Search Results - "Li, Yongwen"

HOTAIR, a long noncoding RNA, is a marker of abnormal cell cycle regulation in lung cancer by Liu, Minghui, Zhang, Hongyi, Li, Ying, Wang, Rui, Li, Yongwen, Zhang, Hongbing, Ren, Dian, Liu, Hongyu, Kang, Chunsheng, Chen, Jun

“…Dysregulation of the cell cycle is a key indicator of tumors, including lung cancer. Recently, the study of cell cycle inhibitors has made great progress in…”
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High intensity focused ultrasound-responsive release behavior of PLA-b-PEG copolymer micelles by Zhang, Hongji, Xia, Hesheng, Wang, Jie, Li, Yongwen

“…Poly(lactic acid) (PLA) was synthesized by solution polycondensation of L-lactic acid and further reacted with dihydroxyl poly(ethylene glycol) (PEG) to obtain…”
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Protective effect of cinnamon polyphenols against STZ-diabetic mice fed high-sugar, high-fat diet and its underlying mechanism by Li, Rong, Liang, Tao, Xu, Lingyuan, Li, Yongwen, Zhang, Shijun, Duan, Xiaoqun

“…[Display omitted] ► Cinnamon polyphenols (CPS) is a potential agent for the treatment of diabetes. ► CPS exerts the hypoglycemic and hypolipidemic effects. ►…”
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ARID1A, ARID1B, and ARID2 Mutations Serve as Potential Biomarkers for Immune Checkpoint Blockade in Patients With Non-Small Cell Lung Cancer by Zhu, Guangsheng, Shi, Ruifeng, Li, Yongwen, Zhang, Zihe, Xu, Songlin, Chen, Chen, Cao, Peijun, Zhang, Hongbing, Liu, Minghui, Pan, Zhenhua, Liu, Hongyu, Chen, Jun

“…Worldwide, non-small cell lung cancer (NSCLC) has the highest morbidity and mortality of all malignancies. The lack of responsiveness to checkpoint inhibitors…”
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EZH2 inhibitors reverse resistance to gefitinib in primary EGFR wild-type lung cancer cells by Gong, Hao, Li, Yongwen, Yuan, Yin, Li, Weiting, Zhang, Hongbing, Zhang, Zihe, Shi, Ruifeng, Liu, Minghui, Liu, Chao, Chen, Chen, Liu, Hongyu, Chen, Jun

“…Lung cancer is the leading cause of cancer-related deaths worldwide. Non-small cell lung cancer (NSCLC) is the most common type of lung cancer. In traditional…”
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Circular RNA 0001789 sponges miR-140-3p and regulates PAK2 to promote the progression of gastric cancer by You, Jun, Chen, Yinan, Chen, Donghan, Li, Yongwen, Wang, Tinghao, Zhu, Jingtao, Hong, Qingqi, Li, Qiyuan

“…Gastric cancer (GC) is the third-leading cause of cancer-associated mortalities globally. The deregulation of circular RNAs (circRNAs) and microRNAs (miRNAs or…”
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Single-Cell Transcriptomics Unveils the Dedifferentiation Mechanism of Lung Adenocarcinoma Stem Cells by Pan, Zhenhua, Zhang, Meidi, Zhang, Fengyu, Pan, Hongli, Li, Yongwen, Shao, Yi, Yuan, Xin, Wang, Ju, Chen, Jun

“…Lung adenocarcinoma (LUAD) is a major subtype of lung cancer, and its prognosis is still poor due to therapy resistance, metastasis, and recurrence. In recent…”
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Exploring the therapeutic potential of targeting polycomb repressive complex 2 in lung cancer by Gao, Min, Li, Yongwen, Cao, Peijun, Liu, Hongyu, Chen, Jun, Kang, Shirong

“…The pathogenesis of lung cancer (LC) is a multifaceted process that is influenced by a variety of factors. Alongside genetic mutations and environmental…”
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Puerarin mediates hepatoprotection against CCl4-induced hepatic fibrosis rats through attenuation of inflammation response and amelioration of metabolic function by Li, Rong, Xu, Lingyuan, Liang, Tao, Li, Yongwen, Zhang, Shijun, Duan, Xiaoqun

“…► Puerarin treatment is a candidate of anti-fibrosis. ► Puerarin effectively regulates serum enzymes. ► Puerarin attenuates inflammation response in liver…”
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Clinical significance of EML4-ALK fusion gene and association with EGFR and KRAS gene mutations in 208 Chinese patients with non-small cell lung cancer by Li, Ying, Li, Yongwen, Yang, Tong, Wei, Sen, Wang, Jing, Wang, Min, Wang, Yuli, Zhou, Qinghua, Liu, Hongyu, Chen, Jun

“…The EML4-ALK fusion gene has been recently identified in a small subset of non-small cell lung cancer (NSCLC) patients who respond positively to ALK…”
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miR-182 suppresses invadopodia formation and metastasis in non-small cell lung cancer by targeting cortactin gene by Li, Yongwen, Zhang, Hongbing, Gong, Hao, Yuan, Yin, Li, Ying, Wang, Cong, Li, Weiting, Zhang, Zihe, Liu, Minghui, Liu, Hongyu, Chen, Jun

“…Metastasis is the leading cause of cancer mortality and is a major hurdle for lung cancer treatment. Invadopodia, which are cancer-specific protrusive…”
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Pan-cancer analysis predict that FAT1 is a therapeutic target and immunotherapy biomarker for multiple cancer types including non-small cell lung cancer by Ding, Chen, Huang, Hua, Wu, Di, Chen, Chen, Hua, Yu, Liu, Jinghao, Li, Yongwen, Liu, Hongyu, Chen, Jun

“…FAT1, a substantial transmembrane protein, plays a pivotal role in cellular adhesion and cell signaling. Numerous studies have documented frequent alterations…”
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EML4-ALK-mediated activation of the JAK2-STAT pathway is critical for non-small cell lung cancer transformation by Li, Ying, Li, Yongwen, Zhang, Hongbing, Shi, Ruifeng, Zhang, Zihe, Liu, Hongyu, Chen, Jun

“…Abstract Background The echinoderm microtubule-associated protein-like-4 anaplastic lymphoma kinase (EML4-ALK) fusion gene was identified in a subset of…”
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Lung microbiota: Unexploited treasure hidden in the immune microenvironment of lung cancer by Shi, Ruifeng, Li, Yongwen, Liu, Hongyu, Chen, Jun

“…With extensive research on the mechanism of lung cancer occurrence, studies have discovered that the development and progression of cancer are associated with…”
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Cell-autonomous immune gene expression is repressed in pulmonary neuroendocrine cells and small cell lung cancer by Cai, Ling, Liu, Hongyu, Huang, Fang, Fujimoto, Junya, Girard, Luc, Chen, Jun, Li, Yongwen, Zhang, Yu-An, Deb, Dhruba, Stastny, Victor, Pozo, Karine, Kuo, Christin S., Jia, Gaoxiang, Yang, Chendong, Zou, Wei, Alomar, Adeeb, Huffman, Kenneth, Papari-Zareei, Mahboubeh, Yang, Lin, Drapkin, Benjamin, Akbay, Esra A., Shames, David S., Wistuba, Ignacio I., Wang, Tao, Johnson, Jane E., Xiao, Guanghua, DeBerardinis, Ralph J., Minna, John D., Xie, Yang, Gazdar, Adi F.

“…Small cell lung cancer (SCLC) is classified as a high-grade neuroendocrine (NE) tumor, but a subset of SCLC has been termed “variant” due to the loss of NE…”
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L3MBTL1, a polycomb protein, promotes Osimertinib acquired resistance through epigenetic regulation of DNA damage response in lung adenocarcinoma by Zhang, Zihe, Li, Yongwen, Shi, Ruifeng, Jia, Chaoyi, Xu, Songlin, Zhu, Guangsheng, Cao, Peijun, Huang, Hua, Li, Xuanguang, Zhang, Hongbing, Liu, Minghui, Chen, Chen, Liu, Hongyu, Kang, Chunsheng, Chen, Jun

“…Osimertinib is a third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (EGFR-TKI) approved for patients with EGFR T790M resistance…”
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Myofibroblasts derived type V collagen promoting tissue mechanical stress and facilitating metastasis and therapy resistance of lung adenocarcinoma cells by Zhu, Guangsheng, Wang, Yanan, Wang, Yingjie, Huang, Hua, Li, Boshi, Chen, Peijie, Chen, Chen, Zhang, Hongbing, Li, Yongwen, Liu, Hongyu, Chen, Jun

“…Lung cancer is a leading cause of cancer-related mortality globally, with a dismal 5-year survival rate, particularly for Lung Adenocarcinoma (LUAD)…”
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Pulmonary rehabilitation integrated coached exercise training for patients with COPD: a study protocol for a randomized controlled trial by Jing, Yuting, Ma, Yuying, Zhang, Hongxing, Wu, Zhenhu, Li, Yongwen, Li, Haoxuan, Huang, Minling, Lin, Lin, Xu, Yinji

“…Chronic obstructive pulmonary disease (COPD) is the most common chronic lung disease creating an immense burden on social health care systems. Pulmonary…”
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Full-Length Transcriptome Sequencing Analysis of Differentially Expressed Genes and Pathways After Treatment of Psoriasis With Oxymatrine by Xue, Xiaoxiao, Yu, Jiayu, Li, Cheng, Wang, Fang, Guo, Yatao, Li, Yongwen, Shi, Huijuan

“…Psoriasis is a recurrent chronic inflammatory skin disease. Unlike many of the latest psoriasis treatments that only confer limited curative effects and have…”
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Methyl ferulic acid ameliorates prolonged high insulin-induced insulin release and synthesis in pancreatic β-cells via the miR-378b–PI3K–AKT pathway by Liang, Yanqing, Chen, Qi, Zhou, Ermei, Bi, Jianghui, Wang, Jia, Li, YongWen, Li, Li

“…[Display omitted] •MFA reversed insulin-induced upregulation of miR-378b in vitro and in vivo.•MFA increased expressions of insulin receptor and p110α as…”
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