Search Results - "Li, Yilai"

High-Throughput Cryo-EM Enabled by User-Free Preprocessing Routines by Li, Yilai, Cash, Jennifer N., Tesmer, John J.G., Cianfrocco, Michael A.

“…Single-particle cryoelectron microscopy (cryo-EM) continues to grow into a mainstream structural biology technique. Recent developments in data collection…”
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SMALL-LABS: Measuring Single-Molecule Intensity and Position in Obscuring Backgrounds by Isaacoff, Benjamin P., Li, Yilai, Lee, Stephen A., Biteen, Julie S.

“…Single-molecule and super-resolution imaging relies on successful, sensitive, and accurate detection of the emission from fluorescent molecules. Yet, despite…”
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High-resolution cryo-EM using beam-image shift at 200 keV by Cash, Jennifer N, Kearns, Sarah, Li, Yilai, Cianfrocco, Michael A

“…Recent advances in single-particle cryo-electron microscopy (cryo-EM) data collection utilize beam-image shift to improve throughput. Despite implementation on…”
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CryoSTAR: leveraging structural priors and constraints for cryo-EM heterogeneous reconstruction by Li, Yilai, Zhou, Yi, Yuan, Jing, Ye, Fei, Gu, Quanquan

“…Resolving conformational heterogeneity in cryogenic electron microscopy datasets remains an important challenge in structural biology. Previous methods have…”
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Cloud computing platforms to support cryo-EM structure determination by Li, Yilai, Cianfrocco, Michael A.

“…Leveraging the power of single-particle cryo-electron microscopy (cryo-EM) requires robust and accessible computational infrastructure. Here, we summarize the…”
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CryoRL : reinforcement learning enables efficient cryo-EM data collection by Cianfrocco, Michael, Li, Yilai, Fan, Quanfu, Cohn, John, Vas, Seychelle

“…Abstract only…”
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Single-Molecule DNA Polymerase Dynamics at a Bacterial Replisome in Live Cells by Liao, Yi, Li, Yilai, Schroeder, Jeremy W., Simmons, Lyle A., Biteen, Julie S.

“…PolC is one of two essential replicative DNA polymerases found in the Gram-positive bacterium Bacillus subtilis. The B. subtilis replisome is eukaryotic-like…”
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Visualizing bacterial DNA replication and repair with molecular resolution by Li, Yilai, Schroeder, Jeremy W, Simmons, Lyle A, Biteen, Julie S

“…[Display omitted] •Single-molecule microscopy resolves nm-scale positioning in vitro and in cells.•DNA replication proteins exchange rapidly at the bacterial…”
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cryoHub : a customizable web interface for cryo-EM data processing by Li, Yilai, Walls, Benjamin, Liu, Han, Yang, Le, Xiao, Rong, Li, Chuteng, Chen, Zhehao, Lugai, Chuck, Cianfrocco, Michael

“…Abstract only…”
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Dynamic Exchange of Two Essential DNA Polymerases during Replication and after Fork Arrest by Li, Yilai, Chen, Ziyuan, Matthews, Lindsay A., Simmons, Lyle A., Biteen, Julie S.

“…The replisome is a multiprotein machine responsible for the faithful replication of chromosomal and plasmid DNA. Using single-molecule super-resolution…”
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CryoHub : a user-friendly web-based platform for command-line scientific research tools specializing in cryo-EM analysis by Yang, Le, Li, Chuteng, Liu, Han, Xiao, Rong, Walls, Benjamin, Zhang, Yicheng, Zhang, Jiawen, Wang, Lueyu, Lugai, Chick, Lakshmikanth, Sujit, Vangos, Nicholas, Cianfrocco, Michael, Li, Yilai

“…Abstract only…”
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Super-Resolution Imaging of DNA Replisome Dynamics in Live Bacillus subtilis by Li, Yilai, Schroeder, Jeremy W., Liao, Yi, Chen, Ziyuan, Simmons, Lyle A., Biteen, Julie S.

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CryoRL: Reinforcement Learning Enables Efficient Cryo-EM Data Collection by Fan, Quanfu, Li, Yilai, Yao, Yuguang, Cohn, John, Liu, Sijia, Xu, Ziping, Vos, Seychelle, Cianfrocco, Michael

“…Single-particle cryo-electron microscopy (cryo-EM) has become one of the mainstream structural biology techniques because of its ability to determine…”
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Super-Resolution Imaging of DNA Replisome Dynamics in Live Bacillus Subtilis by Li, Yilai, Schroeder, Jeremy W., Liao, Yi, Simmons, Lyle A., Biteen, Julie S.

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Smart data collection for CryoEM by Bepler, Tristan, Borst, Andrew J., Bouvette, Jonathan, Cannone, Giuseppe, Chen, Songye, Cheng, Anchi, Cheng, Ao, Fan, Quanfu, Grollios, Fanis, Gupta, Harshit, Gupta, Meghna, Humphreys, Theo, Kim, Paul T., Kuang, Huihui, Li, Yilai, Noble, Alex J., Punjani, Ali, Rice, William J., Oscar S. Sorzano, Carlos, Stagg, Scott M., Strauss, Joshua, Yu, Lingbo, Carragher, Bridget, Potter, Clinton S.

“…[Display omitted] •Overview of discussions from Workshop on Smart Data Collection for CryoEM on April 6–7, 2022 in NYC.•Four smart data collection packages…”
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Super-Resolution Imaging of DNA Replisome Dynamics in Live Bacillus Subtilis by Li, Yilai, Schroeder, Jeremy W., Liao, Yi, Simmons, Lyle A., Biteen, Julie S.

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CryoFM: A Flow-based Foundation Model for Cryo-EM Densities by Zhou, Yi, Li, Yilai, Yuan, Jing, Gu, Quanquan

“…Cryo-electron microscopy (cryo-EM) is a powerful technique in structural biology and drug discovery, enabling the study of biomolecules at high resolution…”
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Fire Truck Firefighting Path Planning Based on Prediction and Multi-Agent Reinforcement Learning by Wang, Ximin, Li, Yilai, Lyu, Yifeng, Hu, Han

“…With the increasing global warming and extreme weather conditions, fires are becoming more frequent worldwide. Deep learning can be applied to fire prediction,…”
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CryoRL: Reinforcement Learning Enables Efficient Cryo-EM Data Collection by Fan, Quanfu, Li, Yilai, Yao, Yuguang, Cohn, John, Liu, Sijia, Vos, Seychelle M, Cianfrocco, Michael A

“…Single-particle cryo-electron microscopy (cryo-EM) has become one of the mainstream structural biology techniques because of its ability to determine…”
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Four years of free-air CO2 enrichment enhance soil C concentrations in a Chinese wheat field by Zhong, Shuang, Liang, Wenju, Lou, Yilai, Li, Qi, Zhu, Jianguo

“…Elevated atmospheric CO2 can influence soil C dynamics in agroecosystems. The effects of free-air CO2 enrichment （FACE） and N fertilization on soil organic C…”
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