Search Results - "Lian, Wen"
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Glucose metabolism in gastric cancer: The cutting-edge
Published in World journal of gastroenterology : WJG (14-02-2016)“…Glucose metabolism in gastric cancer cells differsfrom that of normal epithelial cells. Upregulatedaerobic glycolysis (Warburg effect) in gastric cancermeeting…”
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Hydrogen-bond structure dynamics in bulk water: insights from ab initio simulations with coupled cluster theory
Published in Chemical science (Cambridge) (28-02-2018)“…An accurate and efficient molecular dynamics (AIMD) simulation of liquid water was made possible using the fragment-based approach (J. F. Liu, X. He and J. Z…”
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Ginsenosides from American ginseng: Chemical and pharmacological diversity
Published in Phytochemistry (Oxford) (01-06-2011)“…Ginseng occupies a prominent position in best-selling natural products, and ginsenosides from American ginseng possess diversity in chemical structures and…”
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miRTarBase 2020: updates to the experimentally validated microRNA–target interaction database
Published in Nucleic acids research (08-01-2020)“…Abstract MicroRNAs (miRNAs) are small non-coding RNAs (typically consisting of 18–25 nucleotides) that negatively control expression of target genes at the…”
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Proteomic analysis reveals ginsenoside Rb1 attenuates myocardial ischemia/reperfusion injury through inhibiting ROS production from mitochondrial complex I
Published in Theranostics (2021)“…Reactive oxygen species (ROS) burst from mitochondrial complex I is considered the critical cause of ischemia/reperfusion (I/R) injury. Ginsenoside Rb1 has…”
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6
GSAlign: an efficient sequence alignment tool for intra-species genomes
Published in BMC genomics (24-02-2020)“…Personal genomics and comparative genomics are becoming more important in clinical practice and genome research. Both fields require sequence alignment to…”
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Glucagon up‐regulates hepatic mitochondrial pyruvate carrier 1 through cAMP‐responsive element‐binding protein; inhibition of hepatic gluconeogenesis by ginsenoside Rb1
Published in British journal of pharmacology (01-08-2019)“…Background and Purpose Hepatic mitochondrial pyruvate carrier (MPC) transports pyruvate into mitochondria. This study investigated the involvement of MPC1 in…”
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Comprehensive Metabolomic Characterization of Coronary Artery Diseases
Published in Journal of the American College of Cardiology (20-09-2016)“…Abstract Background Pathogenesis and diagnostic biomarkers for diseases can be discovered by metabolomic profiling of human fluids. If the various types of…”
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Coordinated changes of gut microbiome and lipidome differentiates nonalcoholic steatohepatitis (NASH) from isolated steatosis
Published in Liver international (01-03-2020)“…Background & Aims Nonalcoholic fatty liver disease encompasses isolated steatosis or nonalcoholic fatty liver and nonalcoholic steatohepatitis (NASH). NASH…”
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Electrochemiluminescence bipolar electrode array for the multiplexed detection of glucose, lactate and choline based on a versatile enzymatic approach
Published in Talanta (Oxford) (01-04-2017)“…A simple, efficient and versatile biosensing platform capable of the multiplexed detection for glucose, lactate and choline was developed by the integration of…”
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The role of metformin and resveratrol in the prevention of hypoxia‐inducible factor 1α accumulation and fibrosis in hypoxic adipose tissue
Published in British journal of pharmacology (01-06-2016)“…Background and Purpose Hypoxic activation of hypoxia‐inducible factor 1α (HIF‐1α) and fibrosis in adipose tissue contribute to adipose dysfunction. This study…”
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miRTarBase 2016: updates to the experimentally validated miRNA-target interactions database
Published in Nucleic acids research (04-01-2016)“…MicroRNAs (miRNAs) are small non-coding RNAs of approximately 22 nucleotides, which negatively regulate the gene expression at the post-transcriptional level…”
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13
American ginseng: Potential structure–function relationship in cancer chemoprevention
Published in Biochemical pharmacology (01-10-2010)“…Possible structure–function relationship of ginsenosides against cancer: anticancer activity is inversely correlated to the number of sugars. Sugar linkage…”
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Access to Aminated Saturated Oxygen Heterocycles via Copper-Catalyzed Aminooxygenation of Alkenes
Published in Organic letters (03-03-2017)“…A copper-catalyzed aminooxygenation of unactivated alkenes with various O-nucleophiles is described. This novel methodology uses commercially available…”
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Co-AMPpred for in silico-aided predictions of antimicrobial peptides by integrating composition-based features
Published in BMC bioinformatics (30-07-2021)“…Abstract Background Antimicrobial peptides (AMPs) are oligopeptides that act as crucial components of innate immunity, naturally occur in all multicellular…”
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Phytochemistry, synthesis, analytical methods, pharmacological activity, and pharmacokinetics of loganin: A comprehensive review
Published in Phytotherapy research (01-06-2022)“…Iridoid glycosides (IGs) are found in many medicinal and edible plants, such as Gardenia jasminoides, Cistanche tubulosa, Eucommia ulmoides, Rehmanniae Radix,…”
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Copper‐Catalyzed Remote C−H Amination of Quinolines with N‐Fluorobenzenesulfonimide
Published in Advanced synthesis & catalysis (20-03-2017)“…A copper‐catalyzed remote C−H amination of 8‐aminoquinoline scaffolds on the C5 position is described. The protocol employs commercially available…”
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Hierarchical and programmable one-pot synthesis of oligosaccharides
Published in Nature communications (06-12-2018)“…The programmable one-pot oligosaccharide synthesis method was designed to enable the rapid synthesis of a large number of oligosaccharides, using the software…”
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Sodium oligomannate therapeutically remodels gut microbiota and suppresses gut bacterial amino acids-shaped neuroinflammation to inhibit Alzheimer’s disease progression
Published in Cell research (01-10-2019)“…Recently, increasing evidence has suggested the association between gut dysbiosis and Alzheimer’s disease (AD) progression, yet the role of gut microbiota in…”
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Inactivation of NF-κB2 (p52) restrains hepatic glucagon response via preserving PDE4B induction
Published in Nature communications (20-09-2019)“…Glucagon promotes hepatic gluconeogenesis and maintains whole-body glucose levels during fasting. The regulatory factors that are involved in fasting glucagon…”
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