Search Results - "Lian, Tiong Yee"
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Melatonin Prevents Oxidative Stress-Induced Mitochondrial Dysfunction and Apoptosis in High Glucose-Treated Schwann Cells via Upregulation of Bcl2, NF-κB, mTOR, Wnt Signalling Pathways
Published in Antioxidants (26-06-2019)“…Neuropathy is a complication that affects more than 50% of long-standing diabetic patients. One of the causes of diabetes neuropathy (DN) is the apoptosis of…”
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Edible Bird’s Nest: Recent Updates and Industry Insights Based On Laboratory Findings
Published in Frontiers in pharmacology (01-10-2021)“…Edible bird’s nest (EBN) is a traditional Chinese delicacy made of the saliva of swiftlets found in Southeast Asia. With increasing demands for EBN, quality…”
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Chronic obstructive pulmonary disease: Signs and symptoms, diagnosis, treatments, lifestyle risk factors and management
Published in Life Sciences, Medicine and Biomedicine (Online) (17-03-2024)“…Chronic Obstructive Pulmonary Disease (COPD) is associated with increased health complications, leading to a rise in mortality rates. COPD remains a…”
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4‐chloro‐1,2‐phenylenediamine Induces Apoptosis in Mardin–Darby canine kidney cells via activation of caspases
Published in Environmental toxicology (01-06-2014)“…4‐Chloro‐1,2‐phenylenediamine (4‐Cl‐o‐PD) is a halogenated aromatic diamine that was used as a precursor for manufacturing permanent hair dyes. Despite its…”
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[Zn(phen)(O,N,O)(H2O)] and [Zn(phen)(O,N)(H2O)] with O,N,O is 2,6-dipicolinate and N,O is l-threoninate: synthesis, characterization, and biomedical properties
Published in Journal of biological inorganic chemistry (01-10-2012)“…Two ternary Zn(II) complexes, with 1,10-phenanthroline (phen) as the main ligand and a carboxylate-containing ligand [dipicolinate (dipico) or l -threoninate (…”
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Cytotoxic and apoptogenic effects of Strobilanthes crispa Blume extracts on nasopharyngeal cancer cells
Published in Molecular medicine reports (01-10-2015)“…The chemotherapeutic agents used to treat nasopharyngeal cancer (NPC) exhibit low efficacy. Strobilanthes crispa Blume is widely used for its anticancer,…”
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CCAT 1- A Pivotal Oncogenic Long Non-Coding RNA in Colorectal Cancer
Published in British journal of biomedical science (21-03-2023)“…Colorectal cancer (CRC) is ranked as the third most common cancer and second deadliest cancer in both men and women in the world. Currently, the cure rate and…”
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Melatonin promotes Schwann cell dedifferentiation and proliferation through the Ras/Raf/ERK and MAPK pathways, and glial cell‑derived neurotrophic factor expression
Published in Experimental and therapeutic medicine (01-11-2020)“…Upon peripheral nerve injury (PNI), continuous proliferation of Schwann cells is critical for axon regeneration and tubular reconstruction for nerve…”
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Selective anticancer copper(II)-mixed ligand complexes: targeting of ROS and proteasomes
Published in Metallomics (01-01-2014)“…Copper compounds can be alternatives to platinum-based anticancer drugs. This study investigated the effects of a series of ternary copper(II) complexes,…”
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Melatonin ameliorates high glucose-induced autophagy in Schwann cells
Published in International journal of biochemistry and molecular biology (2023)“…Diabetic neuropathy (DN) is a condition in which nerve fibers are continually exposed to high glucose-induced free radicals. Recent discoveries demonstrated…”
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Apoptosis induced by para‐phenylenediamine involves formation of ROS and activation of p38 and JNK in chang liver cells
Published in Environmental toxicology (01-09-2014)“…para‐phenylenediamine (p‐PD) is a suspected carcinogen, but it has been widely used as a component in permanent hair dyes. In this study, the mechanism of…”
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Anticancer mechanisms of Strobilanthes crispa Blume hexane extract on liver and breast cancer cell lines
Published in Oncology letters (01-10-2017)“…Cancer is a major public health concern not only in developed countries, but also in developing countries. It is one of the leading causes of mortality…”
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Melatonin protects against hyperglycemia-induced Schwann cells apoptosis through MTOR and Wnt signaling pathways
Published in Frontiers in cellular neuroscience (2016)“…Abstract only…”
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Selective anticancer copper(ii)-mixed ligand complexes: targeting of ROS and proteasomesElectronic supplementary information (ESI) available: (i) Morphological observations of MDA-MB-231 and MCF10A cells which are untreated or treated with various concentrations of copper(ii) compounds for 24 h (Fig. S1.1-S1.5A and B); (ii) a comparison between untreated and treated MDA-MB-231 and MCF10A cells in the percentage of apoptosis after incubation with 5 μM copper(ii) complexes for 24 h by flow cytomet
Published 26-03-2014“…Copper compounds can be alternatives to platinum-based anticancer drugs. This study investigated the effects of a series of ternary copper( ii ) complexes,…”
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Anti-neuroinflammatory mechanism of safinamide in inhibiting lipopolysaccharide-induced microglial activation
Published in Pharmaceutical sciences Asia (2023)Get full text
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