Search Results - "Li, Xuqi"
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The interaction of perfluoroalkyl acids and a family history of diabetes on arthritis: analyses of 2011-2018 NHANES
Published in BMC public health (12-02-2024)“…Whether a family history of diabetes (FHD) and exposure to perfluoroalkyl acids (PFAAs) are correlated with an increased risk of developing arthritis remains…”
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Exosomal MiR-744 Inhibits Proliferation and Sorafenib Chemoresistance in Hepatocellular Carcinoma by Targeting PAX2
Published in Medical science monitor (25-09-2019)“…BACKGROUND Hepatocellular carcinoma (HCC) is a commonly occurring liver malignancy. Its prognosis remains unsatisfactory. Accumulating evidence has revealed…”
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SDF-1/CXCR4 signaling induces pancreatic cancer cell invasion and epithelial–mesenchymal transition in vitro through non-canonical activation of Hedgehog pathway
Published in Cancer letters (28-09-2012)“…Abstract In our previous study, we found that blockade of SDF-1/CXCR4 signaling inhibits pancreatic cancer cell migration and invasion in vitro . However, the…”
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Resveratrol reduces ROS-induced ferroptosis by activating SIRT3 and compensating the GSH/GPX4 pathway
Published in Molecular medicine (Cambridge, Mass.) (19-10-2023)“…Abstract Background Intestinal ischemia-reperfusion injury occurs in acute intestinal obstruction, intussusception, acute mesenteric artery embolism, and other…”
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Long-term survival outcomes and adverse effects of nasopharyngeal carcinoma patients treated with IMRT in a non-endemic region: a population-based retrospective study
Published in BMJ open (02-08-2021)“…ObjectivesTo evaluate the long-term survival outcomes and adverse effects of intensity-modulated radiotherapy (IMRT) for nasopharyngeal carcinoma (NPC) and to…”
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SIRT1 is a regulator of autophagy: Implications in gastric cancer progression and treatment
Published in FEBS letters (22-07-2015)“…Silent mating type information regulation 1 (SIRT1) is implicated in tumorigenesis through its effect on autophagy. In gastric cancer (GC), SIRT1 is a marker…”
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Sonic Hedgehog Paracrine Signaling Activates Stromal Cells to Promote Perineural Invasion in Pancreatic Cancer
Published in Clinical cancer research (15-08-2014)“…Pancreatic cancer is characterized by stromal desmoplasia and perineural invasion (PNI). We sought to explore the contribution of pancreatic stellate cells…”
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Activation of Nrf2 by Sulforaphane Inhibits High Glucose-Induced Progression of Pancreatic Cancer via AMPK Dependent Signaling
Published in Cellular physiology and biochemistry (01-01-2018)“…Background/Aims: Sulforaphane (SFN) is known for its potent bioactive properties, such as anti-inflammatory and anti-tumor effects. However, its anti-tumor…”
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High glucose microenvironment accelerates tumor growth via SREBP1-autophagy axis in pancreatic cancer
Published in Journal of experimental & clinical cancer research (11-07-2019)“…Diabetes is recognized to be a risk factor of pancreatic cancer, but the mechanism has not been fully elucidated. Sterol regulatory element binding protein 1…”
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The SDF-1/CXCR4 axis induces epithelial–mesenchymal transition in hepatocellular carcinoma
Published in Molecular and cellular biochemistry (01-07-2014)“…Hepatic stellate cells play a role in the migration process of hepatocellular carcinoma cells. Here, we address the role of the stromal-derived factor-1/CXC…”
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Hedgehog signaling regulates hypoxia induced epithelial to mesenchymal transition and invasion in pancreatic cancer cells via a ligand-independent manner
Published in Molecular cancer (20-06-2013)“…Hypoxia plays a vital role in cancer epithelial to mesenchymal transition (EMT) and invasion. However, it is not quite clear how hypoxia may contribute to…”
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Huaier extract restrains pancreatic cancer by suppressing Wnt/β-catenin pathway
Published in Biomedicine & pharmacotherapy (01-07-2020)“…Pancreatic cancer is a lethal disease, and new treatments need to be explored. Huaier extract is a traditional Chinese medicine that has been found to exert…”
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Resveratrol Ameliorates the Malignant Progression of Pancreatic Cancer by Inhibiting Hypoxia-induced Pancreatic Stellate Cell Activation
Published in Cell transplantation (01-01-2020)“…Pancreatic cancer is characterized by a hypoxic tumor microenvironment, which is primarily caused by massive fibrosis with pancreatic stellate cells (PSCs) as…”
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Reactive Oxygen Species and Targeted Therapy for Pancreatic Cancer
Published in Oxidative medicine and cellular longevity (01-01-2016)“…Pancreatic cancer is the fourth leading cause of cancer-related death in the United States. Reactive oxygen species (ROS) are generally increased in pancreatic…”
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What makes TMB an ambivalent biomarker for immunotherapy? A subtle mismatch between the sample-based design of variant callers and real clinical cohort
Published in Frontiers in immunology (25-05-2023)“…Tumor mutation burden (TMB) is a widely recognized biomarker for predicting the efficacy of immunotherapy. However, its use still remains highly controversial…”
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Inhibiting YAP expression suppresses pancreatic cancer progression by disrupting tumor-stromal interactions
Published in Journal of experimental & clinical cancer research (27-03-2018)“…Hippo/YAP pathway is known to be important for development, growth and organogenesis, and dysregulation of this pathway leads to tumor progression. We and…”
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Activating SIRT3 in peritoneal mesothelial cells alleviates postsurgical peritoneal adhesion formation by decreasing oxidative stress and inhibiting the NLRP3 inflammasome
Published in Experimental & molecular medicine (01-09-2022)“…Peritoneal adhesions (PAs) are a serious complication of abdominal surgery and negatively affect the quality of life of millions of people worldwide. However,…”
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SIRT1 mediated gastric cancer progression under glucose deprivation through the FoxO1-Rab7-autophagy axis
Published in Frontiers in oncology (24-05-2023)“…Silent mating type information regulator 2 homolog 1 (SIRT1) and autophagy have a two-way action (promoting cell death or survival) on the progression and…”
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miR-221/222 induces pancreatic cancer progression through the regulation of matrix metalloproteinases
Published in Oncotarget (10-06-2015)“…MicroRNAs are involved in the initiation and progression of pancreatic cancer. In this study, we showed that miR-221/222 is overexpressed in pancreatic cancer…”
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Targeting the cancer-stroma interaction: a potential approach for pancreatic cancer treatment
Published in Current pharmaceutical design (2012)“…Recent studies have demonstrated that the interaction between the cancer and the stroma, play a key role in the development of pancreatic cancer. The…”
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