Search Results - "Liang, Shih‐Shin"
-
1
Assisted Reductive Amination for Quantitation of Tryptophan, 5-Hydroxytryptophan, and Serotonin by Ultraperformance Liquid Chromatography Coupled with Tandem Mass Spectrometry
Published in Molecules (Basel, Switzerland) (01-06-2023)“…Herein, we used isotopic formaldehyde and sodium cyanoborohydride via reductive amination to label two methyl groups on primary amine to arrange the standards…”
Get full text
Journal Article -
2
Protein-bound uremic toxins are associated with cognitive function among patients undergoing maintenance hemodialysis
Published in Scientific reports (31-12-2019)“…Patients with chronic kidney disease have a greater risk of cognitive impairment. Cerebral uremic solute accumulation causes uremic encephalopathy; however,…”
Get full text
Journal Article -
3
The relationship of indoxyl sulfate and p-cresyl sulfate with target cardiovascular proteins in hemodialysis patients
Published in Scientific reports (15-02-2021)“…Protein-bound uremic toxins (Indoxyl sulfate [IS] and p-cresyl sulfate [PCS]) are both associated with cardiovascular (CV) and all-cause mortality in subjects…”
Get full text
Journal Article -
4
How renal toxins respond to renal function deterioration and oral toxic adsorbent in pH‐controlled releasing capsule
Published in Environmental toxicology (01-07-2024)“…The number of patients with chronic kidney disease (CKD) is increasing. Oral toxin adsorbents may provide some value. Several uremic toxins, including indoxyl…”
Get full text
Journal Article -
5
DEHP mediates drug resistance by directly targeting AhR in human breast cancer
Published in Biomedicine & pharmacotherapy (01-01-2022)“…Resistance to chemotherapy and hormonal therapy is a major clinical problem in breast cancer medicine, especially for cancer metastasis and recurrence…”
Get full text
Journal Article -
6
Direct Binding of Cisplatin to p22phox, an Endoplasmic Reticulum (ER) Membrane Protein, Contributes to Cisplatin Resistance in Oral Squamous Cell Carcinoma (OSCC) Cells
Published in Molecules (Basel, Switzerland) (21-08-2020)“…Prolonged treatment with cisplatin (CDDP) frequently develops chemoresistance. We have previously shown that p22phox, an endoplasmic reticulum (ER) membrane…”
Get full text
Journal Article -
7
Reduced camptothecin sensitivity of estrogen receptor‐positive human breast cancer cells following exposure to di(2‐ethylhexyl)phthalate (DEHP) is associated with DNA methylation changes
Published in Environmental toxicology (01-04-2019)“…Di(2‐ethylhexyl)phthalate (DEHP) has been considered as an estrogen receptor alpha (ERα) agonist due to its ability to interact with ERα and promote the cell…”
Get full text
Journal Article -
8
Transmembrane and Coiled-Coil Domain 1 Impairs the AKT Signaling Pathway in Urinary Bladder Urothelial Carcinoma: A Characterization of a Tumor Suppressor
Published in Clinical cancer research (15-12-2017)“…Urinary bladder urothelial carcinoma (UBUC) is a common malignant disease in developed countries. Cell-cycle dysregulation resulting in uncontrolled cell…”
Get full text
Journal Article -
9
Synthesis of porous TiO2/SiO2 monodisperse hollow spheres as a platform for phosphopeptide enrichment
Published in Journal of porous materials (01-06-2024)“…A uniform dispersion of TiO 2 /SiO 2 hollow nanosphere of 290 nm with a high surface area of more than 100 m 2 g − 1 is prepared using polystyrene spheres as…”
Get full text
Journal Article -
10
Canned food intake and urinary bisphenol a concentrations: a randomized crossover intervention study
Published in Environmental science and pollution research international (01-09-2019)“…Bisphenol A (BPA) is an endocrine disruptor. To evaluate the effect of canned food consumption on internal BPA dose, urinary BPA concentrations were measured…”
Get full text
Journal Article -
11
Inhibition of the formation of autophagosome but not autolysosome augments ABT‐751‐induced apoptosis in TP53‐deficient Hep‐3B cells
Published in Journal of cellular physiology (01-06-2019)“…Abstarct The objective was to investigate the upstream mechanisms of apoptosis which were triggered by a novel antimicrotubule drug, ABT‐751, in a tumor…”
Get full text
Journal Article -
12
Therapeutic Targeting of Aristolochic Acid Induced Uremic Toxin Retention, SMAD 2/3 and JNK/ERK Pathways in Tubulointerstitial Fibrosis: Nephroprotective Role of Propolis in Chronic Kidney Disease
Published in Toxins (02-06-2020)“…The nephrotoxicity of aristolochic acids (AAs), p-cresyl sulfate (PCS) and indoxyl sulfate (IS) were well-documented, culminating in tubulointerstitial…”
Get full text
Journal Article -
13
Shotgun proteomic analysis using human serum from type 2 diabetes mellitus patients
Published in International journal of diabetes in developing countries (01-02-2023)“…Background Type 2 diabetes mellitus (T2DM), also known as adult-onset diabetes or noninsulin-dependent diabetes mellitus, is characterized by hyperglycemia and…”
Get full text
Journal Article -
14
Synbiotics Alleviate the Gut Indole Load and Dysbiosis in Chronic Kidney Disease
Published in Cells (Basel, Switzerland) (09-01-2021)“…Chronic kidney disease (CKD) has long been known to cause significant digestive tract pathology. Of note, indoxyl sulfate is a gut microbe-derived uremic toxin…”
Get full text
Journal Article -
15
The Long-Term DEHP Exposure Confers Multidrug Resistance of Triple-Negative Breast Cancer Cells through ABC Transporters and Intracellular ROS
Published in Antioxidants (11-06-2021)“…The characteristics of phthalates had been thought to be similar to endocrine disruptors, which increases cancer risk. The role of phthalates in acquired drug…”
Get full text
Journal Article -
16
Ractopamine at the Center of Decades-Long Scientific and Legal Disputes: A Lesson on Benefits, Safety Issues, and Conflicts
Published in Biomolecules (Basel, Switzerland) (21-09-2022)“…Ractopamine (RAC) is a synthetic phenethanolamine, β–adrenergic agonist used as a feed additive to develop leanness and increase feed conversion efficiency in…”
Get full text
Journal Article -
17
Breast cancer is associated with methylation and expression of the a disintegrin and metalloproteinase domain 33 (ADAM33) gene affected by endocrine‑disrupting chemicals
Published in Oncology reports (01-11-2018)“…A disintegrin and metalloproteinase domain 33 (ADAM33) gene is a transmembrane glycoprotein that mediates changes in cell adhesion and plays an important role…”
Get full text
Journal Article -
18
The Impact of Di(2-ethylhexyl)phthalate on Cancer Progression
Published in Archivum Immunologiae et Therapiae Experimentalis (01-06-2018)“…Di(2-ethylhexyl)phthalate (DEHP), a widely used plasticizer, mainly serves as an additive to render polyvinyl chloride (PVC) soft and flexible. PVC plastics…”
Get full text
Journal Article -
19
Protein-bounded uremic toxin p-cresylsulfate induces vascular permeability alternations
Published in Histochemistry and cell biology (01-06-2018)“…The goal of the present studies is to investigate that the impact of p -cresylsulfate (PCS) on the endothelial barrier integrity via in situ exposure and…”
Get full text
Journal Article -
20
Nonapnea Sleep Disorders in Patients Younger than 65 Years Are Significantly Associated with CKD: A Nationwide Population-Based Study
Published in PloS one (14-10-2015)“…Nonapnea sleep disorders (NASD) and sleep-related problems are associated with poor health outcomes. However, the association between NASD and the development…”
Get full text
Journal Article