expression of the MCR-1 protein affects…”
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The Involvement of Mycobacterium Type III-A CRISPR-Cas System in Oxidative Stress
Published in Frontiers in microbiology (09-12-2021)“…Type I and type II CRISPR-Cas systems are employed to evade host immunity by targeting interference of bacteria's own genes. Although ( ), the causative agent…”
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A CRISPR-guided mutagenic DNA polymerase strategy for the detection of antibiotic-resistant mutations in M. tuberculosis
Published in Molecular therapy. Nucleic acids (13-09-2022)“…A sharp increase in multidrug-resistant tuberculosis (MDR-TB) threatens human health. Spontaneous mutation in essential gene confers an ability of…”
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MCR-1-dependent lipid remodelling compromises the viability of Gram-negative bacteria
Published in Emerging microbes & infections (01-12-2022)“…The global dissemination of the mobilized colistin resistance gene, mcr-1, threatens human health. Recent studies by our group and others have shown that the…”
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Single-Fluorescence ATP Sensor Based on Fluorescence Resonance Energy Transfer Reveals Role of Antibiotic-Induced ATP Perturbation in Mycobacterial Killing
Published in mSystems (28-06-2022)“…The rapid emergence of multidrug-resistant/extensively drug-resistant tuberculosis (TB) is responsible for treatment failure in patients with TB and…”
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Involvement of Transcription Elongation Factor GreA in Mycobacterium Viability, Antibiotic Susceptibility, and Intracellular Fitness
Published in Frontiers in microbiology (23-03-2020)“…There is growing evidence that GreA aids adaptation to stressful environments in various bacteria. However, the functions of GreA among mycobacteria remain…”
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Altered B cell immunoglobulin signature exhibits potential diagnostic values in human colorectal cancer
Published in iScience (17-03-2023)“…Antibody-secreting B cells have long been considered the central element of gut homeostasis; however, tumor-associated B cells in human colorectal cancer (CRC)…”
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A new variant of the colistin resistance gene MCR-1 with co-resistance to [beta]-lactam antibiotics reveals a potential novel antimicrobial peptide
Published in PLoS biology (13-12-2023)“…The emerging and global spread of a novel plasmid-mediated colistin resistance gene, mcr-1, threatens human health. Expression of the MCR-1 protein affects…”
Get full text
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Prediction of Antibiotic Resistance Evolution by Growth Measurement of All Proximal Mutants of Beta-Lactamase
Published in Molecular biology and evolution (03-05-2022)“…Abstract The antibiotic resistance crisis continues to threaten human health. Better predictions of the evolution of antibiotic resistance genes could…”
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