Search Results - "Liang, Lujun"

Met1-specific motifs conserved in OTUB subfamily of green plants enable rice OTUB1 to hydrolyse Met1 ubiquitin chains by Lu, Lining, Zhai, Xiaoguo, Li, Xiaolong, Wang, Shuansuo, Zhang, Lijun, Wang, Luyang, Jin, Xi, Liang, Lujun, Deng, Zhiheng, Li, Zichen, Wang, Yanfeng, Fu, Xiangdong, Hu, Honggang, Wang, Jiawei, Mei, Ziqing, He, Zhengguo, Wang, Feng

“…Linear (Met1-linked) ubiquitination is involved inflammatory and innate immune signaling. Previous studies have characterized enzymes regulating the addition…”
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Structural insights into Ubr1-mediated N-degron polyubiquitination by Pan, Man, Zheng, Qingyun, Wang, Tian, Liang, Lujun, Mao, Junxiong, Zuo, Chong, Ding, Ruichao, Ai, Huasong, Xie, Yuan, Si, Dong, Yu, Yuanyuan, Liu, Lei, Zhao, Minglei

“…The N-degron pathway targets proteins that bear a destabilizing residue at the N terminus for proteasome-dependent degradation 1 . In yeast, Ubr1—a…”
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H2B Lys34 Ubiquitination Induces Nucleosome Distortion to Stimulate Dot1L Activity by Ai, Huasong, Sun, Maoshen, Liu, Aijun, Sun, Zixian, Liu, Tingting, Cao, Lin, Liang, Lujun, Qu, Qian, Li, Zichen, Deng, Zhiheng, Tong, Zebin, Chu, Guochao, Tian, Xiaolin, Deng, Haiteng, Zhao, Suwen, Li, Jia-Bin, Lou, Zhiyong, Liu, Lei

“…Ubiquitination-dependent histone crosstalk plays critical roles in chromatin-associated processes and is highly associated with human diseases. Mechanism…”
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Chemical Protein Synthesis Enabled Mechanistic Studies on the Molecular Recognition of K27‐linked Ubiquitin Chains by Pan, Man, Zheng, Qingyun, Ding, Shan, Zhang, Lujia, Qu, Qian, Wang, Tian, Hong, Danning, Ren, Yujing, Liang, Lujun, Chen, Chunlai, Mei, Ziqing, Liu, Lei

“…New synthetic strategies that exploited the strengths of both chemoselective ligation and recombinant protein expression were developed to prepare K27…”
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A bifunctional molecule-assisted synthesis of mimics for use in probing the ubiquitination system by Zheng, Qingyun, Wang, Tian, Mao, Junxiong, Chu, Guochao, Liang, Lujun, Jing, Yangwode, Zuo, Chong, Yu, Yuanyuan, Hu, Honggang, Pan, Man

“…Ubiquitination regulates almost every life process of eukaryotes. The study of the ubiquitin (Ub) coupling or decoupling process and the interaction study of…”
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Expedient Synthesis of Ubiquitin‐like Protein ISG15 Tools through Chemo‐Enzymatic Ligation Catalyzed by a Viral Protease Lbpro by Wang, Tian, Li, Chuntong, Wang, Meijing, Zhang, Jiachen, Zheng, Qingyun, Liang, Lujun, Chu, Guochao, Tian, Xiaolin, Deng, Haiteng, He, Wei, Liu, Lei, Li, Jinghong

“…Ubiquitin (Ub)‐like protein ISG15 (interferon‐stimulated gene 15) regulates innate immunity and links with the evasion of host response by viruses such as…”
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Synovial sarcoma X breakpoint 1 protein uses a cryptic groove to selectively recognize H2AK119Ub nucleosomes by Tong, Zebin, Ai, Huasong, Xu, Ziyu, He, Kezhang, Chu, Guo-Chao, Shi, Qiang, Deng, Zhiheng, Xue, Qiaomei, Sun, Maoshen, Du, Yunxiang, Liang, Lujun, Li, Jia-Bin, Pan, Man, Liu, Lei

“…The cancer-specific fusion oncoprotein SS18–SSX1 disturbs chromatin accessibility by hijacking the BAF complex from the promoters and enhancers to the…”
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Simultaneous capture of ISG15 conjugating and deconjugating enzymes using a semi-synthetic ISG15-Dha probe by Li, Chuntong, Wang, Tian, Liang, Lujun, Chu, Guochao, Zhang, Jiachen, He, Wei, Liu, Lei, Li, Jinghong

“…ISG15 is a ubiquitin-like (Ubl) protein attached to substrate proteins by ISG15 conjugating enzymes whose dysregulation is implicated in a multitude of disease…”
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Mechanism of nucleosomal H2A K13/15 monoubiquitination and adjacent dual monoubiquitination by RNF168 by Ai, Huasong, Tong, Zebin, Deng, Zhiheng, Shi, Qiang, Tao, Shixian, Sun, Gaoge, Liang, Jiawei, Sun, Maoshen, Wu, Xiangwei, Zheng, Qingyun, Liang, Lujun, Yin, Hang, Li, Jia-Bin, Gao, Shuai, Tian, Changlin, Liu, Lei, Pan, Man

“…The DNA damage repair regulatory protein RNF168, a monomeric RING-type E3 ligase, has a crucial role in regulating cell fate and DNA repair by specific and…”
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Expedient Synthesis of Ubiquitin‐like Protein ISG15 Tools through Chemo‐Enzymatic Ligation Catalyzed by a Viral Protease Lb pro by Wang, Tian, Li, Chuntong, Wang, Meijing, Zhang, Jiachen, Zheng, Qingyun, Liang, Lujun, Chu, Guochao, Tian, Xiaolin, Deng, Haiteng, He, Wei, Liu, Lei, Li, Jinghong

“…Abstract Ubiquitin (Ub)‐like protein ISG15 (interferon‐stimulated gene 15) regulates innate immunity and links with the evasion of host response by viruses…”
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Simulation study of a thin membrane inclined automatic wicking dew-point evaporative cooling device by Zhou, Bo, Lv, Jing, Zhu, Mengya, Wang, Lihui, Liang, Lujun, Chen, Qinqin

“…In this study, the performance of a novel dew-point evaporative cooling device based on the M-cycle was numerically evaluated. Numerical models of the device…”
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Inactivity of YGL082W in vitro due to impairment of conformational change in the catalytic center loop by Lu, Lining, Guo, Yu, Wang, Tian, Liang, Lujun, Zhao, Suwen, Wang, Feng, Liu, Lei

“…MINDY-1 is a recently discovered new family of deubiquitinating enzymes (DUB), but one of its yeast homologs, YGL082W, does not show any DUB activity in vitro…”
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Semi-synthesis of disulfide-linked branched tri-ubiquitin mimics by Si, Yanyan, Liang, Lujun, Tang, Shan, Qi, Yunkun, Huang, Yong, Liu, Lei

“…Ubiquitin (Ub) chain isopeptide bond mimics are useful molecules for biochemical and biophysical studies. Herein, we report the semi-synthesis of the…”
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Expedient Synthesis of Ubiquitin‐like Protein ISG15 Tools through Chemo‐Enzymatic Ligation Catalyzed by a Viral Protease Lb pro by Wang, Tian, Li, Chuntong, Wang, Meijing, Zhang, Jiachen, Zheng, Qingyun, Liang, Lujun, Chu, Guochao, Tian, Xiaolin, Deng, Haiteng, He, Wei, Liu, Lei, Li, Jinghong

“…Abstract Ubiquitin (Ub)‐like protein ISG15 (interferon‐stimulated gene 15) regulates innate immunity and links with the evasion of host response by viruses…”
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Expedient Synthesis of Ubiquitin‐like Protein ISG15 Tools through Chemo‐Enzymatic Ligation Catalyzed by a Viral Protease Lbpro by Wang, Tian, Li, Chuntong, Wang, Meijing, Zhang, Jiachen, Zheng, Qingyun, Liang, Lujun, Chu, Guochao, Tian, Xiaolin, Deng, Haiteng, He, Wei, Liu, Lei, Li, Jinghong

“…Ubiquitin (Ub)‐like protein ISG15 (interferon‐stimulated gene 15) regulates innate immunity and links with the evasion of host response by viruses such as…”
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Chemical Protein Synthesis Enabled Mechanistic Studies on the Molecular Recognition of K27‐linked Ubiquitin Chains by Pan, Man, Zheng, Qingyun, Ding, Shan, Zhang, Lujia, Qu, Qian, Wang, Tian, Hong, Danning, Ren, Yujing, Liang, Lujun, Chen, Chunlai, Mei, Ziqing, Liu, Lei

“…New synthetic strategies that exploited the strengths of both chemoselective ligation and recombinant protein expression were developed to prepare K27…”
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