Search Results - "Liana Melo-Thomas"
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Low frequency deep brain stimulation in the inferior colliculus ameliorates haloperidol-induced catalepsy and reduces anxiety in rats
Published in PloS one (04-12-2020)“…Deep brain stimulation (DBS) of the colliculus inferior (IC) improves haloperidol-induced catalepsy and induces paradoxal kinesia in rats. Since the IC is part…”
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Clozapine prevented social interaction deficits and reduced c-Fos immunoreactivity expression in several brain areas of rats exposed to acute restraint stress
Published in PloS one (03-03-2022)“…In the present study, we evaluate the effect of acute restraint stress (15 min) of male Wistar rats on social interaction measurements and c-Fos…”
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3
Paradoxical Kinesia Induced by Nightmare: Unique Case Report and Insights regarding the Neural Mechanism Based on Human and Rat Studies
Published in Case reports in neurology (30-05-2024)“…Bradykinesia, characterized by slowed movement, stands out as a primary symptom observed in individuals with Parkinson's disease (PD). Nonetheless, there are…”
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OPTOGENETIC STIMULATION OF THE INFERIOR COLLICULUS ACTIVATES NEURONS IN THE MESENCEPHALIC LOCOMOTOR REGION AND INDUCES PARADOXICAL KINESIA
Published in IBRO neuroscience reports (01-10-2023)Get full text
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Deep brain stimulation of the inferior colliculus: A possible animal model to study paradoxical kinesia observed in some parkinsonian patients?
Published in Behavioural brain research (15-02-2015)“…The inferior colliculus (IC) plays an important role in the normal processing of the acoustic message and is also involved in the filtering of acoustic stimuli…”
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Nitric oxide-signalling affects panic-like defensive behaviour and defensive antinociception neuromodulation in the prelimbic cerebral cortex
Published in Brain research (01-12-2024)“…Effect of microinjection of either NPLA (NOS inhibitor) or c-PTIO (NO scavenger) in the prelimbic division (PrL) of the medial prefrontal cortex (mPFC),…”
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Awakenings in rats by ultrasounds: A new animal model for paradoxical kinesia
Published in Behavioural brain research (30-01-2018)“…Paradoxical kinesia refers to a sudden transient ability of akinetic patients to perform motor tasks they are otherwise unable to perform. The mechanisms…”
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Paradoxical kinesia induced by appetitive 50-kHz ultrasonic vocalizations in rats depends on glutamatergic mechanisms in the inferior colliculus
Published in Neuropharmacology (01-06-2018)“…Paradoxical kinesia is a sudden transient ability of akinetic patients to perform motor tasks they are otherwise unable to perform. This phenomenon is known to…”
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Playback of 50-kHz ultrasonic vocalizations overcomes psychomotor deficits induced by sub-chronic haloperidol treatment in rats
Published in Psychopharmacology (01-07-2020)“…Rationale In rodents, acute haloperidol treatment induces psychomotor impairments known as catalepsy, which models akinesia in humans and is characterized as…”
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Haloperidol–induced catalepsy is ameliorated by deep brain stimulation of the inferior colliculus
Published in Scientific reports (02-02-2018)“…Deep brain stimulation (DBS) has evolved as a promising alternative treatment for Parkinson’s disease (PD), but the underlying mechanisms remain poorly…”
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Stress-induced endocrine response and anxiety: the effects of comfort food in rats
Published in Stress (Amsterdam, Netherlands) (01-05-2014)“…The long-term effects of comfort food in an anxiogenic model of stress have yet to be analyzed. Here, we evaluated behavioral, endocrine and metabolic…”
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Lateralization in hemi-parkinsonian rats is affected by deep brain stimulation or glutamatergic neurotransmission in the inferior colliculus
Published in eNeuro (11-07-2022)“…After unilateral lesion of the medial forebrain bundle (MFB) by 6-OHDA rats exhibit lateralized deficits in spontaneous behavior or apomorphine-induced…”
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Deep brain stimulation of the dorsal raphe inhibits avoidance and escape reactions and activates forebrain regions related to the modulation of anxiety/panic
Published in Behavioural brain research (15-03-2017)“…•DBS applied to the DRD is anxiolytic.•DRB applied to the lwDR is panicolytic.•DBS applied to the DRD increases Fos-ir in forebrain anxiety-related regions…”
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Lateralization in Hemiparkinsonian Rats Is Affected by either Deep Brain Stimulation or Glutamatergic Neurotransmission in the Inferior Colliculus
Published in eNeuro (01-07-2022)“…After unilateral lesion of the medial forebrain bundle by 6-OHDA rats exhibit lateralized deficits in spontaneous behavior or apomorphine-induced rotations. We…”
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15
Atypical antipsychotic olanzapine reversed deficit on prepulse inhibition of the acoustic startle reflex produced by microinjection of dizocilpine (MK-801) into the inferior colliculus in rats
Published in Behavioural brain research (15-11-2013)“…•Unilateral microinjections of MK-801, an NMDA antagonist, into the inferior colliculus (IC) disrupted PPI.•Microinjections of NMDA into the IC did not alter…”
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A Wireless, Bidirectional Interface for In Vivo Recording and Stimulation of Neural Activity in Freely Behaving Rats
Published in Journal of visualized experiments (07-11-2017)“…In vivo electrophysiology is a powerful technique to investigate the relationship between brain activity and behavior at a millisecond and micrometer scale…”
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Unpredictable chronic mild stress exerts anxiogenic-like effects and activates neurons in the dorsal and caudal region and in the lateral wings of the dorsal raphe nucleus
Published in Behavioural brain research (15-01-2016)“…•Unpredictable chronic mild stress is anxiogenic.•Chronic stress increases Fos immunoreactivity in the caudal dorsal raphe.•Chronic stress activates…”
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A Wireless, Bidirectional Interface for In Vivo Recording and Stimulation of Neural Activity in Freely Behaving Rats
Published in Journal of visualized experiments (07-11-2017)Get full text
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19
Clozapine prevented social interaction deficits and reduced c-Fos immunoreactivity expression in several brain areas of rats exposed to acute restraint stress
Published in PloS one (01-01-2022)“…In the present study, we evaluate the effect of acute restraint stress (15 min) of male Wistar rats on social interaction measurements and c-Fos…”
Get full text
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