Search Results - "Li, WanFang"
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Palladium-Catalyzed Carbonylative Synthesis of Benzoxazinones from N‑(o‑Bromoaryl)amides Using Paraformaldehyde as the Carbonyl Source
Published in Journal of organic chemistry (07-11-2014)“…Carbonylation reactions have been widely used in organic synthesis. However, the manipulation of toxic and pressurized carbon monoxide limited their…”
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2
Visible-Light-Induced Intermolecular Dearomative Cyclization of 2‑Bromo-1,3-dicarbonyl Compounds and Alkynes: Synthesis of Spiro[4.5]deca-1,6,9-trien-8-ones
Published in Organic letters (21-09-2018)“…A visible-light-induced photocatalytic intermolecular dearomative cyclization of 2-bromo-1,3-dicarbonyl compounds and alkynes afforded biologically important…”
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3
Role of Nrf2 in the antioxidation and oxidative stress induced developmental toxicity of honokiol in zebrafish
Published in Toxicology and applied pharmacology (15-06-2019)“…Honokiol, the main bioactive component of Magnolia officinalis, has a variety of pharmacological actions. However, its toxicity has rarely been reported…”
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The Applications of (Para)formaldehyde in Metal-Catalyzed Organic Synthesis
Published in Advanced synthesis & catalysis (16-11-2015)“…Paraformaldehyde (PFA), with the chemical formula CxHyOz, an infinite solid form of formaldehyde, is a very useful reagent in classical organic reactions…”
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Palladium-Catalyzed Aminosulfonylation of Aryl Iodides by using Na2SO3 as the SO2 Source
Published in European journal of organic chemistry (01-05-2014)“…We realized an interesting palladium‐catalyzed aminosulfonylation of aryl iodides by using Na2SO3 as a cheap SO2 source. In most cases, the yields were…”
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6
Possible adverse events of imidazole antifungal drugs during treatment of vulvovaginal candidiasis: analysis of the FDA Adverse Event Reporting System
Published in Scientific reports (24-06-2024)“…Azole antifungal drugs are commonly used to treat vulvovaginal candidiasis (VVC). The nephrotoxicity and developmental toxicity of azole drugs have not been…”
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Spatial-resolved metabolomics reveals tissue-specific metabolic reprogramming in diabetic nephropathy by using mass spectrometry imaging
Published in Acta pharmaceutica Sinica. B (01-11-2021)“…Detailed knowledge on tissue-specific metabolic reprogramming in diabetic nephropathy (DN) is vital for more accurate understanding the molecular pathological…”
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Preclinical Study of Antineoplastic Sinoporphyrin Sodium-PDT via In Vitro and In Vivo Models
Published in Molecules (Basel, Switzerland) (01-01-2017)“…Photodynamic therapy (PDT) investigations have seen stable increases and the development of new photosensitizers is a heated topic. Sinoporphyrin sodium is a…”
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Fraxinellone Induces Hepatotoxicity in Zebrafish through Oxidative Stress and the Transporters Pathway
Published in Molecules (Basel, Switzerland) (20-04-2022)“…Fraxinellone (FRA), a major active component from Cortex Dictamni, produces hepatotoxicity via the metabolization of furan rings by CYP450. However, the…”
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10
A Novel Domino Synthesis of Quinazolinediones by Palladium-Catalyzed Double Carbonylation
Published in Chemistry : a European journal (07-07-2014)“…Combining commercially available bromoanilines and bromobenzonitriles in a novel double carbonylation process allows for a straightforward synthesis of…”
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11
Integrated mass spectrometry imaging reveals spatial-metabolic alteration in diabetic cardiomyopathy and the intervention effects of ferulic acid
Published in Journal of pharmaceutical analysis (01-12-2023)“…Diabetic cardiomyopathy (DCM) is a metabolic disease and a leading cause of heart failure among people with diabetes. Mass spectrometry imaging (MSI) is a…”
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12
Unraveling the mechanism of ethyl acetate extract from Prismatomeris connata Y. Z. Ruan root in treating pulmonary fibrosis: insights from bioinformatics, network pharmacology, and experimental validation
Published in Frontiers in immunology (08-01-2024)“…Pulmonary fibrosis is a terminal lung disease characterized by fibroblast proliferation, extracellular matrix accumulation, inflammatory damage, and tissue…”
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13
Honokiol Microemulsion Causes Stage-Dependent Toxicity Via Dual Roles in Oxidation-Reduction and Apoptosis through FoxO Signaling Pathway
Published in Cells (Basel, Switzerland) (01-11-2022)“…Honokiol, the main bioactive extract of exhibits extensive therapeutic actions. Its treatment for advanced non-small cell lung cancer is undergoing clinical…”
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14
Ruthenium-Catalyzed Enantioselective Hydrogenation of Aryl-Pyridyl Ketones
Published in Journal of organic chemistry (06-01-2012)“…Various substituted aryl-pyridyl ketones were hydrogenated in the presence of Ru-XylSunPhos-Daipen bifunctional catalytic system with enantiomeric excesses up…”
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15
Enantioselective Hydrogenation of β‑Ketophosphonates with Chiral Ru(II) Catalysts
Published in Journal of organic chemistry (05-10-2012)“…Highly effective asymmetric hydrogenation of β-ketophosphonates in the presence of Ru–(S)-SunPhos as catalyst was realized; good to excellent…”
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16
Ru-Catalyzed Asymmetric Hydrogenation of γ-Heteroatom Substituted β-Keto Esters
Published in Journal of organic chemistry (18-11-2011)“…A series of enantiomerically pure γ-heteroatom substituted β-hydroxy esters were synthesized with high enantioselectivities (up to 99.1% ee) by hydrogenation…”
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Synthesis of (S)-7-Amino-5-azaspiro[2.4]heptane via Highly Enantioselective Hydrogenation of Protected Ethyl 1-(2-Aminoaceto)cyclopropanecarboxylates
Published in Journal of organic chemistry (15-04-2011)“…Highly effective asymmetric hydrogenation of protected ethyl 1-(2-aminoaceto)cyclopropane carboxylates in the presence of [RuCl(benzene)(S)-SunPhos]Cl was…”
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Transition Metal-free Methylation of Amines with Formaldehyde as the Reductant and Methyl Source
Published in Chimia (01-01-2015)“…A simple transition metal-free procedure using formal dehyde for the N,N-dimethylation and N-methylation of primary and secondary anilines is reported. The…”
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The applications of β‐keto amides for heterocycle synthesis
Published in Journal of heterocyclic chemistry (01-09-2022)“…β‐Keto amides have multiple nucleophilic and electrophilic reaction sites within their molecular structures, which make them excellent building blocks for the…”
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20
Nickel-catalyzed difunctionalization of allyl moieties using organoboronic acids and halides with divergent regioselectivities
Published in Chemical science (Cambridge) (21-01-2018)“…Efficient difunctionalization of alkenes allows the rapid construction of molecular complexity from simple building blocks in organic synthesis. We present…”
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