Search Results - "Li, Xuecang"

SEdb: a comprehensive human super-enhancer database by Jiang, Yong, Qian, Fengcui, Bai, Xuefeng, Liu, Yuejuan, Wang, Qiuyu, Ai, Bo, Han, Xiaole, Shi, Shanshan, Zhang, Jian, Li, Xuecang, Tang, Zhidong, Pan, Qi, Wang, Yuezhu, Wang, Fan, Li, Chunquan

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Identification and analysis of a key long non‐coding RNAs (lncRNAs)‐associated module reveal functional lncRNAs in cardiac hypertrophy by Zhang, Jian, Feng, Chenchen, Song, Chao, Ai, Bo, Bai, Xuefeng, Liu, Yuejuan, Li, Xuecang, Zhao, Jianmei, Shi, Shengshu, Chen, Xin, Su, Xiaojie, Li, Chunquan

“…Cardiac hypertrophy (CH) is a common disease that originates from long‐term heart pressure overload and finally leads to heart failure. Recently, long…”
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MiRNA-Mediated Subpathway Identification and Network Module Analysis to Reveal Prognostic Markers in Human Pancreatic Cancer by Liu, Yuejuan, Cui, Yuxia, Bai, Xuefeng, Feng, Chenchen, Li, Meng, Han, Xiaole, Ai, Bo, Zhang, Jian, Li, Xuecang, Han, Junwei, Zhu, Jiang, Jiang, Yong, Pan, Qi, Wang, Fan, Xu, Mingcong, Li, Chunquan, Wang, Qiuyu

“…Pancreatic cancer (PC) remains one of the most lethal cancers. In contrast to the steady increase in survival for most cancers, the 5-year survival remains low…”
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SEdb: a comprehensive human super-enhancer database by Jiang, Yong, Qian, Fengcui, Bai, Xuefeng, Liu, Yuejuan, Wang, Qiuyu, Ai, Bo, Han, Xiaole, Shi, Shanshan, Zhang, Jian, Li, Xuecang, Tang, Zhidong, Pan, Qi, Wang, Yuezhu, Wang, Fan, Li, Chunquan

“…Abstract Super-enhancers are important for controlling and defining the expression of cell-specific genes. With research on human disease and biological…”
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TRCirc: a resource for transcriptional regulation information of circRNAs by Tang, Zhidong, Li, Xuecang, Zhao, Jianmei, Qian, Fengcui, Feng, Chenchen, Li, Yanyu, Zhang, Jian, Jiang, Yong, Yang, Yongsan, Wang, Qiuyu, Li, Chunquan

“…Abstract In recent years, high-throughput genomic technologies like chromatin immunoprecipitation sequencing (ChIp-seq) and transcriptome sequencing (RNA-seq)…”
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ENdb: a manually curated database of experimentally supported enhancers for human and mouse by Bai, Xuefeng, Shi, Shanshan, Ai, Bo, Jiang, Yong, Liu, Yuejuan, Han, Xiaole, Xu, Mingcong, Pan, Qi, Wang, Fan, Wang, Qiuyu, Zhang, Jian, Li, Xuecang, Feng, Chenchen, Li, Yanyu, Wang, Yuezhu, Song, Yiwei, Feng, Ke, Li, Chunquan

“…Abstract Enhancers are a class of cis-regulatory elements that can increase gene transcription by forming loops in intergenic regions, introns and exons…”
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ATACdb: a comprehensive human chromatin accessibility database by Wang, Fan, Bai, Xuefeng, Wang, Yuezhu, Jiang, Yong, Ai, Bo, Zhang, Yong, Liu, Yuejuan, Xu, Mingcong, Wang, Qiuyu, Han, Xiaole, Pan, Qi, Li, Yanyu, Li, Xuecang, Zhang, Jian, Zhao, Jun, Zhang, Guorui, Feng, Chenchen, Zhu, Jiang, Li, Chunquan

“…Abstract Accessible chromatin is a highly informative structural feature for identifying regulatory elements, which provides a large amount of information…”
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Acetylated cyclophilin A is a major mediator in hypoxia-induced autophagy and pulmonary vascular angiogenesis by Mao, Min, Yu, Xiufeng, Ge, Xin, Gu, Rui, Li, Qian, Song, Shasha, Zheng, Xiaodong, Shen, Tingting, Li, Xuecang, Fu, Yao, Li, Jiali, Zhu, Daling

“…BACKGROUND:Autophagy is a major intracellular degradation and recycling process that maintains cellular homeostasis, which is involved in structural and…”
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CanMethdb: a database for genome-wide DNA methylation annotation in cancers by Zhao, Jianmei, Qian, Fengcui, Li, Xuecang, Yu, Zhengmin, Zhu, Jiang, Yu, Rui, Zhao, Yue, Ding, Ke, Li, Yanyu, Yang, Yongsan, Pan, Qi, Chen, Jiaxin, Song, Chao, Wang, Qiuyu, Zhang, Jian, Wang, Guohua, Li, Chunquan

“…Abstract Motivation DNA methylation within gene body and promoters in cancer cells is well documented. An increasing number of studies showed that…”
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TRlnc: a comprehensive database for human transcriptional regulatory information of lncRNAs by Li, Yanyu, Li, Xuecang, Yang, Yongsan, Li, Meng, Qian, Fengcui, Tang, Zhidong, Zhao, Jianmei, Zhang, Jian, Bai, Xuefeng, Jiang, Yong, Zhou, Jianyuan, Zhang, Yuexin, Zhou, Liwei, Xie, Jianjun, Li, Enmin, Wang, Qiuyu, Li, Chunquan

“…Abstract Long noncoding RNAs (lncRNAs) have been proven to play important roles in transcriptional processes and biological functions. With the increasing…”
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GREAP: a comprehensive enrichment analysis software for human genomic regions by Yang, Yongsan, Qian, Fengcui, Li, Xuecang, Li, Yanyu, Zhou, Liwei, Wang, Qiuyu, Zhou, Xinyuan, Zhang, Jian, Song, Chao, Yu, Zhengmin, Cui, Ting, Feng, Chenchen, Zhu, Jiang, Shang, Desi, Liu, Jiaqi, Sun, Mengfei, Zhang, Yuexin, Tang, Huifang, Li, Chunquan

“…Abstract The rapid development of genomic high-throughput sequencing has identified a large number of DNA regulatory elements with abundant epigenetics…”
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ce‐Subpathway: Identification of ceRNA‐mediated subpathways via joint power of ceRNAs and pathway topologies by Feng, Chenchen, Song, Chao, Ning, Ziyu, Ai, Bo, Wang, Qiuyu, Xu, Yong, Li, Meng, Bai, Xuefeng, Zhao, Jianmei, Liu, Yuejuan, Li, Xuecang, Zhang, Jian, Li, Chunquan

“…Competing endogenous RNAs (ceRNAs) represent a novel mechanism of gene regulation that may mediate key subpathway regions and contribute to the altered…”
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Topologically inferring pathway activity toward precise cancer classification via integrating genomic and metabolomic data: prostate cancer as a case by Liu, Wei, Bai, Xuefeng, Liu, Yuejuan, Wang, Wei, Han, Junwei, Wang, Qiuyu, Xu, Yanjun, Zhang, Chunlong, Zhang, Shihua, Li, Xuecang, Ren, Zhonggui, Zhang, Jian, Li, Chunquan

“…Precise cancer classification is a central challenge in clinical cancer research such as diagnosis, prognosis and metastasis prediction. Most existing cancer…”
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The landscape of DNA methylation-mediated regulation of long non-coding RNAs in breast cancer by Zhang, Chunlong, Wang, Xinyu, Li, Xuecang, Zhao, Ning, Wang, Yihan, Han, Xiaole, Ci, Ce, Zhang, Jian, Li, Meng, Zhang, Yan

“…Although systematic studies have identified a host of long non-coding RNAs (lncRNAs) which are involved in breast cancer, the knowledge about the…”
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ce‐Subpathway: Identification of ce RNA ‐mediated subpathways via joint power of ce RNA s and pathway topologies by Feng, Chenchen, Song, Chao, Ning, Ziyu, Ai, Bo, Wang, Qiuyu, Xu, Yong, Li, Meng, Bai, Xuefeng, Zhao, Jianmei, Liu, Yuejuan, Li, Xuecang, Zhang, Jian, Li, Chunquan

“…Abstract Competing endogenous RNA s (ce RNA s) represent a novel mechanism of gene regulation that may mediate key subpathway regions and contribute to the…”
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Subpathway-CorSP: Identification of metabolic subpathways via integrating expression correlations and topological features between metabolites and genes of interest within pathways by Feng, Chenchen, Zhang, Jian, Li, Xuecang, Ai, Bo, Han, Junwei, Wang, Qiuyu, Wei, Taiming, Xu, Yong, Li, Meng, Li, Shang, Song, Chao, Li, Chunquan

“…Metabolic pathway analysis is a popular strategy for comprehensively researching metabolites and genes of interest associated with specific diseases. However,…”
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HiFreSP: A novel high-frequency sub-pathway mining approach to identify robust prognostic gene signatures by Li, Meng, Zhao, Jianmei, Li, Xuecang, Chen, Yang, Feng, Chenchen, Qian, Fengcui, Liu, Yuejuan, Zhang, Jian, He, Jianzhong, Ai, Bo, Ning, Ziyu, Liu, Wei, Bai, Xuefeng, Han, Xiaole, Wu, Zhiyong, Xu, Xiue, Tang, Zhidong, Pan, Qi, Xu, Liyan, Li, Chunquan, Wang, Qiuyu, Li, Enmin

“…Abstract With the increasing awareness of heterogeneity in cancers, better prediction of cancer prognosis is much needed for more personalized treatment…”
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CATA: a comprehensive chromatin accessibility database for cancer by Zhou, Jianyuan, Li, Yanshang, Cao, Haotian, Yang, Min, Chu, Lingyu, Li, Taisong, Yu, Zhengmin, Yu, Rui, Qiu, Bo, Wang, Qiuyu, Li, Xuecang, Xie, Jianjun

“…Accessible chromatin refers to the active regions of a chromosome that are bound by many transcription factors (TFs). Changes in chromatin accessibility play a…”
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Integration of pathway structure information into a reweighted partial Cox regression approach for survival analysis on high-dimensional gene expression data by Liu, Wei, Wang, Qiuyu, Zhao, Jianmei, Zhang, Chunlong, Liu, Yuejuan, Zhang, Jian, Bai, Xuefeng, Li, Xuecang, Feng, Houming, Liao, Mingzhi, Wang, Wei, Li, Chunquan

“…Accurately predicting the risk of cancer relapse or death is important for clinical utility. The emerging high-dimensional gene expression data provide the…”
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RWCFusion: identifying phenotype-specific cancer driver gene fusions based on fusion pair random walk scoring method by Zhao, Jianmei, Li, Xuecang, Yao, Qianlan, Li, Meng, Zhang, Jian, Ai, Bo, Liu, Wei, Wang, Qiuyu, Feng, Chenchen, Liu, Yuejuan, Bai, Xuefeng, Song, Chao, Li, Shang, Li, Enmin, Xu, Liyan, Li, Chunquan

“…While gene fusions have been increasingly detected by next-generation sequencing (NGS) technologies based methods in human cancers, these methods have…”
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