Search Results - "Li Puma, D D"

Extracellular Tau Oligomers Produce An Immediate Impairment of LTP and Memory by Fá, M., Puzzo, D., Piacentini, R., Staniszewski, A., Zhang, H., Baltrons, M. A., Li Puma, D. D., Chatterjee, I., Li, J., Saeed, F., Berman, H. L., Ripoli, C., Gulisano, W., Gonzalez, J., Tian, H., Costa, J. A., Lopez, P., Davidowitz, E., Yu, W. H., Haroutunian, V., Brown, L. M., Palmeri, A., Sigurdsson, E. M., Duff, K. E., Teich, A. F., Honig, L. S., Sierks, M., Moe, J. G., D’Adamio, L., Grassi, C., Kanaan, N. M., Fraser, P. E., Arancio, O.

“…Non-fibrillar soluble oligomeric forms of amyloid-β peptide (oAβ) and tau proteins are likely to play a major role in Alzheimer’s disease (AD). The prevailing…”
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Protection of primary neurons and mouse brain from Alzheimer’s pathology by molecular tweezers by Attar, Aida, Ripoli, Cristian, Riccardi, Elisa, Maiti, Panchanan, Li Puma, Domenica D., Liu, Tingyu, Hayes, Jane, Jones, Mychica R., Lichti-Kaiser, Kristin, Yang, Fusheng, Gale, Greg D., Tseng, Chi-hong, Tan, Miao, Xie, Cui-Wei, Straudinger, Jeffrey L., Klärner, Frank-Gerrit, Schrader, Thomas, Frautschy, Sally A., Grassi, Claudio, Bitan, Gal

“…Alzheimer’s disease is a devastating cureless neurodegenerative disorder affecting >35 million people worldwide. The disease is caused by toxic oligomers and…”
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LTP and memory impairment caused by extracellular Aβ and Tau oligomers is APP-dependent by Puzzo, Daniela, Piacentini, Roberto, Fá, Mauro, Gulisano, Walter, Li Puma, Domenica D, Staniszewski, Agnes, Zhang, Hong, Tropea, Maria Rosaria, Cocco, Sara, Palmeri, Agostino, Fraser, Paul, D'Adamio, Luciano, Grassi, Claudio, Arancio, Ottavio

“…The concurrent application of subtoxic doses of soluble oligomeric forms of human amyloid-beta (oAβ) and Tau (oTau) proteins impairs memory and its…”
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HSV-1 infection induces phosphorylated tau propagation among neurons via extracellular vesicles by Protto, V, Miteva, M T, Iannuzzi, F, Marcocci, M E, Li Puma, D D, Piacentini, R, Belli, M, Sansone, L, Pietrantoni, A, Grassi, C, Palamara, A T, De Chiara, G

“…Extracellular vesicles (EV), key players in cell-to-cell communication, may contribute to disease propagation in several neurodegenerative diseases, including…”
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HSV-1 and Alzheimer's disease: more than a hypothesis by Piacentini, Roberto, De Chiara, Giovanna, Li Puma, Domenica D, Ripoli, Cristian, Marcocci, Maria E, Garaci, Enrico, Palamara, Anna T, Grassi, Claudio

“…Among the multiple factors concurring to Alzheimer's disease (AD) pathogenesis, greater attention should be devoted to the role played by infectious agents…”
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Neuromodulatory Action of Picomolar Extracellular Aβ42 Oligomers on Presynaptic and Postsynaptic Mechanisms Underlying Synaptic Function and Memory by Gulisano, Walter, Melone, Marcello, Ripoli, Cristian, Tropea, Maria Rosaria, Li Puma, Domenica D, Giunta, Salvatore, Cocco, Sara, Marcotulli, Daniele, Origlia, Nicola, Palmeri, Agostino, Arancio, Ottavio, Conti, Fiorenzo, Grassi, Claudio, Puzzo, Daniela

“…Failure of anti-amyloid-β peptide (Aβ) therapies against Alzheimer's disease (AD), a neurodegenerative disorder characterized by high amounts of the peptide in…”
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Genetic deletion of α7 nicotinic acetylcholine receptors induces an age-dependent Alzheimer’s disease-like pathology by Tropea, Maria Rosaria, Li Puma, Domenica D., Melone, Marcello, Gulisano, Walter, Arancio, Ottavio, Grassi, Claudio, Conti, Fiorenzo, Puzzo, Daniela

“…•α7nAChR deletion causes an impairment of hippocampal synaptic plasticity and memory in 12-month-old mice.•α7 KO mice present an age-dependent increase of…”
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Intracellular Accumulation of Amyloid-  (A ) Protein Plays a Major Role in A -Induced Alterations of Glutamatergic Synaptic Transmission and Plasticity by Ripoli, C., Cocco, S., Li Puma, D. D., Piacentini, R., Mastrodonato, A., Scala, F., Puzzo, D., D'Ascenzo, M., Grassi, C.

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Effects of different amyloid β-protein analogues on synaptic function by Ripoli, Cristian, Piacentini, Roberto, Riccardi, Elisa, Leone, Lucia, Li Puma, Domenica D, Bitan, Gal, Grassi, Claudio

“…Abstract Perisynaptic accumulations of amyloid β-protein (Aβ) play a critical role in the synaptic dysfunction underlying the cognitive impairment observed in…”
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Extremely low-frequency electromagnetic fields enhance the survival of newborn neurons in the mouse hippocampus by Podda, Maria V., Leone, Lucia, Barbati, Saviana A., Mastrodonato, Alessia, Li Puma, Domenica D., Piacentini, Roberto, Grassi, Claudio

“…In recent years, much effort has been devoted to identifying stimuli capable of enhancing adult neurogenesis, a process that generates new neurons throughout…”
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The effect of amyloid-β peptide on synaptic plasticity and memory is influenced by different isoforms, concentrations, and aggregation status by Gulisano, Walter, Melone, Marcello, Li Puma, Domenica D., Tropea, Maria Rosaria, Palmeri, Agostino, Arancio, Ottavio, Grassi, Claudio, Conti, Fiorenzo, Puzzo, Daniela

“…The increase of oligomeric amyloid-beta (oAβ) has been related to synaptic dysfunction, thought to be the earliest event in Alzheimer's disease…”
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Intracellular accumulation of amyloid-β (Aβ) protein plays a major role in Aβ-induced alterations of glutamatergic synaptic transmission and plasticity by Ripoli, Cristian, Cocco, Sara, Li Puma, Domenica D, Piacentini, Roberto, Mastrodonato, Alessia, Scala, Federico, Puzzo, Daniela, D'Ascenzo, Marcello, Grassi, Claudio

“…Intracellular accumulation of amyloid-β (Aβ) protein has been proposed as an early event in AD pathogenesis. In patients with mild cognitive impairment,…”
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Focus on biological identity of endothelial progenitors cells by Zaccone, V, Flore, R, Santoro, L, De Matteis, G, Giupponi, B, Li Puma, D D, Santoliquido, A

“…Circulating Endothelial Progenitor Cells (EPCs) were discovered by Asahara et al in 1997 and defined as bone marrow CD34+/KDR+ cells endowed with angiogenic…”
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Tau is not necessary for amyloid-β-induced synaptic and memory impairments by Puzzo, Daniela, Argyrousi, Elentina K, Staniszewski, Agnieszka, Zhang, Hong, Calcagno, Elisa, Zuccarello, Elisa, Acquarone, Erica, Fa', Mauro, Li Puma, Domenica D, Grassi, Claudio, D'Adamio, Luciano, Kanaan, Nicholas M, Fraser, Paul E, Arancio, Ottavio

“…The amyloid hypothesis posits that the amyloid-beta (Aβ) protein precedes and requires microtubule-associated protein tau in a sort of trigger-bullet mechanism…”
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Tau is not necessary for amyloid-β–induced synaptic and memory impairments by Puzzo, Daniela, Argyrousi, Elentina K, Staniszewski, Agnieszka, Zhang, Hong, Calcagno, Elisa, Zuccarello, Elisa, Acquarone, Erica, Fa, Mauro, Puma, Domenica D Li, Grassi, Claudio, D'Adamio, Luciano, Kanaan, Nicholas M, Fraser, Paul E, Arancio, Ottavio

“…The amyloid hypothesis posits that the amyloid-beta (Aß) protein precedes and requires microtubule-associated protein tau in a sort of trigger-bullet mechanism…”
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Tau is not necessary for amyloid-[beta]-induced synaptic and memory impairments by Puzzo, Daniela, Argyrousi, Elentina K, Staniszewski, Agnieszka, Zhang, Hong, Calcagno, Elisa, Zuccarello, Elisa, Acquarone, Erica, Fa', Mauro, Puma, Domenica D. Li, Grassi, Claudio, D'Adamio, Luciano, Kanaan, Nicholas M, Fraser, Paul E, Arancio, Ottavio

“…The amyloid hypothesis posits that the amyloid-beta (A[beta]) protein precedes and requires microtubule-associated protein tau in a sort of trigger-bullet…”
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A Bioengineering Strategy to Control ADAM10 Activity in Living Cells by Pastore, Francesco, Battistoni, Martina, Sollazzo, Raimondo, Renna, Pietro, Paciello, Fabiola, Li Puma, Domenica Donatella, Barone, Eugenio, Dagliyan, Onur, Ripoli, Cristian, Grassi, Claudio

“…A Disintegrin and Metalloprotease 10, also known as ADAM10, is a cell surface protease ubiquitously expressed in mammalian cells where it cuts several membrane…”
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Effects of different amyloid [beta]-protein analogues on synaptic function by Ripoli, Cristian, Piacentini, Roberto, Riccardi, Elisa, Leone, Lucia, Li Puma, Domenica D, Bitan, Gal, Grassi, Claudio

“…Perisynaptic accumulations of amyloid [beta]-protein (A[beta]) play a critical role in the synaptic dysfunction underlying the cognitive impairment observed in…”
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LTP and memory impairment caused by extracellular A[beta] and Tau oligomers is APP-dependent by Puzzo, Daniela, Piacentini, Roberto, Fá, Mauro, Gulisano, Walter, Li Puma, Domenica D, Staniszewski, Agnes, Zhang, Hong, Tropea, Maria Rosaria, Cocco, Sara, Palmeri, Agostino, Fraser, Paul, D'Adamio, Luciano, Grassi, Claudio, Arancio, Ottavio

“…The concurrent application of subtoxic doses of soluble oligomeric forms of human amyloid-beta (oA[beta]) and Tau (oTau) proteins impairs memory and its…”
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HSV-1 and Alzheimer’s disease: more than a hypothesis by Piacentini, Roberto, De Chiara, Giovanna, Li Puma, Domenica D., Ripoli, Cristian, Marcocci, Maria E., Garaci, Enrico, Palamara, Anna T., Grassi, Claudio

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