Search Results - "Lian, Piaopiao"
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Common mechanisms underlying axonal transport deficits in neurodegenerative diseases: a mini review
Published in Frontiers in molecular neuroscience (24-04-2023)“…Many neurodegenerative diseases including Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis are characterized by the accumulation of…”
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Identification of metabolism-related subtypes and feature genes in Alzheimer’s disease
Published in Journal of translational medicine (15-09-2023)“…Abstract Background Owing to the heterogeneity of Alzheimer's disease (AD), its pathogenic mechanisms are yet to be fully elucidated. Evidence suggests an…”
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Irisin inhibits microglial senescence via TFAM-mediated mitochondrial metabolism in a mouse model of tauopathy
Published in Immunity & ageing (14-05-2024)“…The accumulation of senescent microglia has been highlighted as a critical contributor to the progression of tauopathies. Irisin, a muscle-derived hormone…”
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Identification and experimental validation of m7G-related molecular subtypes, immune signature, and feature genes in Alzheimer's disease
Published in Heliyon (15-07-2024)“…Studies has shown that N7-methylguanosine (m7G) modification plays a critical role in neurological diseases. However, the exact role and association of m7G…”
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ONO-2506 Can Delay Levodopa-induced Dyskinesia in the Early Stage
Published in Neuroscience (15-07-2023)“…[Display omitted] •ONO-2506 can delay the emergence of AIMs after L-DOPA administration.•ONO-2506 can reduce the total AIM score and delay LID…”
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Analysis and experimental validation of necroptosis-related molecular classification, immune signature and feature genes in Alzheimer’s disease
Published in Apoptosis (London) (01-06-2024)“…Necroptosis, a programmed cell death pathway, has been demonstrated to be activated in Alzheimer’s disease (AD). However, the precise role of necroptosis and…”
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AMPK-mediated autophagy pathway activation promotes ΔFosB degradation to improve levodopa-induced dyskinesia
Published in Cellular signalling (01-06-2024)“…Parkinson's disease patients on chronic levodopa often suffer from motor complications, which tend to reduce their quality of life. Levodopa-induced dyskinesia…”
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