Search Results - "Li, Xiangrao"
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Inhibition of the lncRNA Mirt1 Attenuates Acute Myocardial Infarction by Suppressing NF-κB Activation
Published in Cellular physiology and biochemistry (01-01-2017)“…Background/Aims: The expression of a novel lncRNA, myocardial infarction associated transcript 1(Mirt1), has been shown to be upregulated in acute myocardial…”
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The LPS-inducible lncRNA Mirt2 is a negative regulator of inflammation
Published in Nature communications (11-12-2017)“…Toll-like receptors (TLRs) are a family of pattern recognition receptors (PRR) with a crucial function in innate immune responses. Activation of TLR4 signaling…”
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Renalase is a novel target gene of hypoxia-inducible factor-1 in protection against cardiac ischaemia-reperfusion injury
Published in Cardiovascular research (01-02-2015)“…Renalase, an enzyme that can metabolize catecholamine, was recently reported to attenuate the ischaemia/reperfusion (I/R)-induced cardiac injury. This work was…”
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IL‐38 attenuates myocardial ischemia–reperfusion injury by inhibiting macrophage inflammation
Published in Immunity, Inflammation and Disease (01-06-2023)“…Background Reperfusion therapy is the most effective approach to resolve coronary occlusion, but myocardial injury caused by excessive inflammation during…”
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Poly(ADP-Ribose) Polymerase 1 Promotes Oxidative-Stress-Induced Liver Cell Death via Suppressing Farnesoid X Receptor α
Published in Molecular and Cellular Biology (01-11-2013)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Identification of poly(ADP-ribose) polymerase-1 as a cell cycle regulator through modulating Sp1 mediated transcription in human hepatoma cells
Published in PloS one (19-12-2013)“…The transcription factor Sp1 is implicated in the activation of G0/G1 phase genes. Modulation of Sp1 transcription activities may affect G1-S checkpoint,…”
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CD9 exacerbates pathological cardiac hypertrophy through regulating GP130/STAT3 signaling pathway
Published in iScience (17-11-2023)“…CD9 is a member of the tetraspanin protein family, which has been widely studied in inflammation and cancer, but not in pathological cardiac hypertrophy. In…”
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Nkx2‐5 Is Expressed in Atherosclerotic Plaques and Attenuates Development of Atherosclerosis in Apolipoprotein E–Deficient Mice
Published in Journal of the American Heart Association (19-12-2016)“…Background NK2 homeobox 5 (Nkx2‐5) is a cardiac homeobox transcription factor that is expressed in a broad range of cardiac sublineages. Embryos lacking Nkx2‐5…”
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Role of CCR2 in the Development of Streptozotocin-Treated Diabetic Cardiomyopathy
Published in Diabetes (New York, N.Y.) (01-11-2019)“…CCR2 has been proven to play an important role in diabetes. However, the role of CCR2 in diabetic cardiomyopathy has not been examined. In this study, we…”
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PARP1-mediated PPARα poly(ADP-ribosyl)ation suppresses fatty acid oxidation in non-alcoholic fatty liver disease
Published in Journal of hepatology (01-05-2017)“…Graphical abstract…”
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Inhibition of Poly(ADP-Ribose) Polymerase-1 Protects Chronic Alcoholic Liver Injury
Published in The American journal of pathology (01-12-2016)“…Activation of Kupffer cells (KCs) by gut-derived endotoxin plays a pivotal role in the pathogenesis of alcoholic liver diseases (ALD). Limiting the activation…”
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PARP1-mediated PPARa poly(ADP-ribosyl)ation suppresses fatty acid oxidation in non-alcoholic fatty liver disease
Published in Journal of hepatology (01-05-2017)“…Background & Aims PARP1 is a key mediator of cellular stress responses and critical in multiple physiological and pathophysiological processes of cells…”
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Identification of Poly
Published in PloS one (19-12-2013)“…The transcription factor Sp1 is implicated in the activation of G0/G1 phase genes. Modulation of Sp1 transcription activities may affect G1-S checkpoint,…”
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Identification of Poly(ADP-Ribose) Polymerase-1 as a Cell Cycle Regulator through Modulating Sp1 Mediated Transcription in Human Hepatoma Cells: e82872
Published in PloS one (01-12-2013)“…The transcription factor Sp1 is implicated in the activation of G0/G1 phase genes. Modulation of Sp1 transcription activities may affect G1-S checkpoint,…”
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