Search Results - "Li, Xin V."
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Gut Mycobiota in Immunity and Inflammatory Disease
Published in Immunity (Cambridge, Mass.) (18-06-2019)“…The mammalian intestine is colonized by a wealth of microorganisms—including bacteria, viruses, protozoa, and fungi—that are all integrated into a functional…”
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Genetic manipulation of gut microbes enables single-gene interrogation in a complex microbiome
Published in Cell (03-02-2022)“…Hundreds of microbiota genes are associated with host biology/disease. Unraveling the causal contribution of a microbiota gene to host biology remains…”
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Macrophages Maintain Epithelium Integrity by Limiting Fungal Product Absorption
Published in Cell (15-10-2020)“…The colon is primarily responsible for absorbing fluids. It contains a large number of microorganisms including fungi, which are enriched in its distal…”
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Mucosal fungi promote gut barrier function and social behavior via Type 17 immunity
Published in Cell (03-03-2022)“…Fungal communities (the mycobiota) are an integral part of the gut microbiota, and the disruption of their integrity contributes to local and gut-distal…”
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Immune regulation by fungal strain diversity in inflammatory bowel disease
Published in Nature (London) (24-03-2022)“…The fungal microbiota (mycobiota) is an integral part of the complex multikingdom microbial community colonizing the mammalian gastrointestinal tract and has…”
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Human gut mycobiota tune immunity via CARD9-dependent induction of anti-fungal IgG antibodies
Published in Cell (18-02-2021)“…Antibodies mediate natural and vaccine-induced immunity against viral and bacterial pathogens, whereas fungi represent a widespread kingdom of pathogenic…”
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Microbiota metabolism of intestinal amino acids impacts host nutrient homeostasis and physiology
Published in Cell host & microbe (08-05-2024)“…The intestine and liver are thought to metabolize dietary nutrients and regulate host nutrient homeostasis. Here, we find that the gut microbiota also reshapes…”
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Mycobiota-induced IgA antibodies regulate fungal commensalism in the gut and are dysregulated in Crohn’s disease
Published in Nature microbiology (01-12-2021)“…Secretory immunoglobulin A (sIgA) plays an important role in gut barrier protection by shaping the resident microbiota community, restricting the growth of…”
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Author Correction: Immune regulation by fungal strain diversity in inflammatory bowel disease
Published in Nature (London) (11-08-2022)Get full text
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Oral microbiota and host innate immune response in bisphosphonate-related osteonecrosis of the jaw
Published in International journal of oral science (01-12-2014)“…Bacterial biofilms have emerged as potential critical triggers in the pathogenesis of bisphosphonate(BP)-related osteonecrosis of the jaw(ONJ) or BRONJ. BRONJ…”
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