Search Results - "Li, Ying‐Qin"
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Chemotherapeutic and targeted agents can modulate the tumor microenvironment and increase the efficacy of immune checkpoint blockades
Published in Molecular cancer (04-02-2021)“…The development of immune checkpoint blockade (ICB)-based immunotherapy has dramatically changed methods of cancer treatment. This approach triggers a durable…”
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2
Application of marine natural products in drug research
Published in Bioorganic & medicinal chemistry (01-04-2021)“…[Display omitted] •Marine invertebrates, plants and bacteria have produced new bioactive compounds.•Marine compounds show important therapeutic effects on…”
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Long Noncoding RNA FAM225A Promotes Nasopharyngeal Carcinoma Tumorigenesis and Metastasis by Acting as ceRNA to Sponge miR-590-3p/miR-1275 and Upregulate ITGB3
Published in Cancer research (Chicago, Ill.) (15-09-2019)“…Long noncoding RNAs (lncRNA) play important roles in the tumorigenesis and progression of cancers. However, the clinical significance of lncRNAs and their…”
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Development and validation of a gene expression-based signature to predict distant metastasis in locoregionally advanced nasopharyngeal carcinoma: a retrospective, multicentre, cohort study
Published in The lancet oncology (01-03-2018)“…Gene expression patterns can be used as prognostic biomarkers in various types of cancers. We aimed to identify a gene expression pattern for individual…”
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Gemcitabine and Cisplatin Induction Chemotherapy in Nasopharyngeal Carcinoma
Published in The New England journal of medicine (19-09-2019)“…Adding three cycles of induction chemotherapy with gemcitabine and cisplatin to concurrent chemoradiotherapy improved 3-year recurrence-free survival (85.3%,…”
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Congo Red‐Derived Carbon Dots: Simultaneously as Fluorescence Probe for Protein Aggregates, Inhibitor for Protein Aggregation, and Scavenger of Free Radicals
Published in Small (Weinheim an der Bergstrasse, Germany) (01-05-2023)“…The pathological aggregation of some proteins is claimed to be highly related to several human diseases, such as β‐amyloid 1–42 (Aβ42) to Alzheimer's disease…”
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Spontaneous remission of residual post‐therapy plasma Epstein–Barr virus DNA and its prognostic implication in nasopharyngeal carcinoma: A large‐scale, big‐data intelligence platform‐based analysis
Published in International journal of cancer (01-05-2019)“…Detectable post‐therapy plasma Epstein–Barr virus (EBV) DNA predicts poor survival in non‐metastatic nasopharyngeal carcinoma (NPC). However, some patients…”
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Single-cell transcriptomics reveals regulators underlying immune cell diversity and immune subtypes associated with prognosis in nasopharyngeal carcinoma
Published in Cell research (01-11-2020)“…Nasopharyngeal carcinoma (NPC) is an aggressive malignancy with extremely skewed ethnic and geographic distributions. Increasing evidence indicates that…”
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Prognostic significance of tumor‐infiltrating lymphocytes in nondisseminated nasopharyngeal carcinoma: A large‐scale cohort study
Published in International journal of cancer (15-06-2018)“…The American Joint Committee on Cancer (AJCC) staging system is inadequate for an accurate prognosis in nasopharyngeal carcinoma (NPC). Thus, new biomarkers…”
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10
Recent developments in the removal of metal-based engineered nanoparticles from the aquatic environments by adsorption
Published in Chemosphere (Oxford) (01-03-2022)“…Nowadays, metal-based engineered nanoparticles (m-ENPs) are ubiquitous in aquatic environments for their wide applications in all walks of life. m-ENPs have…”
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AR-induced long non-coding RNA LINC01503 facilitates proliferation and metastasis via the SFPQ-FOSL1 axis in nasopharyngeal carcinoma
Published in Oncogene (20-08-2020)“…Increasing evidence indicates that long non-coding RNAs (lncRNAs) play vital roles in the tumorigenesis and progression of cancers. However, the functions and…”
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FNDC3B 3′‐UTR shortening escapes from microRNA‐mediated gene repression and promotes nasopharyngeal carcinoma progression
Published in Cancer science (01-06-2020)“…Alternative polyadenylation (APA), which induces shortening of the 3′‐UTR, is emerging as an important feature in cancer development and progression…”
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Unraveling tumour microenvironment heterogeneity in nasopharyngeal carcinoma identifies biologically distinct immune subtypes predicting prognosis and immunotherapy responses
Published in Molecular cancer (11-01-2021)“…Currently, there is no strong evidence of the well-established biomarkers for immune checkpoint inhibitors (ICIs) in nasopharyngeal carcinoma (NPC). Here, we…”
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Array-based sensing of amyloidogenic proteins and discrimination of cancer by using different oxidants doped carbon nanodots as fluorescent probes
Published in Chemical engineering journal (Lausanne, Switzerland : 1996) (15-02-2022)“…[Display omitted] •A novel sensor array was constructed based on two oxidants doped carbon dots.•The array discriminated and quantified amyloidogenic proteins…”
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Genomic Analysis of Tumor Microenvironment Immune Types across 14 Solid Cancer Types: Immunotherapeutic Implications
Published in Theranostics (01-01-2017)“…We performed a comprehensive immuno-genomic analysis of tumor microenvironment immune types (TMITs), which is classified into four groups based on PD-L1+CD8A…”
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TRIM21 inhibits irradiation-induced mitochondrial DNA release and impairs antitumour immunity in nasopharyngeal carcinoma tumour models
Published in Nature communications (16-02-2023)“…Although radiotherapy can promote antitumour immunity, the mechanisms underlying this phenomenon remain unclear. Here, we demonstrate that the expression of…”
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Fast reversed‐phase liquid chromatographic separation of proteins by flow‐through poly(styrene‐co‐divinylbenzene) microspheres
Published in Journal of separation science (01-09-2019)“…With the explosive growth of the bioscience and biopharmaceuticals, the demand for high efficient analysis and separation of proteins is urgent…”
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Structural elucidation and antidiabetic activity of fucosylated chondroitin sulfate from sea cucumber Stichopus japonicas
Published in Carbohydrate polymers (15-06-2021)“…[Display omitted] •A fucosylated chondroitin sulfate was isolated from Stichopus japonicus (FCSsj).•The precise structure of FCSsj was investigated by NMR…”
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A lncRNA signature associated with tumor immune heterogeneity predicts distant metastasis in locoregionally advanced nasopharyngeal carcinoma
Published in Nature communications (30-05-2022)“…Increasing evidence has revealed the roles of long noncoding RNAs (lncRNAs) as tumor biomarkers. Here, we introduce an immune-associated nine-lncRNA signature…”
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ARNTL hypermethylation promotes tumorigenesis and inhibits cisplatin sensitivity by activating CDK5 transcription in nasopharyngeal carcinoma
Published in Journal of experimental & clinical cancer research (08-01-2019)“…Increasing evidence support an important role for DNA methylation in nasopharyngeal carcinoma (NPC). Here, we explored the role of circadian clock gene Aryl…”
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