Search Results - "Li, W. S"
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Extracellular matrix hydrogel derived from decellularized tissues enables endodermal organoid culture
Published in Nature communications (11-12-2019)“…Organoids have extensive therapeutic potential and are increasingly opening up new avenues within regenerative medicine. However, their clinical application is…”
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2
Serine synthesis pathway inhibition cooperates with dietary serine and glycine limitation for cancer therapy
Published in Nature communications (14-01-2021)“…Many tumour cells show dependence on exogenous serine and dietary serine and glycine starvation can inhibit the growth of these cancers and extend survival in…”
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3
Cell-type-specific signaling networks in heterocellular organoids
Published in Nature methods (01-03-2020)“…Despite the widespread adoption of organoids as biomimetic tissue models, methods to comprehensively analyze cell-type-specific post-translational modification…”
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4
Reg4⁺ deep crypt secretory cells function as epithelial niche for Lgr5⁺ stem cells in colon
Published in Proceedings of the National Academy of Sciences - PNAS (13-09-2016)“…Leucine-rich repeat-containing G-protein coupled receptor 5-positive (Lgr5⁺) stem cells reside at crypt bottoms of the small and large intestine. Small…”
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Intestinal Stem Cell Niche: The Extracellular Matrix and Cellular Components
Published in Stem cells international (01-01-2017)“…The intestinal epithelium comprises a monolayer of polarised columnar cells organised along the crypt-villus axis. Intestinal stem cells reside at the base of…”
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6
Yap in regeneration and symmetry breaking
Published in Nature cell biology (01-06-2019)“…Yap signalling is crucial for intestinal regeneration, but its role is largely dispensable in homeostasis. Two studies now reveal Yap-dependent mechanisms of…”
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Targeting Wnt signaling in colorectal cancer. A Review in the Theme: Cell Signaling: Proteins, Pathways and Mechanisms
Published in American Journal of Physiology: Cell Physiology (15-10-2015)“…The evolutionarily conserved Wnt signaling pathway plays essential roles during embryonic development and tissue homeostasis. Notably, comprehensive genetic…”
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Biobased Composites by Photoinduced Polymerization of Cardanol Methacrylate with Microfibrillated Cellulose
Published in Materials (04-01-2022)“…Biobased monomers and green processes are key to producing sustainable materials. Cardanol, an aromatic compound obtained from cashew nut shells, may be…”
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Emission strength of airborne pathogens during toilet flushing
Published in Indoor air (01-01-2018)“…The flushing of toilets generates contaminated aerosols, the transmission of which may cause the spread of disease, particularly in the immunocompromised or…”
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Gene expression patterns of human colon tops and basal crypts and BMP antagonists as intestinal stem cell niche factors
Published in Proceedings of the National Academy of Sciences - PNAS (25-09-2007)“…Human colonic epithelial cell renewal, proliferation, and differentiation are stringently controlled by numerous regulatory pathways. To identify genetic…”
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11
Shear force induced monodisperse droplet formation in a microfluidic device by controlling wetting properties
Published in Lab on a chip (01-01-2006)“…Perpendicular flow is used to induce oil droplet breakup by using a capillary as water phase flow channel. It is a new route to produce monodisperse emulsions…”
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Fish-oil supplement has neutral effects on vascular and metabolic function but improves renal function in patients with Type 2 diabetes mellitus
Published in Diabetic medicine (01-01-2010)“…Diabet. Med. 27, 54–60 (2010) Aims Increased dietary fish‐oil consumption is associated with a reduced risk of coronary heart events and has pronounced…”
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13
On the thermodynamics of the difference between energy transfer rate and heat engine efficiency
Published in The European physical journal. ST, Special topics (01-06-2021)“…We study the difference between the energy transfer rate and the engine efficiency with a microscopic model, widely used in the theoretical description of…”
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14
The BMP antagonist follistatin-like 1 is required for skeletal and lung organogenesis
Published in PloS one (03-08-2011)“…Follistatin-like 1 (Fstl1) is a secreted protein of the BMP inhibitor class. During development, expression of Fstl1 is already found in cleavage stage embryos…”
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The expressions and significance of APN, D-D, IL-17 and hs-CRP in patients with acute exacerbation of chronic obstructive pulmonary disease
Published in European review for medical and pharmacological sciences (01-10-2018)“…Inflammatory reactions and imbalance of oxidant/antioxidant and protease/anti-protease are the major causes of chronic obstructive pulmonary disease. Based on…”
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A wind tunnel study of effects of twisted wind flows on the pedestrian-level wind field in an urban environment
Published in Building and environment (15-01-2018)“…The influence of twisted wind flows on the pedestrian-level wind (PLW) field of an urban area was evaluated by testing a typical urban site (Tsuen Wan, Hong…”
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17
Extrinsic anomalous Hall effect in epitaxial Mn4N films
Published in Applied physics letters (19-01-2015)“…Anomalous Hall effect (AHE) in ferrimagnetic Mn4N epitaxial films grown by molecular-beam epitaxy is investigated. The longitudinal conductivity σxx is within…”
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Adopting ‘lift-up’ building design to improve the surrounding pedestrian-level wind environment
Published in Building and environment (15-05-2017)“…Modern megacities are teeming with closely-spaced tall buildings, which limit air circulation at the pedestrian level. The resultant lack of air circulation…”
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The Quest for High-Performance Host Materials for Electrophosphorescent Blue Dopants
Published in Advanced functional materials (13-08-2007)“…We report a systematic comparison study of 3,5‐di(N‐carbazolyl)tetraphenylsilane (SimCP) and N,N′‐dicarbazolyl‐3,5‐benzene (mCP), which are used as the host…”
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In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration
Published in Nature (London) (14-02-2013)“…A mouse model of liver damage has identified a population of Lrg5 + liver stem cells that can generate hepatoctyes and bile ducts in vivo. Wake-up call for…”
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