Search Results - "Li, Yitang"

Pretreatment with phosphatase and tensin homolog deleted on chromosome 10 (PTEN) inhibitor SF1670 augments the efficacy of granulocyte transfusion in a clinically relevant mouse model by Li, Yitang, Prasad, Amit, Jia, Yonghui, Roy, Saurabh Ghosh, Loison, Fabien, Mondal, Subhanjan, Kocjan, Paulina, Silberstein, Leslie E., Ding, Sheng, Luo, Hongbo R.

“…The clinical outcome of granulocyte transfusion therapy is often hampered by short ex vivo shelf life, inefficiency of recruitment to sites of inflammation,…”
Get full text

Small-molecule screen identifies reactive oxygen species as key regulators of neutrophil chemotaxis by Hattori, Hidenori, Subramanian, Kulandayan K, Sakai, Jiro, Jia, Yonghui, Li, Yitang, Porter, Timothy F, Loison, Fabien, Sarraj, Bara, Kasorn, Anongnard, Jo, Hakryul, Blanchard, Catlyn, Zirkle, Dorothy, McDonald, Douglas, Pai, Sung-Yun, Serhan, Charles N, Luo, Hongbo R

“…Neutrophil chemotaxis plays an essential role in innate immunity, but the underlying cellular mechanism is still not fully characterized. Here, using a…”
Get full text

Deactivation of Akt by a small molecule inhibitor targeting pleckstrin homology domain and facilitating Akt ubiquitination by Jo, Hakryul, Lo, Pang-Kuo, Li, Yitang, Loison, Fabien, Green, Sarah, Wang, Jake, Silberstein, Leslie E, Ye, Keqiang, Chen, Hexin, Luo, Hongbo R

“…The phosphatidylinositol-3,4,5-triphosphate (PIP3) binding function of pleckstrin homology (PH) domain is essential for the activation of oncogenic Akt/PKB…”
Get full text

PTEN negatively regulates engulfment of apoptotic cells by modulating activation of Rac GTPase by Mondal, Subhanjan, Ghosh-Roy, Saurabh, Loison, Fabien, Li, Yitang, Jia, Yonghui, Harris, Chad, Williams, David A, Luo, Hongbo R

“…Efficient clearance of apoptotic cells by phagocytes (efferocytosis) is critical for normal tissue homeostasis and regulation of the immune system. Apoptotic…”
Get full text

Targeted deletion of tumor suppressor PTEN augments neutrophil function and enhances host defense in neutropenia-associated pneumonia by Li, Yitang, Jia, Yonghui, Pichavant, Muriel, Loison, Fabien, Sarraj, Bara, Kasorn, Anongnard, You, Jian, Robson, Bryanne E., Umetsu, Dale T., Mizgerd, Joseph P., Ye, Keqiang, Luo, Hongbo R.

“…Neutropenia and related infections are the most important dose-limiting toxicities in anticancer chemotherapy and radiotherapy. In this study, we explored a…”
Get full text

Focal Adhesion Kinase Regulates Pathogen-Killing Capability and Life Span of Neutrophils via Mediating Both Adhesion-Dependent and -Independent Cellular Signals by Kasorn, Anongnard, Alcaide, Pilar, Jia, Yonghui, Subramanian, Kulandayan K, Sarraj, Bara, Li, Yitang, Loison, Fabien, Hattori, Hidenori, Silberstein, Leslie E, Luscinskas, William F, Luo, Hongbo R

“…Various neutrophil functions such as phagocytosis, superoxide production, and survival are regulated by integrin signaling. Despite the essential role of focal…”
Get full text

Inositol trisphosphate 3-kinase B (InsP3KB) as a physiological modulator of myelopoiesis by Jia, Yonghui, Loison, Fabien, Hattori, Hidenori, Li, Yitang, Erneux, Christophe, Park, Shin-Young, Gao, Chong, Chai, Li, Silberstein, Leslie E, Schurmans, Stephane, Luo, Hongbo R

“…Inositol trisphosphate 3-kinase B (InsP3KB) belongs to a family of kinases that convert inositol 1,4,5-trisphosphate (Ins(1,4,5)P3 or IP3) to inositol…”
Get full text

Wide-band RF receiver based on dual-OFC-based photonic channelization and spectrum stitching technique by Yang, Jiyao, Li, Ruoming, Dai, Yitang, Dong, Jingwen, Li, Wangzhe

“…A novel wide-band RF receiver based on a dual-OFC-based channelization and spectrum stitching technique is proposed and demonstrated experimentally. In the…”
Get full text

Leukotriene B4-Driven Neutrophil Recruitment to the Skin Is Essential for Allergic Skin Inflammation by Oyoshi, Michiko K., He, Rui, Li, Yitang, Mondal, Subhanjan, Yoon, Juhan, Afshar, Roshi, Chen, Mei, Lee, David M., Luo, Hongbo R., Luster, Andrew D., Cho, John S., Miller, Lloyd S., Larson, Allison, Murphy, George F., Geha, Raif S.

“…Scratching triggers skin flares in atopic dermatitis. We demonstrate that scratching of human skin and tape stripping of mouse skin cause neutrophil influx. In…”
Get full text

Inositol hexakisphosphate kinase 1 regulates neutrophil function in innate immunity by inhibiting phosphatidylinositol-(3,4,5)-trisphosphate signaling by Luo, Hongbo R, Prasad, Amit, Jia, Yonghui, Chakraborty, Anutosh, Li, Yitang, Jain, Supriya K, Zhong, Jia, Roy, Saurabh Ghosh, Loison, Fabien, Mondal, Subhanjan, Sakai, Jiro, Blanchard, Catlyn, Snyder, Solomon H

“…Inositol phosphates are widely produced in animal and plant tissues. Luo and colleagues demonstrate that the inositol phosphate InsP7 modulates membrane…”
Get full text

Inhibition of PAX3 by TGF-β Modulates Melanocyte Viability by Yang, Guang, Li, Yitang, Nishimura, Emi K., Xin, Hong, Zhou, Anyu, Guo, Yinshi, Dong, Liang, Denning, Mitchell F., Nickoloff, Brian J., Cui, Rutao

“…The protein encoded by paired-box homeotic gene 3 ( PAX3) is a key regulator of the microphthalmia-associated transcription factor ( Mitf) in the melanocyte…”
Get full text

Myeloid-Specific Deletion of Tumor Suppressor PTEN Augments Neutrophil Transendothelial Migration during Inflammation by Sarraj, Bara, Massberg, Steffen, Li, Yitang, Kasorn, Anongnard, Subramanian, Kulandayan, Loison, Fabien, Silberstein, Leslie E, von Andrian, Ulrich, Luo, Hongbo R

“…Phosphatidylinositol 3,4,5-trisphosphate (PIP(3)) is a second messenger that is involved in a number of cell activities including cell growth, proliferation,…”
Get full text

LTB4 driven neutrophil recruitment to the skin is essential for allergic skin inflammation (125.17) by Oyoshi, Michiko, He, Rui, Li, Yitang, Yoon, Juhan, Afshar, Roshi, Chen, Mei, Lee, David, Luo, Hongbo, Luster, Andrew, Larson, Allison, Murphy, George, Geha, Raif

“…Scratching triggers skin flares in atopic dermatitis (AD), a disease marked by itching and allergic skin inflammation. Scratching of human skin, and tape…”
Get full text

FreeMotion: MoCap-Free Human Motion Synthesis with Multimodal Large Language Models by Zhang, Zhikai, Li, Yitang, Huang, Haofeng, Lin, Mingxian, Yi, Li

“…Human motion synthesis is a fundamental task in computer animation. Despite recent progress in this field utilizing deep learning and motion capture data,…”
Get full text

Leukotriene B4 Driven Neutrophil Recruitment to the Skin Is Essential for Allergic Skin Inflammation by Oyoshi, Michiko K., PhD, He, Rui, Li, Yitang, Mondal, Subhanjan, Yoon, Juhan, Afshar, Roshi, Chen, Mei, Lee, David M., MD, PhD, Luo, Hongbo, Luster, Andrew D., MD, PhD, Cho, John, Miller, Lloyd, Larson, Allison, Murphy, George, Geha, Raif, MD

Get full text

The effective operation range extension of micro manipulation system by Xin Zhao, Mingzhu Sun, Yitang Li, Xin Yin, Weiguang Zhang, Guizhang Lu

“…As for micro-manipulation system, not only does it need high operation precision, but also it should have huge operation range. According to electromechanical…”
Get full text

Inositol hexakisphosphate kinase 1 (InsP6K1) regulates neutrophil function in innate immunity by inhibiting PtdIns(3,4,5)P3 signaling by Prasad, Amit, Jia, Yonghui, Chakraborty, Anutosh, Li, Yitang, Jain, Supriya K., Zhong, Jia, Roy, Saurabh Ghosh, Loison, Fabien, Mondal, Subhanjan, Sakai, Jiro, Blanchard, Catlyn, Snyder, Solomon H., Luo, Hongbo R.

“…Inositol phosphates (InsP) are widely produced throughout animal and plant tissues. Diphosphoinositol pentakisphosphate (InsP7) contains an energetic…”
Get full text

Focal Adhesion Kinase Regulates Pathogen-Killing Capability and Life Span of Neutrophils via Mediating Both Adhesion-Dependent and -Independent Cellular Signals1 by Kasorn, Anongnard, Alcaide, Pilar, Jia, Yonghui, Subramanian, Kulandayan K., Sarraj, Bara, Li, Yitang, Loison, Fabien, Hattori, Hidenori, Silberstein, Leslie E., Luscinskas, William F., Luo, Hongbo R.

“…Various neutrophil functions such as phagocytosis, superoxide production, and survival are regulated by integrin signaling. Despite the essential role of focal…”
Get full text

Myeloid-Specific Deletion of Tumor Suppressor PTEN Augments Neutrophil Transendothelial Migration during Inflammation1 by Sarraj, Bara, Massberg, Steffen, Li, Yitang, Kasorn, Anongnard, Subramanian, Kulandayan, Loison, Fabien, Silberstein, Leslie E., von Andrian, Ulrich, Luo, Hongbo R.

“…Phosphatidylinositol 3,4,5-trisphosphate (PIP 3 ) is a second messenger that is involved in a number of cell activities including cell growth, proliferation,…”
Get full text

Targeted deletion of tumor suppressor PTEN enhances neutrophil function and prevents neutropenia‐associated pneumonia by Li, Yitang, Jia, Yonghui, Pichavant, Muriel, You, Jian, Robson, Bryanne, Umetsu, Dale, Mizgerd, Joseph, Ye, Keqiang, Luo, Hongbo

“…Neutropenia and related infections are the most important dose limiting toxicities in anti‐cancer chemo and radiotherapy. In this study, we explored a new…”
Get full text