Search Results - "Lian, Zhexiong"

The microbiota maintain homeostasis of liver-resident γδT-17 cells in a lipid antigen/CD1d-dependent manner by Li, Fenglei, Hao, Xiaolei, Chen, Yongyan, Bai, Li, Gao, Xiang, Lian, Zhexiong, Wei, Haiming, Sun, Rui, Tian, Zhigang

“…The microbiota control regional immunity using mechanisms such as inducing IL-17A-producing γδ T (γδT-17) cells in various tissues. However, little is known…”
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TRIM30α Is a Negative-Feedback Regulator of the Intracellular DNA and DNA Virus-Triggered Response by Targeting STING by Wang, Yanming, Lian, Qiaoshi, Yang, Bo, Yan, Shanshan, Zhou, Haiyan, He, Lan, Lin, Guomei, Lian, Zhexiong, Jiang, Zhengfan, Sun, Bing

“…Uncontrolled immune responses to intracellular DNA have been shown to induce autoimmune diseases. Homeostasis regulation of immune responses to cytosolic DNA…”
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Memory formation and long-term maintenance of IL-7Rα+ ILC1s via a lymph node-liver axis by Wang, Xianwei, Peng, Hui, Cong, Jingjing, Wang, Xuefu, Lian, Zhexiong, Wei, Haiming, Sun, Rui, Tian, Zhigang

“…Natural killer (NK) cells are reported to have immunological memory, with CD49a + liver-resident NK cells shown to confer hapten-specific memory responses, but…”
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Two populations of self-maintaining monocyte-independent macrophages exist in adult epididymis and testis by Wang, Ming, Yang, Yalong, Cansever, Dilay, Wang, Yiming, Kantores, Crystal, Messiaen, Sébastien, Moison, Delphine, Livera, Gabriel, Chakarov, Svetoslav, Weinberger, Tobias, Stremmel, Christopher, Fijak, Monika, Klein, Britta, Pleuger, Christiane, Lian, Zhexiong, Ma, Wentao, Liu, Qingzhi, Klee, Kathrin, Händler, Kristian, Ulas, Thomas, Schlitzer, Andreas, Schultze, Joachim L., Becher, Burkhard, Greter, Melanie, Liu, Zhaoyuan, Ginhoux, Florent, Epelman, Slava, Schulz, Christian, Meinhardt, Andreas, Bhushan, Sudhanshu

“…Macrophages are the principal immune cells of the epididymis and testis, but their origins, heterogeneity, development, and maintenance are not well…”
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HBV immune tolerance of HBs-transgenic mice observed through parabiosis with WT mice by Zhang, Wendi, Sun, Haoyu, Sun, Rui, Lian, Zhexiong, Wei, Haiming, Tian, Zhigang, Chen, Yongyan

“…It was extensively recognized that central tolerance to HBV exists in HBs-transgenic (Tg) mice, however, the immune response to HBV vaccine may be inspired in…”
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Author Correction: Memory formation and long-term maintenance of IL-7Rα+ ILC1s via a lymph node-liver axis by Wang, Xianwei, Peng, Hui, Cong, Jingjing, Wang, Xuefu, Lian, Zhexiong, Wei, Haiming, Sun, Rui, Tian, Zhigang

“…The original version of this Article contained errors in Figs. 1 and 6. In Fig. 1c, the label ‘CD49a + IL-7Rα + ILC1’ incorrectly read ‘CD49a + IL-7Rα − ILC1’…”
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XBP1-mediated activation of the STING signalling pathway in macrophages contributes to liver fibrosis progression by Wang, Qi, Bu, Qingfa, Liu, Mu, Zhang, Rui, Gu, Jian, Li, Lei, Zhou, Jinren, Liang, Yuan, Su, Wantong, Liu, Zheng, Wang, Mingming, Lian, Zhexiong, Lu, Ling, Zhou, Haoming

“…XBP1 modulates the macrophage proinflammatory response, but its function in macrophage stimulator of interferon genes (STING) activation and liver fibrosis is…”
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Interleukin-35 Promotes Th9 Cell Differentiation in IgG4-Related Disorders: Experimental Data and Review of the Literature by Zhang, Jun, Lian, Min, Li, Bo, Gao, Lixia, Tanaka, Toshihiro, You, Zhengrui, Wei, Yiran, Chen, Yong, Li, Yikang, Li, You, Huang, Bingyuan, Tang, Ruqi, Wang, Qixia, Miao, Qi, Peng, Yanshen, Fang, Jingyuan, Lian, Zhexiong, Okazaki, Kazuichi, Xiao, Xiao, Zhang, Weici, Ma, Xiong

“…IgG4-related disease (IgG4-RD) is characterized by intense infiltration of IgG4-positive plasma cells in affected organs. However, the mechanisms acting in the…”
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Erratum: The microbiota maintain homeostasis of liver-resident γδT-17 cells in a lipid antigen/CD1d-dependent manner by Li, Fenglei, Hao, Xiaolei, Chen, Yongyan, Bai, Li, Gao, Xiang, Lian, Zhexiong, Wei, Haiming, Sun, Rui, Tian, Zhigang

“…Nature Communications 8 Article number:13839 (2017); Published 9 January 2017; Updated 10 April 2017 The HTML version of this Article previously published had…”
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The differential organogenesis and functionality of two liver-draining lymph nodes in mice by Yu, Jiali, Chen, Yongyan, Wu, Yuzhang, Ye, Lilin, Lian, Zhexiong, Wei, Haiming, Sun, Rui, Tian, Zhigang

“…The liver is an immunological organ. However, fundamental knowledge concerning liver-draining lymph nodes (LNs), which have been newly identified in mice as…”
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Dynamic single-cell mapping unveils Epstein‒Barr virus-imprinted T-cell exhaustion and on-treatment response by Qiu, Miao-Zhen, Wang, Chaoye, Wu, Zhiying, Zhao, Qi, Zhao, Zhibin, Huang, Chun-Yu, Wu, Wenwei, Yang, Li-Qiong, Zhou, Zhi-Wei, Zheng, Yu, Pan, Hong-Ming, Liu, Zexian, Zeng, Zhao-Lei, Luo, Hui-Yan, Wang, Feng, Wang, Feng-Hua, Yang, Si-Yu, Huang, Meng-Xing, Lian, Zhexiong, Zhang, Haiyan, Xu, Rui-Hua

“…Epstein‒Barr virus (EBV)-associated gastric cancer (GC) manifests an intriguing immunotherapy response. However, the cellular basis for EBV-imprinted tumour…”
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Experimental evidence on the immunopathogenesis of primary biliary cirrhosis by Selmi, Carlo, Meda, Francesca, Kasangian, Anaid, Invernizzi, Pietro, Tian, Zhigang, Lian, Zhexiong, Podda, Mauro, Gershwin, M Eric

“…Primary biliary cirrhosis (PBC) is a chronic cholestatic liver disease for which an autoimmune pathogenesis is supported by clinical and experimental data,…”
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Combination of intra-bone marrow-bone marrow transplantation and subcutaneous donor splenocyte injection diminishes risk of graft-versus-host disease and enhances survival rate by Shi, Ming, Adachi, Yasushi, Cui, Yunze, Li, Ming, Lian, Zhexiong, Zhang, Yuming, Yanai, Seiji, Shima, Chieko, Imai, Yuichiro, Ikehara, Susumu

“…The combination of allogeneic bone marrow transplantation (allo-BMT) and donor lymphocyte infusion (DLI) is a useful method for establishing donor chimerism…”
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Characterization of Mesenchymal Stem Cells Isolated from Mouse Fetal Bone Marrow by Wang, Xiaoli, Hisha, Hiroko, Taketani, Shigeru, Adachi, Yasushi, Li, Qiang, Cui, Wenhao, Cui, Yunze, Wang, Jianfeng, Song, Changye, Mizokami, Tomomi, Okazaki, Satoshi, Li, Qing, Fan, Tianxue, Fan, Hongxue, Lian, Zhexiong, Gershwin, M. Eric, Ikehara, Susumu

“…Mesenchymal stem cells (MSCs) are defined as cells that can differentiate into multiple mesenchymal lineage cells. MSCs have some features (surface molecules…”
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Intracellular coassembly boosts the anti-inflammation capacity of dexamethasone by Tang, Wei, Yang, Jingbo, Zhao, Zhibin, Lian, Zhexiong, Liang, Gaolin

“…Dexamethasone (Dex) is one of the essential medicines used to treat inflammation diseases but an overdose of Dex leads to severe adverse effects. The…”
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Kupffer Cells Support Hepatitis B Virus-Mediated CD8+ T Cell Exhaustion via Hepatitis B Core Antigen-TLR2 Interactions in Mice by Li, Min, Sun, Rui, Xu, Long, Yin, Wenwei, Chen, Yongyan, Zheng, Xiaodong, Lian, Zhexiong, Wei, Haiming, Tian, Zhigang

“…Hepatitis B virus (HBV) persistence is a fundamental process in chronic HBV infection and a key factor in all related liver diseases; however, the mechanisms…”
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Invariant NKT cells promote alcohol-induced steatohepatitis through interleukin-1β in mice by Cui, Kele, Yan, Guoxiu, Xu, Congfei, Chen, Yongyan, Wang, Jun, Zhou, Rongbin, Bai, Li, Lian, Zhexiong, Wei, Haiming, Sun, Rui, Tian, Zhigang

“…Graphical abstract…”
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Oral ampicillin inhibits liver regeneration by breaking hepatic innate immune tolerance normally maintained by gut commensal bacteria by Wu, Xunyao, Sun, Rui, Chen, Yongyan, Zheng, Xiaodong, Bai, Li, Lian, Zhexiong, Wei, Haiming, Tian, Zhigang

“…Commensal bacteria have been proposed to play a role in liver repair after partial (67%) hepatectomy. However, the underlying immune mechanisms remain elusive…”
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Paclitaxel nanoparticle awakens immune system to fight against cancer by Tang, Wei, Yang, Jingbo, Yuan, Yue, Zhao, Zhibin, Lian, Zhexiong, Liang, Gaolin

“…A high concentration of paclitaxel (PTX) is used as an anti-tumor chemotherapy but is toxic to immune cells. At lower concentrations, PTX was found able to…”
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The AKR1C1-CYP1B1-cAMP signaling axis controls tumorigenicity and ferroptosis susceptibility of extrahepatic cholangiocarcinoma by Liu, Chang, Zhang, Cheng, Wu, Hongkun, Zhao, Zhibin, Wang, Zhenhua, Zhang, Xiaomin, Yang, Jieli, Yu, Wenlong, Lian, Zhexiong, Gao, Minghui, Zhou, Lin

“…Extrahepatic cholangiocarcinoma (ECC), a highly malignant type of cancer with increasing incidence, has a poor prognosis due to limited treatment options…”
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