Search Results - "Li, Xu‐bo"
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Extracellular Vesicles Derived From Hypoxia-Conditioned Adipose-Derived Mesenchymal Stem Cells Enhance Lymphangiogenesis
Published in Cell transplantation (2022)“…Extracellular vesicles from adipose-derived mesenchymal stem cells (ADSCs) play an important role in lymphangiogenesis; however, the underlying mechanisms are…”
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Tanshinone IIA improves contextual fear‐ and anxiety‐like behaviors in mice via the CREB/BDNF/TrkB signaling pathway
Published in Phytotherapy research (01-10-2022)“…Posttraumatic stress disorder (PTSD) is one of the most common psychiatric diseases, which is characterized by the typical symptoms such as re‐experience,…”
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Mechanism of CNS regulation by irisin, a multifunctional protein
Published in Brain research bulletin (01-10-2022)“…Exercise not only builds up our body but also improves cognitive function. Skeletal muscle secretes myokine during exercise as a large reservoir of signaling…”
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Ruscogenin Exerts Anxiolytic‐Like Effect via Microglial NF‐κB/MAPKs/NLRP3 Signaling Pathways in Mouse Model of Chronic Inflammatory Pain
Published in Phytotherapy research (01-11-2024)“…ABSTRACT Long‐term inflammation can cause chronic pain and trigger patients' anxiety by sensitizing the central nervous system. However, effective drugs with…”
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Activation of LXRβ Signaling in the Amygdala Confers Anxiolytic Effects Through Rebalancing Excitatory and Inhibitory Neurotransmission upon Acute Stress
Published in Neurotherapeutics (01-07-2020)“…The balance of major excitatory (glutamate, Glu) and inhibitory (γ-aminobutyric acid, GABA), named as E/I neurotransmission, is critical for proper information…”
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Paeonol ameliorates CFA-induced inflammatory pain by inhibiting HMGB1/TLR4/NF-κB p65 pathway
Published in Metabolic brain disease (01-02-2021)“…The enhanced release of inflammatory cytokines mediated by high mobility group box1 (HMGB1) leads to pain sensation, and has been implicated in the etiology of…”
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Disrupting cannabinoid receptor interacting protein 1 rescues cognitive flexibility in long-term estrogen-deprived female mice
Published in Brain research bulletin (01-04-2022)“…Hormone therapy (HT) has failed to improve learning and memory in postmenopausal women according to recent clinical studies; however, the reason for failure of…”
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Dynamic recrystallization behavior of AZ31 magnesium alloy processed by alternate forward extrusion
Published in Frontiers of materials science (01-09-2017)“…One of the important factors that affect the microstructure and properties of extruded products is recrystallization behavior. Alternate forward extrusion…”
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Effect of ZBD-2 on chronic pain, depressive-like behaviors, and recovery of motor function following spinal cord injury in mice
Published in Behavioural brain research (30-03-2017)“…•ZBD-2 significantly attenuated the symptoms of chronic SCI-pain and pain-induced depressive-like behaviors.•ZBD-2 inhibited the decreases in the expression of…”
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FMRP acts as a key messenger for visceral pain modulation
Published in Molecular pain (2020)“…Visceral pain is a common clinical symptom, which is caused by mechanical stretch, spasm, ischemia and inflammation. Fragile X syndrome (FXS) with lack of…”
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Neuroprotective effects of oestrogen against oxidative toxicity through activation of G-protein-coupled receptor 30 receptor
Published in Clinical and experimental pharmacology & physiology (01-09-2011)“…Summary 1. 17‐β‐oestradiol (E2) plays a critical role in neuroprotection through both genomic and non‐genomic mechanisms. The aim of the present study was to…”
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Three-Dimensional Reconstruction Method for Machined Surface Topography Based on Gray Gradient Constraints
Published in Applied sciences (11-02-2019)“…In the modern engineering field, recovering the machined surface topography is important for studying mechanical product function and surface characteristics…”
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Investigation of Chip Deformation and Breaking with a Staggered Teeth BTA Tool in Deep Hole Drilling
Published in Metals (Basel ) (01-01-2019)“…The problem of chip breaking and evacuation is the key point of staggered teeth boring and trepanning association (BTA) drilling. The factors that influence…”
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Activation of GIPR Exerts Analgesic and Anxiolytic-Like Effects in the Anterior Cingulate Cortex of Mice
Published in Frontiers in endocrinology (Lausanne) (30-05-2022)“…Background Chronic pain is defined as pain that persists typically for a period of over six months. Chronic pain is often accompanied by an anxiety disorder,…”
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Neuroprotective effects of curculigoside against NMDA-induced neuronal excitoxicity in vitro
Published in Food and chemical toxicology (01-11-2012)“…► Curculigoside protects neurons against excitotoxicity induced by NMDA exposure. ► The neuroprotection of Curculigoside is related to inhibiting neuronal…”
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Anxiolytic-Like Effects of Translocator Protein (TSPO) Ligand ZBD-2 in an Animal Model of Chronic Pain
Published in Molecular pain (26-03-2015)“…The activation of Translocator protein (18 kDa) (TSPO) has been demonstrated to mediate rapid anxiolytic efficacy in stress response and stress-related…”
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A novel translocator protein 18 kDa ligand, ZBD-2, exerts neuroprotective effects against acute spinal cord injury
Published in Clinical and experimental pharmacology & physiology (01-10-2016)“…Summary Traumatic spinal cord injury (SCI) happens accidently and often leads to motor dysfunction due to a series of biochemical and pathological events and…”
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Neuroprotective effects of a novel translocator protein (18 kDa) ligand, ZBD-2, against focal cerebral ischemia and NMDA-induced neurotoxicity
Published in Clinical and experimental pharmacology & physiology (01-10-2015)“…Summary Ligands of the translocator protein (18 kDa) (TSPO) have demonstrated rapid anxiolytic efficacy in stress responses and stress‐related disorders. This…”
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The neuroprotective effect of praeruptorin C against NMDA-induced apoptosis through down-regulating of GluN2B-containing NMDA receptors
Published in Toxicology in vitro (01-03-2013)“…► Praeruptorin C significantly inhibited the neuronal apoptosis induced by NMDA exposure. ► The mechanism relies on reversing intracellular Ca2+ overload and…”
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Neuroprotective effects of oxymatrine against excitotoxicity partially through down-regulation of NR2B-containing NMDA receptors
Published in Phytomedicine (Stuttgart) (15-02-2013)“…Oxymatrine (OMT) is a major bioactive component derived from Sophora flavescens Ait (kushen), which is widely used in Chinese medicine. Recent studies have…”
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