Search Results - "Liang, Kaini"

Mesenchymal Stem Cells (MSCs): A Novel Therapy for Type 2 Diabetes by Gao, Shuang, Zhang, Yuanyuan, Liang, Kaini, Bi, Ran, Du, Yanan

“…Although plenty of drugs are currently available for type 2 diabetes mellitus (T2DM), a subset of patients still failed to restore normoglycemia. Recent…”
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Cell mediated ECM-degradation as an emerging tool for anti-fibrotic strategy by Zhao, Peng, Sun, Tian, Lyu, Cheng, Liang, Kaini, Du, Yanan

“…Investigation into the role of cells with respect to extracellular matrix (ECM) remodeling is still in its infancy. Particularly, ECM degradation is an…”
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Cell engineering techniques improve pharmacology of cellular therapeutics by Liang, Kaini, Du, Yanan

“…•Pharmacokinetics (PK) and pharmacodynamics (PD) of cellular therapeutics are intimately associated with the cell viability, homing/retention, interactions,…”
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In situ self-assembled organoid for osteochondral tissue regeneration with dual functional units by Yang, Zhen, Wang, Bin, Liu, Wei, Li, Xiaoke, Liang, Kaini, Fan, Zejun, Li, Jiao Jiao, Niu, Yudi, He, Zihao, Li, Hui, Wang, Du, Lin, Jianjing, Du, Yanan, Lin, Jianhao, Xing, Dan

“…The regeneration of hierarchical osteochondral units is challenging due to difficulties in inducing spatial, directional and controllable differentiation of…”
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Viscoelasticity of ECM and cells—origin, measurement and correlation by Liu, Zhiqiang, Ling, Si Da, Liang, Kaini, Chen, Yihan, Niu, Yudi, Sun, Lei, Li, Junyang, Du, Yanan

“…The extracellular matrix (ECM) and cells are crucial components of natural tissue microenvironments, and they both demonstrate dynamic mechanical properties,…”
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Research hotspots and trends of mesenchymal stem cell-derived extracellular vesicles for drug delivery: a bibliometric and visualization analysis from 2013 to 2023 by Zhao, Tianyuan, Mu, Yuhao, Deng, Haobin, Liang, Kaini, Zhou, Fanfan, Lin, Qiyuan, Cao, Fuyang, Zhou, Feifei, Yang, Zhen

“…Introduction Our study aims to provide a comprehensive overview of mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) in drug delivery research,…”
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Scar‐Degrading Endothelial Cells as a Treatment for Advanced Liver Fibrosis by Zhao, Peng, Sun, Tian, Lyu, Cheng, Liang, Kaini, Niu, Yudi, Zhang, Yuying, Cao, Chenhui, Xiang, Canhong, Du, Yanan

“…Deposition of extracellular matrix (ECM) in the liver is an important feature of liver cirrhosis. Recovery from liver cirrhosis is physiologically challenging,…”
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Injectable bone marrow microniches by co-culture of HSPCs with MSCs in 3D microscaffolds promote hematopoietic reconstitution from acute lethal radiation by Liang, Haiwei, Ao, Yanxiao, Li, Wenjing, Liang, Kaini, Tang, Baixue, Li, Junyang, Wang, Jianwei, Zhu, Xiaoyu, Du, Yanan

“…Hematopoietic syndrome of acute radiation syndrome (h-ARS) is an acute illness resulted from the damage of bone marrow (BM) microenvironment after exposure to…”
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Enhanced bone regeneration via endochondral ossification using Exendin-4-modified mesenchymal stem cells by He, Zihao, Li, Hui, Zhang, Yuanyuan, Gao, Shuang, Liang, Kaini, Su, Yiqi, Wang, Du, Yang, Zhen, Du, Yanan, Xing, Dan, Lin, Jianhao

“…Nonunions and delayed unions pose significant challenges in orthopedic treatment, with current therapies often proving inadequate. Bone tissue engineering…”
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Mechanical communication in fibrosis progression by Long, Yi, Niu, Yudi, Liang, Kaini, Du, Yanan

“…Mechanical hallmarks of fibrotic microenvironments are both outcomes and causes of fibrosis progression. Understanding how cells sense and transmit mechanical…”
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Engineered meatballs via scalable skeletal muscle cell expansion and modular micro-tissue assembly using porous gelatin micro-carriers by Liu, Ye, Wang, Rui, Ding, Shijie, Deng, Liping, Zhang, Yuanyuan, Li, Junyang, Shi, Ziao, Wu, Zhongyuan, Liang, Kaini, Yan, Xiaojun, Liu, Wei, Du, Yanan

“…The emerging field of cultured meat faces several technical hurdles, including the scale-up production of quality muscle and adipose progenitor cells, and the…”
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Gelatin-based 3D biomimetic scaffolds platform potentiates culture of cancer stem cells in esophageal squamous cell carcinoma by Wu, Yenan, Liang, Haiwei, Luo, Aiping, Li, Yong, Liu, Zhiqiang, Li, Xin, Li, Wenxin, Liang, Kaini, Li, Junyang, Liu, Zhihua, Du, Yanan

“…Cancer stem cells (CSCs) are crucial for tumorigenesis, metastasis, and therapy resistance in esophageal squamous cell carcinoma (ESCC). To further elucidate…”
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Water Transport‐Induced Liquid–Liquid Phase Separation Facilitates Gelation for Controllable and Facile Fabrication of Physically Crosslinked Microgels by Chen, Michael W, Fan, Dongdong, Liu, Xiangjian, Han, Dongbo, Jin, Yuhong, Ao, Yanxiao, Chen, Yuyang, Liu, Zhiqiang, Feng, Yiting, Ling, Sida, Liang, Kaini, Kong, Wenyu, Xu, Jianhong, Du, Yanan

“…Physically crosslinked microgels (PCMs) offer a biocompatible platform for various biomedical applications. However, current PCM fabrication methods suffer…”
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Precise cell therapy for liver fibrosis: Endothelial cell and macrophage therapy by Deng, Liping, Wu, Bingjie, Liang, Kaini, Liao, Hongen, Du, Yanan

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Advanced glycation end-products as mediators of the aberrant crosslinking of extracellular matrix in scarred liver tissue by Lyu, Cheng, Kong, Wenyu, Liu, Zhiqiang, Wang, Sihan, Zhao, Peng, Liang, Kaini, Niu, Yudi, Yang, Wei, Xiang, Canhong, Hu, Xiaoyu, Li, Xueming, Du, Yanan

“…The extracellular matrix of cirrhotic liver tissue is highly crosslinked. Here we show that advanced glycation end-products (AGEs) mediate crosslinking in…”
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Exendin-4 gene modification and microscaffold encapsulation promote self-persistence and antidiabetic activity of MSCs by Zhang, Yuanyuan, Gao, Shuang, Liang, Kaini, Wu, Zhaozhao, Yan, Xiaojun, Liu, Wei, Li, Junyang, Wu, Bingjie, Du, Yanan

“…Mesenchymal stem cell (MSC)-based therapy to combat diabetic-associated metabolic disorders is hindered by impoverished cell survival and limited therapeutic…”
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Superimposed Electric Field Enhanced Electrospray for High-Throughput and Consistent Cell Encapsulation by Fan, Zejun, Chen, Yihan, Yang, Zhen, Niu, Yudi, Liang, Kaini, Zhang, Yan, Zeng, Jianan, Feng, Yiting, Zhang, Yuying, Liu, Ye, Lv, Cheng, Zhao, Peng, Zhou, Lv, Kong, Wenyu, Li, Wenjing, Chen, Haoke, Han, Dongbo, Du, Yanan

“…Cell encapsulation technology, crucial for advanced biomedical applications, faces challenges in existing microfluidic and electrospray methods. Microfluidic…”
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